Does Sleeve Gastrectomy Worsen Gastroesophageal Reflux Disease in Obese Patients? A Prospective Study.

24h-pH-impedance bariatric surgery gastroesophageal reflux disease (GERD) laparoscopic gastric bypass laparoscopic sleeve gastrectomy manometry pH-manometry

Journal

Surgical innovation
ISSN: 1553-3514
Titre abrégé: Surg Innov
Pays: United States
ID NLM: 101233809

Informations de publication

Date de publication:
Oct 2022
Historique:
pubmed: 7 12 2021
medline: 29 10 2022
entrez: 6 12 2021
Statut: ppublish

Résumé

To evaluate the impact of laparoscopic sleeve gastrectomy (LSG) and gastric bypass (LGB) on gastroesophageal reflux disease (GERD). GERD was evaluated by the Modified Italian Gastroesophageal reflux disease-Health-Related Quality of Life (MI-GERD-HRQL) questionnaire, pH-manometry, endoscopy, and Rx-esophagogram, before and 12 months after surgery. Based on these exams, patients without GERD underwent LSG, and patients with GERD underwent LGB. Thirteen and six patients underwent LSG and LGB, respectively. After LSG, the only statistically significant difference observed at pH-manometry was the median DeMeester score, from 5.7 to 22.7 (P = .0026). LSG has a negative impact on GERD, even in patients without preoperative GERD. LGB confirmed to be the intervention of choice in patients with GERD. Preoperative pH-manometry may identify patients with silent GERD, to candidate them to LGB rather than LSG. pH-manometry should be used more liberally to establish the correct surgical indication on objective grounds.

Sections du résumé

BACKGROUND BACKGROUND
To evaluate the impact of laparoscopic sleeve gastrectomy (LSG) and gastric bypass (LGB) on gastroesophageal reflux disease (GERD).
METHODS METHODS
GERD was evaluated by the Modified Italian Gastroesophageal reflux disease-Health-Related Quality of Life (MI-GERD-HRQL) questionnaire, pH-manometry, endoscopy, and Rx-esophagogram, before and 12 months after surgery. Based on these exams, patients without GERD underwent LSG, and patients with GERD underwent LGB.
RESULTS RESULTS
Thirteen and six patients underwent LSG and LGB, respectively. After LSG, the only statistically significant difference observed at pH-manometry was the median DeMeester score, from 5.7 to 22.7 (P = .0026).
CONCLUSIONS CONCLUSIONS
LSG has a negative impact on GERD, even in patients without preoperative GERD. LGB confirmed to be the intervention of choice in patients with GERD. Preoperative pH-manometry may identify patients with silent GERD, to candidate them to LGB rather than LSG. pH-manometry should be used more liberally to establish the correct surgical indication on objective grounds.

Identifiants

pubmed: 34865557
doi: 10.1177/15533506211052745
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

579-589

Auteurs

Andrea Balla (A)

Department of General Surgery and Surgical Specialties "Paride Stefanini", 9311Sapienza University of Rome, Rome, Italy.

Livia Palmieri (L)

Department of General Surgery and Surgical Specialties "Paride Stefanini", 9311Sapienza University of Rome, Rome, Italy.

Diletta Corallino (D)

Department of General Surgery and Surgical Specialties "Paride Stefanini", 9311Sapienza University of Rome, Rome, Italy.

Francesca Meoli (F)

Department of General Surgery and Surgical Specialties "Paride Stefanini", 9311Sapienza University of Rome, Rome, Italy.

Maria Carlotta Sacchi (M)

Department of Translational and Precision Medicine, 9311Sapienza University of Rome, Rome, Italy.

Emanuela Ribichini (E)

Department of Translational and Precision Medicine, 9311Sapienza University of Rome, Rome, Italy.

Annamaria Pronio (A)

Digestive Endoscopy Unit, Department of General Surgery and Surgical Specialties "Paride Stefanini", 9311Sapienza University of Rome, Rome, Italy.

Danilo Badiali (D)

Department of Translational and Precision Medicine, 9311Sapienza University of Rome, Rome, Italy.

Alessandro M Paganini (AM)

Department of General Surgery and Surgical Specialties "Paride Stefanini", 9311Sapienza University of Rome, Rome, Italy.

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