Neuromuscular sonography detects changes in muscle echotexture and nerve diameter in ICU patients within 24 h.
Cross-sectional area
Gray-scale analysis
ICU-AW
Muscle ultrasound
Nerve ultrasound
Journal
Journal of ultrasound
ISSN: 1876-7931
Titre abrégé: J Ultrasound
Pays: Italy
ID NLM: 101315005
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
07
06
2021
accepted:
25
08
2021
pubmed:
7
12
2021
medline:
27
8
2022
entrez:
6
12
2021
Statut:
ppublish
Résumé
During an ICU stay, changes in muscles and nerves occur that is accessible via neuromuscular sonography. 17 patients recruited from the neurological and neurosurgical ICU (six women; 66 ± 3 years) and 7 healthy controls (three women, 75 ± 3 years) were included. Muscle sonography (rectus abdominis, biceps, rectus femoris and tibialis anterior muscles) using gray-scale values (GSVs), and nerve ultrasound (peroneal, tibial and sural nerves) analyzing the cross-sectional area (CSA) were performed on days 1 (t1), 3 (t2), 5 (t3), 8 (t4), and 16 (t5) after admission. Time course analysis revealed that GSVs were significantly higher within the patient group for all of the investigated muscles (rectus abdominis: F = 7.536; p = 0.011; biceps: F = 14.761; p = 0.001; rectus femoris: F = 9.455; p = 0.005; tibialis anterior: F = 7.282; p = 0.012). The higher GSVs were already visible at t1 or, at the latest, at t2 (tibialis anterior muscles). CSA was enlarged in all of the investigated nerves in the patient group (peroneal nerve: F = 7.129; p = 0.014; tibial nerve: F = 28.976, p < 0.001; sural nerve: F = 13.051; p = 0.001). The changes were visible very early (tibial nerve: t1; peroneal nerve: t2). The CSA of the motor nerves showed an association with the ventilation time and days within the ICU (t1 through t4; p < 0.05). We detected very early changes in the muscles and nerves of ICU-patients. Nerve CSA might be a useful parameter to identify patients who are at risk for difficult weaning. Therefore our observations might be severity signs of neuromuscular suffering for the most severe patients.
Identifiants
pubmed: 34870825
doi: 10.1007/s40477-021-00621-8
pii: 10.1007/s40477-021-00621-8
pmc: PMC9402876
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
535-545Informations de copyright
© 2021. The Author(s).
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