The role of cytology as an effective tool in management of omental and peritoneal lesions: Experience of a large health care system.
cancer
cytology
fine-needle aspiration
management
peritoneal lesions
tool
Journal
Diagnostic cytopathology
ISSN: 1097-0339
Titre abrégé: Diagn Cytopathol
Pays: United States
ID NLM: 8506895
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
revised:
25
09
2021
received:
10
03
2021
accepted:
26
11
2021
pubmed:
7
12
2021
medline:
22
3
2022
entrez:
6
12
2021
Statut:
ppublish
Résumé
The aim of this study is to assess the efficacy of cytology in omental or peritoneal lesions. A retrospective review of the pathology database for cytology cases of peritoneal or omental nodules over a 3-year period (2016-2018) was conducted. The cases consisted of either FNA only (FO); FNA and Core biopsy (FCB) or Touch prep and core biopsy (TCB). Cases were further divided based on the prior history of carcinoma. Concordance rates of cytologic diagnosis with histologic diagnosis were studied. Out of 104 cytology cases reviewed, 60 (57.7%) had prior history of cancer (PHC) and 44 (42.3%) had no prior history of cancer (NPHC). Of the cases with PHC, 43(71.66%) were recurrence, 10 (16.66%) were second cancer, and 7 (11.66%) were non-neoplastic lesions. Of the cases with NPHC, 38 (86.4%) had a second cancer diagnosis, while 6 (13.6%) were non-neoplastic. For FO only cases, 11 of 35 (31.4%) had follow up and 9 of 11 (81.8%) were concordant. For FCB cases, 6 out of 39 (15.4%) had follow up and 6 (100%) were concordant. For TCB cases, 9 out of 30 (30%) had follow up and 9 (100%) were concordant. A definite diagnosis was reached in 30/35, 39/39, and 29/30 cases in FO, FCB, and TCB, respectively. In summary, cytologic evaluation of omental lesions is an effective tool in providing accurate diagnosis and guiding further management. Also, the results based on our study show that the combined techniques are superior at reaching a definitive diagnosis.
Sections du résumé
BACKGROUND
BACKGROUND
The aim of this study is to assess the efficacy of cytology in omental or peritoneal lesions.
METHODS
METHODS
A retrospective review of the pathology database for cytology cases of peritoneal or omental nodules over a 3-year period (2016-2018) was conducted. The cases consisted of either FNA only (FO); FNA and Core biopsy (FCB) or Touch prep and core biopsy (TCB). Cases were further divided based on the prior history of carcinoma. Concordance rates of cytologic diagnosis with histologic diagnosis were studied.
RESULTS
RESULTS
Out of 104 cytology cases reviewed, 60 (57.7%) had prior history of cancer (PHC) and 44 (42.3%) had no prior history of cancer (NPHC). Of the cases with PHC, 43(71.66%) were recurrence, 10 (16.66%) were second cancer, and 7 (11.66%) were non-neoplastic lesions. Of the cases with NPHC, 38 (86.4%) had a second cancer diagnosis, while 6 (13.6%) were non-neoplastic. For FO only cases, 11 of 35 (31.4%) had follow up and 9 of 11 (81.8%) were concordant. For FCB cases, 6 out of 39 (15.4%) had follow up and 6 (100%) were concordant. For TCB cases, 9 out of 30 (30%) had follow up and 9 (100%) were concordant. A definite diagnosis was reached in 30/35, 39/39, and 29/30 cases in FO, FCB, and TCB, respectively.
CONCLUSION
CONCLUSIONS
In summary, cytologic evaluation of omental lesions is an effective tool in providing accurate diagnosis and guiding further management. Also, the results based on our study show that the combined techniques are superior at reaching a definitive diagnosis.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
57-63Informations de copyright
© 2021 Wiley Periodicals LLC.
Références
Vadvala H, Furtado VF, Kambadakone A, Frenk NE, Mueller PR, Arellano RS. Image-guided percutaneous Omental and mesenteric biopsy: assessment of technical success rate and diagnostic yield. J Vasc Interv Radiol. 2017;28(11):1569-1576. doi:10.1016/j.jvir.2017.07.001
Tirkes T, Sandrasegaran K, Patel AA, et al. Peritoneal and retroperitoneal anatomy and its relevance for cross-sectional imaging. Radiographics. 2012;32:437-451. doi:10.1148/rg.322115032
Healy JC, Reznek RH. The peritoneum, mesenteries and omenta: normal anatomy and pathological processes. Eur Radiol. 1998;8:886-900. doi:10.1007/s003300050485
Baker PM, Clement PB, Young RH. Selected topics in peritoneal pathology. Int J Gynecol Pathol. 2014;33(4):393-401. doi:10.1097/PGP.0000000000000146
Reyaz TA, Summyia F, Isma S, et al. USG guided fine needle aspiration cytology of intra-abdominal and pelvic masses in Kashmir: a study at tertiary care hospital. Int J Med Res Health Sci. 2016;5(4):169-175.
Stewart CJR, Coldewey J, Stewart IS. Comparison of fine needle aspiration cytology and needle core biopsy in the diagnosis of radiologically detected abdominal lesions. J Clin Pathol. 2002;55:93-97.
Khan AA, Jan GM, Wani NA. Fine needle aspiration of intraabdominal masses for cytodiagnosis. J Indian Med Assoc. 1996;94(5):167-169.
Zawar MP, Bolde S, Shete SS. Correlative study of fine needle aspiration cytology and histology in intra-abdominal lumps. SMJ. 2007;4.
Clement PB. Tumors of the peritoneum. In: Fletcher CDM, ed. Diagnostic Histopathology of Tumors. Churchill Livingstone; 1995:611-633.
Pickhardt PJ, Bhalla S. Primary neoplasms of peritoneal and sub- peritoneal origin: CT findings. Radiographics. 2005;25:983-995.
Lin O. Challenges in the interpretation of peritoneal cytologic specimens. Arch Pathol Lab Med. 2009;133(5):739-742. doi:10.5858/133.5.739
Layfield LJ, Gopez EV. Percutaneous image-guided fine-needle aspiration of peritoneal lesions. Diagn Cytopathol. 2003 Jan;28(1):6-12. doi:10.1002/dc.10217
Lee KR, Scully RE. Mucinous tumors of the ovary: a clinicopathologic study of 196 borderline tumours (of intestinal type) and carcinomas, including an evaluation of 11 cases with “pseudomyxoma peritonei”. Am J Surg Pathol. 2000;24:1447-1464.
Weir MM, Bell DA, Young RH. Grade 1 peritoneal serous carcinomas: a report of 14 cases and comparison with 7 peritoneal serous psammocarcinomas and 19 peritoneal serous borderline tumors. Am J Surg Pathol. 1998;22:849-862.
Bell DA, Scully RE. Serous borderline tumors of the peritoneum. Am J Surg Pathol. 1990;14:230-239.
Bell DA, Weinstock MA, Scully RE. Peritoneal implants of ovarian serous borderline tumors. Cancer. 1988;62:2212-2222.
Ballo MS, Guy CD. Percutaneous fine-needle aspiration of gastrointestinal wall lesions with image guidance. Diagn Cytopathol. 2001;24:16-20.