A Radiology-focused Review of Predictive Uncertainty for AI Interpretability in Computer-assisted Segmentation.

Bayesian Network (BN) Ethics Quantification Segmentation

Journal

Radiology. Artificial intelligence
ISSN: 2638-6100
Titre abrégé: Radiol Artif Intell
Pays: United States
ID NLM: 101746556

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 22 01 2021
revised: 09 08 2021
accepted: 25 08 2021
entrez: 6 12 2021
pubmed: 7 12 2021
medline: 7 12 2021
Statut: epublish

Résumé

The recent advances and availability of computer hardware, software tools, and massive digital data archives have enabled the rapid development of artificial intelligence (AI) applications. Concerns over whether AI tools can "communicate" decisions to radiologists and primary care physicians is of particular importance because automated clinical decisions can substantially impact patient outcome. A challenge facing the clinical implementation of AI stems from the potential lack of trust clinicians have in these predictive models. This review will expand on the existing literature on interpretability methods for deep learning and review the state-of-the-art methods for predictive uncertainty estimation for computer-assisted segmentation tasks. Last, we discuss how uncertainty can improve predictive performance and model interpretability and can act as a tool to help foster trust.

Identifiants

pubmed: 34870219
doi: 10.1148/ryai.2021210031
pmc: PMC8637228
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

e210031

Informations de copyright

2021 by the Radiological Society of North America, Inc.

Déclaration de conflit d'intérêts

Disclosures of Conflicts of Interest: B.M. Institution received grant from Defence Research and Development Canada (grant number CFPMN2-017-McMaster) for the Innovation for Defence Excellence and Security program presented by the DRDC. K.Z. Consultant for the Centre for Probe Development and Commercialization. T.E.D. No relevant relationships. M.D.N. Data analytics consultant for MCI OneHealth; CEO and cofounder of TBI Finder.

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Auteurs

Brian McCrindle (B)

Department of Electrical and Computer Engineering (B.M., T.E.D., M.D.N.), Department of Radiology, Faculty of Health Sciences (K.Z., M.D.N.), and School of Biomedical Engineering (K.Z., T.E.D., M.D.N.), McMaster University, 1280 Main St W, Hamilton, ON, Canada L8S 4L8; and Vector Institute for Artificial Intelligence, Toronto, Canada (T.E.D.).

Katherine Zukotynski (K)

Department of Electrical and Computer Engineering (B.M., T.E.D., M.D.N.), Department of Radiology, Faculty of Health Sciences (K.Z., M.D.N.), and School of Biomedical Engineering (K.Z., T.E.D., M.D.N.), McMaster University, 1280 Main St W, Hamilton, ON, Canada L8S 4L8; and Vector Institute for Artificial Intelligence, Toronto, Canada (T.E.D.).

Thomas E Doyle (TE)

Department of Electrical and Computer Engineering (B.M., T.E.D., M.D.N.), Department of Radiology, Faculty of Health Sciences (K.Z., M.D.N.), and School of Biomedical Engineering (K.Z., T.E.D., M.D.N.), McMaster University, 1280 Main St W, Hamilton, ON, Canada L8S 4L8; and Vector Institute for Artificial Intelligence, Toronto, Canada (T.E.D.).

Michael D Noseworthy (MD)

Department of Electrical and Computer Engineering (B.M., T.E.D., M.D.N.), Department of Radiology, Faculty of Health Sciences (K.Z., M.D.N.), and School of Biomedical Engineering (K.Z., T.E.D., M.D.N.), McMaster University, 1280 Main St W, Hamilton, ON, Canada L8S 4L8; and Vector Institute for Artificial Intelligence, Toronto, Canada (T.E.D.).

Classifications MeSH