Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy.
IGRT
Nanoparticles
Theranostics
Titanium peroxide
Journal
Physics and imaging in radiation oncology
ISSN: 2405-6316
Titre abrégé: Phys Imaging Radiat Oncol
Pays: Netherlands
ID NLM: 101704276
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
30
07
2021
revised:
12
11
2021
accepted:
12
11
2021
entrez:
6
12
2021
pubmed:
7
12
2021
medline:
7
12
2021
Statut:
epublish
Résumé
Metal-based nanoparticles (NPs) have been extensively studied for dose enhancement applications in radiation therapy. This study investigated the utility of such NPs for image-guided radiation therapy (IGRT). Phantom images of gold NPs (AuNPs) and titanium peroxide NPs (TiOxNPs) with different concentrations were acquired using IGRT modalities, including cone-beam computed tomography (CBCT). AuNPs induced strong contrast enhancement in kV energy CBCT images, whereas TiOxNPs at high concentrations showed weak but detectable changes. The results indicated that these NPs can be used to enhance IGRT images as well as dose enhancement for treatment purposes.
Identifiants
pubmed: 34869923
doi: 10.1016/j.phro.2021.11.003
pii: S2405-6316(21)00067-1
pmc: PMC8626564
doi:
Types de publication
Journal Article
Langues
eng
Pagination
94-97Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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