Effect of the introduction of a management bundle for blood culture collection.

Blood culture Bundle Chlorhexidine alcohol Collection from superficial veins of the cubital fossa Contamination

Journal

American journal of infection control
ISSN: 1527-3296
Titre abrégé: Am J Infect Control
Pays: United States
ID NLM: 8004854

Informations de publication

Date de publication:
07 2022
Historique:
received: 24 08 2021
revised: 19 11 2021
accepted: 20 11 2021
pubmed: 6 12 2021
medline: 24 6 2022
entrez: 5 12 2021
Statut: ppublish

Résumé

Inappropriate blood collection subjected to blood culture (BC) causes BC contamination and may complicate the diagnose is of infectious diseases. Therefore, we developed a bundle based on the guideline recommendations for appropriate blood collection and examined the effects of bundle introduction. We performed a retrospective analysis of BC samples to determine the contamination rates before and after introducing the BC bundle. We also analyzed the correlation between the compliance rate of the bundle and contamination rate, and between each bundle element and contamination. After the introduction of the bundle, the contamination rate was significantly reduced from 5.4% ± 0.9% to 1.7± 0.7% (P < .01). The compliance rate of the bundle was significantly associated with a lower contamination rate (P < .01). Multivariable logistic regression showed that collection from superficial veins of the cubital fossa (odds ratio [OR], 0.25; 95% confidence interval [CI], 0.13-0.51, P < .01) and disinfection of the skin at the blood collection site with 1% chlorhexidine alcohol swab (OR, 0.41; 95% CI, 0.25-0.68, P < .01) were significantly associated with lower contamination. This study suggests that the introduction of the BC bundle significantly reduced the contamination rate, and bundle compliance was associated with a lower contamination rate.

Sections du résumé

BACKGROUND
Inappropriate blood collection subjected to blood culture (BC) causes BC contamination and may complicate the diagnose is of infectious diseases. Therefore, we developed a bundle based on the guideline recommendations for appropriate blood collection and examined the effects of bundle introduction.
METHODS
We performed a retrospective analysis of BC samples to determine the contamination rates before and after introducing the BC bundle. We also analyzed the correlation between the compliance rate of the bundle and contamination rate, and between each bundle element and contamination.
RESULTS
After the introduction of the bundle, the contamination rate was significantly reduced from 5.4% ± 0.9% to 1.7± 0.7% (P < .01). The compliance rate of the bundle was significantly associated with a lower contamination rate (P < .01). Multivariable logistic regression showed that collection from superficial veins of the cubital fossa (odds ratio [OR], 0.25; 95% confidence interval [CI], 0.13-0.51, P < .01) and disinfection of the skin at the blood collection site with 1% chlorhexidine alcohol swab (OR, 0.41; 95% CI, 0.25-0.68, P < .01) were significantly associated with lower contamination.
CONCLUSIONS
This study suggests that the introduction of the BC bundle significantly reduced the contamination rate, and bundle compliance was associated with a lower contamination rate.

Identifiants

pubmed: 34863897
pii: S0196-6553(21)00786-0
doi: 10.1016/j.ajic.2021.11.019
pii:
doi:

Substances chimiques

Anti-Infective Agents, Local 0
Chlorhexidine R4KO0DY52L

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

772-776

Informations de copyright

Copyright © 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Auteurs

Kenta Minami (K)

Infection Control Center, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan; Department of Central Clinical Laboratory, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan. Electronic address: kenta.minami@ompu.ac.jp.

Tomoyuki Yamada (T)

Infection Control Center, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan; Department of Pharmacy, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.

Kyouhei Yoshioka (K)

Infection Control Center, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.

Fumiko Kawanishi (F)

Infection Control Center, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.

Taku Ogawa (T)

Infection Control Center, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan; Department of Microbiology and Infection Control, Osaka Medical and Pharmaceutical University, Osaka, Japan.

Akira Ukimura (A)

Infection Control Center, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan; Department of Central Clinical Laboratory, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.

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Classifications MeSH