Evaluation of biochemical characteristics of 183 COVID-19 patients: A retrospective study.

Biochemical parameters COVID-19 Golestan

Journal

Gene reports
ISSN: 2452-0144
Titre abrégé: Gene Rep
Pays: United States
ID NLM: 101680713

Informations de publication

Date de publication:
Mar 2022
Historique:
received: 30 07 2021
revised: 01 11 2021
accepted: 16 11 2021
entrez: 6 12 2021
pubmed: 7 12 2021
medline: 7 12 2021
Statut: ppublish

Résumé

Coronavirus disease 2019 (COVID-19), with a high mortality rate, has caught the eyes of researchers worldwide and placed a heavy burden on the health care system. Accordingly, this study aimed to evaluate the values of biochemical parameters on the outcomes of COVID-19 patients in Golestan, Iran. This retrospective study was conducted on 183 COVID-19 patients (i.e., 94 males and 89 females) between March and September 2020. The biochemical parameters and demographic data of the patients (including age, sex, urea, creatinine [Cr], lactate dehydrogenase [LDH], and creatine kinase [CK]) were obtained from electrical medical records. According to the outcome of COVID-19, the patients were categorized into two groups (i.e., death [ Of the 183 patients, 120 (65.5%) had a non-severe type and recovered from COVID-19, and 63 (34.4%) developed into a critically severe type and died. The mean age of all patients was 56.5 years old. The highest mortality was observed in patients with LDH ≥280. The data obtained by the one-sample Some biochemical parameters are effective in the evaluation of dynamic variations in COVID-19 patients. It can be concluded from the results that biochemical parameters and reinforce LDH may be useful for the evaluation of the COVID-19 outcome.

Identifiants

pubmed: 34869941
doi: 10.1016/j.genrep.2021.101448
pii: S2452-0144(21)00432-5
pmc: PMC8626347
doi:

Types de publication

Journal Article

Langues

eng

Pagination

101448

Informations de copyright

© 2021 Published by Elsevier Inc.

Déclaration de conflit d'intérêts

All authors (Seyed Mostafa Mir, Alireza Tahamtan, Hadi Razavi Nikoo, Mehdi Sheikh Arabi, Abdul Wahab Moradi, Alijan Tabarraei) have approved the manuscript and agree with submission. The authors declare that there are no conflicts of interest to the publication of this article, financial and/or otherwise. The final manuscript has been seen and approved by all authors and that they have taken due care to ensure the integrity of the work. The authors declare that there is no conflict of interest.

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Auteurs

Seyed Mostafa Mir (SM)

Metabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran.

Alireza Tahamtan (A)

Infectious Diseases Research Centre, Golestan University of Medical Sciences, Gorgan, Iran.
Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.

Hadi Razavi Nikoo (HR)

Infectious Diseases Research Centre, Golestan University of Medical Sciences, Gorgan, Iran.
Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.

Mehdi Sheikh Arabi (MS)

Medical Cellular and Molecular Research Center, Golestan University of Medical Sciences, Gorgan, Iran.

Abdul Wahab Moradi (AW)

Infectious Diseases Research Centre, Golestan University of Medical Sciences, Gorgan, Iran.
Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.

Saeed Ardakanian (S)

Metabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran.

Alijan Tabarraei (A)

Infectious Diseases Research Centre, Golestan University of Medical Sciences, Gorgan, Iran.
Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.

Classifications MeSH