Generic Pharmaceuticals as a Source of Diuretic Contamination in Athletes Subject to Sport Drug Testing.
adverse analytical finding
anti-doping
minimum reporting level
prescription medication
rule violation
Journal
Frontiers in sports and active living
ISSN: 2624-9367
Titre abrégé: Front Sports Act Living
Pays: Switzerland
ID NLM: 101765780
Informations de publication
Date de publication:
2021
2021
Historique:
received:
07
04
2021
accepted:
25
10
2021
entrez:
6
12
2021
pubmed:
7
12
2021
medline:
7
12
2021
Statut:
epublish
Résumé
This paper describes nine instances of positive anti-doping tests that could be accounted for by the use of permitted generic prescription drugs contaminated with diuretics, which are prohibited in sport at all times under the WADA Prohibited List. The contamination levels found in the medications are reported and were below FDA limits for manufacturers that are based primarily on safety considerations. These cases demonstrate that great care must be taken to identify the source of low-level anti-doping positives for diuretics reported by WADA-accredited laboratories, and possibly other prohibited substances as well, in order to avoid sanctioning innocent athletes. An evaluation of the cases in this paper supports an approach which establishes a laboratory minimum reporting level (MRL) for diuretics found most commonly in medications. A global consensus after extensive review of similar anti-doping cases has resulted in implementation of a recently announced solution regarding potential diuretic contamination cases.
Identifiants
pubmed: 34870192
doi: 10.3389/fspor.2021.692244
pmc: PMC8635962
doi:
Types de publication
Journal Article
Langues
eng
Pagination
692244Informations de copyright
Copyright © 2021 Eichner, Lewis, Leonard, Wagoner, Eichner and Fedoruk.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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