Surgical data science - from concepts toward clinical translation.

Artificial intelligence Clinical translation Computer aided surgery Deep learning Surgical data science

Journal

Medical image analysis
ISSN: 1361-8423
Titre abrégé: Med Image Anal
Pays: Netherlands
ID NLM: 9713490

Informations de publication

Date de publication:
02 2022
Historique:
received: 10 11 2020
revised: 03 11 2021
accepted: 08 11 2021
pubmed: 9 12 2021
medline: 8 4 2022
entrez: 8 12 2021
Statut: ppublish

Résumé

Recent developments in data science in general and machine learning in particular have transformed the way experts envision the future of surgery. Surgical Data Science (SDS) is a new research field that aims to improve the quality of interventional healthcare through the capture, organization, analysis and modeling of data. While an increasing number of data-driven approaches and clinical applications have been studied in the fields of radiological and clinical data science, translational success stories are still lacking in surgery. In this publication, we shed light on the underlying reasons and provide a roadmap for future advances in the field. Based on an international workshop involving leading researchers in the field of SDS, we review current practice, key achievements and initiatives as well as available standards and tools for a number of topics relevant to the field, namely (1) infrastructure for data acquisition, storage and access in the presence of regulatory constraints, (2) data annotation and sharing and (3) data analytics. We further complement this technical perspective with (4) a review of currently available SDS products and the translational progress from academia and (5) a roadmap for faster clinical translation and exploitation of the full potential of SDS, based on an international multi-round Delphi process.

Identifiants

pubmed: 34879287
pii: S1361-8415(21)00351-0
doi: 10.1016/j.media.2021.102306
pmc: PMC9135051
mid: NIHMS1802848
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102306

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK123445
Pays : United States
Organisme : NIBIB NIH HHS
ID : P41 EB015898
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE025265
Pays : United States
Organisme : Wellcome Trust
ID : 203145Z/16/Z
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : R01 CA235589
Pays : United States
Organisme : NIBIB NIH HHS
ID : P41 EB028741
Pays : United States
Organisme : NIBIB NIH HHS
ID : P41 EB015902
Pays : United States

Informations de copyright

Copyright © 2021. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of Competing Interest Anand Malpani is a future employee at Mimic Technologies Inc. (Seattle, WA, US). Johannes Fallert and Lars Mündermann are employed at KARL STORZ SE & Co. KG (Tuttlingen, Germany). Hirenkumar Nakawala is employed at CMR Surgical Ltd (Cambridge, UK). Nicolas Padoy is a scientific advisor of Caresyntax (Berlin, Germany). Daniel A. Hashimoto is a consultant for Johnson & Johnson (New Brunswick, NJ, USA), Verily Life Sciences (San Francisco, CA, USA), and Activ Surgical (Boston, MA, USA). He has received research support from Olympus Corporation and the Intuitive Foundation. Carla Pugh is the founder of 10 Newtons Inc. (Madison, WI, US). Danail Stoyanov is employed at Digital Surgery Ltd (London, UK) and Odin Vision Ltd (London, UK). Teodor Grantcharov is the founder of Surgical Safety Technologies Inc. (Toronto, Ontario, Canada). Tobias Roß is employed at Quality Match GmbH (Heidelberg, Germany). All other authors do not declare any conflicts of interest.

Références

Lancet Respir Med. 2018 Dec;6(12):905-914
pubmed: 30274956
J Med Imaging (Bellingham). 2020 May;7(3):031502
pubmed: 32090136
Med Image Anal. 2021 May;70:101920
pubmed: 33676097
Ann Surg. 2020 Jan;271(1):122-127
pubmed: 29916872
Surg Endosc. 2020 Jun;34(6):2709-2714
pubmed: 31583466
IEEE Eng Med Biol Mag. 2005 Mar-Apr;24(2):122, 124
pubmed: 15825856
Surg Endosc. 2021 Sep;35(9):4918-4929
pubmed: 34231065
Int J Comput Assist Radiol Surg. 2016 Apr;11(4):679
pubmed: 26704373
Surg Innov. 2011 Mar;18(1):8-14
pubmed: 21385758
Nat Commun. 2018 Dec 6;9(1):5217
pubmed: 30523263
Am Soc Clin Oncol Educ Book. 2013;:430-4
pubmed: 23714566
Med Image Comput Comput Assist Interv. 2005;8(Pt 2):139-46
pubmed: 16685953
Phys Med Biol. 2019 Aug 21;64(16):165020
pubmed: 31247607
J Digit Imaging. 2016 Apr;29(2):206-15
pubmed: 26482912
Int J Comput Assist Radiol Surg. 2020 May;15(5):827-836
pubmed: 32323210
J Surg Res. 2018 Jan;221:336-342
pubmed: 29229148
Ann Surg. 2022 Aug 1;276(2):363-369
pubmed: 33196488
Int J Comput Assist Radiol Surg. 2015 Jun;10(6):737-47
pubmed: 25847670
Ann Surg. 2021 Jul 1;274(1):e93-e95
pubmed: 33417329
Ann Surg. 2020 Sep 1;272(3):523-528
pubmed: 33759839
Surg Endosc. 2021 Apr;35(4):1651-1658
pubmed: 32306111
BMJ. 2002 Jun 15;324(7351):1448-51
pubmed: 12065273
Nat Biomed Eng. 2017 Sep;1(9):691-696
pubmed: 31015666
JAMA Surg. 2017 Oct 1;152(10):972-973
pubmed: 28813552
Breast Care (Basel). 2018 Oct;13(5):349-353
pubmed: 30498420
Sci Rep. 2020 Feb 17;10(1):2748
pubmed: 32066744
Int J Comput Assist Radiol Surg. 2016 Jun;11(6):881-8
pubmed: 27025604
Surg Endosc. 2019 May;33(5):1532-1543
pubmed: 30209607
Int J Comput Assist Radiol Surg. 2015 Sep;10(9):1435-47
pubmed: 26133652
IEEE Trans Med Imaging. 2017 Jan;36(1):86-97
pubmed: 27455522
NPJ Digit Med. 2019 Apr 30;2:31
pubmed: 31304378
N Engl J Med. 2019 Oct 24;381(17):1684-1686
pubmed: 31644852
Nat Biotechnol. 2007 Nov;25(11):1251-5
pubmed: 17989687
IEEE Trans Neural Syst Rehabil Eng. 2016 Feb;24(2):300-7
pubmed: 26415181
Visc Med. 2020 Dec;36(6):456-462
pubmed: 33447601
Ann Surg. 2022 May 1;275(5):955-961
pubmed: 33201104
Surg Innov. 2022 Feb;29(1):98-102
pubmed: 33830831
Nat Med. 2018 Nov;24(11):1716-1720
pubmed: 30349085
J Visc Surg. 2021 Jun;158(3S):S18-S25
pubmed: 33712411
Proc ACM Conf Health Inference Learn (2020). 2020 Apr;2020:151-159
pubmed: 33196064
Can J Anaesth. 2016 Feb;63(2):176-83
pubmed: 26475163
J Clin Monit Comput. 2021 Feb;35(1):113-121
pubmed: 31902095
Thorac Cancer. 2020 May;11(5):1265-1270
pubmed: 32191394
JCO Clin Cancer Inform. 2018 Dec;2:1-8
pubmed: 30652564
Surgery. 2020 Oct;168(4):643-652
pubmed: 32792098
Acta Otorhinolaryngol Ital. 2017 Jun;37(3):237-241
pubmed: 28516968
Surgery. 2005 May;137(5):518-26
pubmed: 15855924
IEEE Trans Med Imaging. 2016 May;35(5):1313-21
pubmed: 26891484
Eur Radiol. 2019 Mar;29(3):1391-1399
pubmed: 30194472
Sci Data. 2021 Apr 12;8(1):101
pubmed: 33846356
Ann Surg. 2017 Nov;266(5):890-897
pubmed: 28742709
Yearb Med Inform. 2016 Nov 10;(1):184-187
pubmed: 27830249
JAMA Surg. 2018 Sep 1;153(9):852-853
pubmed: 29617536
Obes Surg. 2018 Sep;28(9):2634-2643
pubmed: 29633151
Annu Rev Biomed Eng. 2017 Jun 21;19:221-248
pubmed: 28301734
IEEE Trans Pattern Anal Mach Intell. 2018 Dec;40(12):2814-2826
pubmed: 29989983
Radiographics. 2006 Nov-Dec;26(6):1595-7
pubmed: 17102038
Int J Comput Assist Radiol Surg. 2020 Apr;15(4):673-680
pubmed: 32040704
Med Image Anal. 2016 May;30:144-157
pubmed: 26970592
Sci Data. 2016 Mar 15;3:160018
pubmed: 26978244
Nat Neurosci. 2017 Feb 23;20(3):299-303
pubmed: 28230846
J Surg Oncol. 2018 Aug;118(2):265-282
pubmed: 30076724
Med Image Comput Comput Assist Interv. 2014;17(Pt 2):438-45
pubmed: 25485409
Med Image Comput Comput Assist Interv. 2008;11(Pt 2):467-75
pubmed: 18982638
JAMA. 2020 Mar 17;323(11):1052-1060
pubmed: 32065827
Radiology. 2018 Mar;286(3):810-818
pubmed: 29039725
Surg Endosc. 2020 Mar;34(3):1077-1087
pubmed: 31161291
IEEE Trans Pattern Anal Mach Intell. 2013 Jan;35(1):130-43
pubmed: 22450819
J Clin Med. 2020 Jan 27;9(2):
pubmed: 32012659
Endosc Int Open. 2017 Jun;5(6):E477-E483
pubmed: 28580415
J Am Coll Surg. 2014 Feb;218(2):170-8
pubmed: 24440064
Stud Health Technol Inform. 2005;115:153-73
pubmed: 16160223
Int J Comput Assist Radiol Surg. 2020 May;15(5):771-779
pubmed: 32323212
Sci Rep. 2020 Mar 20;10(1):5143
pubmed: 32198487
Int J Comput Assist Radiol Surg. 2020 May;15(5):759-769
pubmed: 32333361
J Hosp Med. 2017 Mar;12(3):193-198
pubmed: 28272599
Comput Assist Surg (Abingdon). 2021 Dec;26(1):58-68
pubmed: 34126014
Ann Oncol. 2018 Feb 1;29(2):418-423
pubmed: 29324970
J Am Med Inform Assoc. 2002 Nov-Dec;9(6):600-11
pubmed: 12386111
Minim Invasive Ther Allied Technol. 2019 Apr;28(2):82-90
pubmed: 30849261
Int J Comput Assist Radiol Surg. 2019 Jun;14(6):997-1007
pubmed: 30903566
Neural Netw. 2019 May;113:54-71
pubmed: 30780045
Nature. 2008 Jun 12;453(7197):840-2
pubmed: 18548043
Med Image Anal. 2012 Apr;16(3):632-41
pubmed: 21195015
NPJ Digit Med. 2020 Sep 14;3:119
pubmed: 33015372
Gastric Cancer. 2018 Jul;21(4):653-660
pubmed: 29335825
IEEE Trans Med Imaging. 2017 Jun;36(6):1231-1249
pubmed: 28182555
J Am Coll Surg. 2012 Feb;214(2):214-30
pubmed: 22200377
Bus Horiz. 2014 Sep;57(5):571-582
pubmed: 25429161
Nat Med. 2020 Mar;26(3):364-373
pubmed: 32152583
Front Med. 2020 Aug;14(4):369-381
pubmed: 32621201
BMC Med Inform Decis Mak. 2008 Oct 27;8 Suppl 1:S2
pubmed: 19007439
Clin Chem Lab Med. 2019 Feb 25;57(3):308-311
pubmed: 29927745
Clin Chem. 1996 Jan;42(1):81-90
pubmed: 8565239
Int J Comput Assist Radiol Surg. 2015 Jun;10(6):749-59
pubmed: 25847671
NPJ Digit Med. 2018 Aug 28;1:39
pubmed: 31304320
BJU Int. 2020 Sep;126(3):350-358
pubmed: 32315504
Med Image Comput Comput Assist Interv. 2013;16(Pt 3):49-56
pubmed: 24505743
IEEE Trans Med Imaging. 2019 Apr;38(4):1069-1078
pubmed: 30371356
Int J Comput Assist Radiol Surg. 2019 Jun;14(6):1089-1095
pubmed: 30968352
Annu Rev Public Health. 2017 Mar 20;38:23-38
pubmed: 28125388
Int J Comput Assist Radiol Surg. 2018 Sep;13(9):1397-1408
pubmed: 30006820
Sci Data. 2020 Aug 28;7(1):283
pubmed: 32859981
IEEE Trans Biomed Eng. 2018 Nov;65(11):2649-2659
pubmed: 29993443
Int J Comput Assist Radiol Surg. 2016 Jun;11(6):909-17
pubmed: 27142459
Med Image Comput Comput Assist Interv. 2012;15(Pt 2):568-75
pubmed: 23286094
Ann Surg. 2008 Aug;248(2):189-98
pubmed: 18650627
Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):12592-12594
pubmed: 32457147
Chirurg. 2020 Jan;91(1):51-59
pubmed: 31654104
Int J Comput Assist Radiol Surg. 2014 May;9(3):495-511
pubmed: 24014322
Nature. 2020 Jan;577(7788):89-94
pubmed: 31894144
Sci Data. 2021 May 27;8(1):142
pubmed: 34045470
Med Image Anal. 2021 Jul;71:102058
pubmed: 33930829
Nat Biomed Eng. 2018 Oct;2(10):749-760
pubmed: 31001455
Int J Med Robot. 2009 Dec;5(4):423-34
pubmed: 19621334
J Am Coll Surg. 2011 May;212(5):873-9
pubmed: 21398154
Brief Bioinform. 2018 Nov 27;19(6):1236-1246
pubmed: 28481991
JAMA Surg. 2018 Aug 1;153(8):764-765
pubmed: 29617521
JAMA Surg. 2018 Sep 1;153(9):850-851
pubmed: 29617542
Nat Commun. 2020 Jul 22;11(1):3673
pubmed: 32699250
Int J Comput Assist Radiol Surg. 2017 Aug;12(8):1461-1469
pubmed: 28484922
IEEE Trans Med Imaging. 2017 Jul;36(7):1542-1549
pubmed: 28186883
Cureus. 2018 May 31;10(5):e2716
pubmed: 30079282
Int J Comput Assist Radiol Surg. 2019 Jun;14(6):1079-1087
pubmed: 30968355
Lancet Digit Health. 2019 Sep;1(5):e232-e242
pubmed: 33323271
NPJ Digit Med. 2019 Aug 20;2:79
pubmed: 31453374
JAMA Dermatol. 2019 Oct 01;155(10):1135-1141
pubmed: 31411641
Ann Surg Oncol. 2020 Mar;27(3):866-874
pubmed: 31696396
PLoS One. 2015 Jul 10;10(7):e0130140
pubmed: 26161953
Nature. 2016 Oct 27;538(7626):471-476
pubmed: 27732574
Radiology. 2018 May;287(2):398-412
pubmed: 29178816
Annu Rev Biomed Eng. 2017 Jun 21;19:301-325
pubmed: 28375649
Archit Rec. 2011;(8):67-71
pubmed: 21850818
Proc IEEE Inst Electr Electron Eng. 2020 Jan;108(1):198-214
pubmed: 31920208
Int J Comput Assist Radiol Surg. 2015 Aug;10(8):1201-12
pubmed: 25895078
Clin Ther. 2016 Apr;38(4):688-701
pubmed: 27130797
Ann Transl Med. 2020 Apr;8(7):434
pubmed: 32395478
Nat Med. 2019 Jan;25(1):44-56
pubmed: 30617339
Int J Med Inform. 2019 Mar;123:37-48
pubmed: 30654902
Ann Surg Open. 2020 Oct 05;1(2):e011
pubmed: 37637444
Surg Endosc. 2018 Apr;32(4):1636-1655
pubmed: 29442240
PLoS Med. 2018 Nov 27;15(11):e1002701
pubmed: 30481172
Int J Comput Assist Radiol Surg. 2018 Jun;13(6):925-933
pubmed: 29704196
Clin Epidemiol. 2018 Aug 10;10:961-970
pubmed: 30127646
Surg Endosc. 2020 Aug;34(8):3285-3288
pubmed: 32415370
JAMA. 2020 Jul 21;324(3):235-236
pubmed: 32134437
PLoS One. 2018 Jan 23;13(1):e0191628
pubmed: 29360840
Radiol Artif Intell. 2020 May 27;2(3):e190043
pubmed: 32510054
Eur Urol Focus. 2022 Mar;8(2):613-622
pubmed: 33941503
Updates Surg. 2021 Oct;73(5):2001-2007
pubmed: 33105017
Surg Endosc. 2021 Sep;35(9):5365-5374
pubmed: 33904989
Sci Rep. 2021 Feb 23;11(1):4343
pubmed: 33623058
Med Image Comput Comput Assist Interv. 2010;13(Pt 1):275-82
pubmed: 20879241
Med Image Comput Comput Assist Interv. 2010;13(Pt 1):77-85
pubmed: 20879217
IEEE Trans Med Imaging. 2015 Dec;34(12):2603-17
pubmed: 26625340
AMIA Annu Symp Proc. 2011;2011:472-80
pubmed: 22195101
Med Image Anal. 2020 Dec;66:101796
pubmed: 32911207
Int J Comput Assist Radiol Surg. 2020 Mar;15(3):379-387
pubmed: 31828502
Nature. 2019 Aug;572(7767):116-119
pubmed: 31367026
Med Image Anal. 2020 Jul;63:101699
pubmed: 32375102
IEEE Trans Biomed Eng. 2017 Feb;64(2):429-440
pubmed: 27164565
JAMA Surg. 2018 Jun 1;153(6):505-507
pubmed: 29617525
Eur J Surg Oncol. 2020 May;46(5):796-803
pubmed: 31924432
J Pathol Inform. 2015 Jun 23;6:37
pubmed: 26167381
BMJ. 2020 Mar 25;368:m689
pubmed: 32213531
Lancet Oncol. 2019 May;20(5):728-740
pubmed: 30952559
NPJ Digit Med. 2020 Apr 7;3:53
pubmed: 32285013
J Surg Oncol. 2020 Feb;121(2):357-364
pubmed: 31797378
Comput Methods Programs Biomed. 2021 Nov;212:106452
pubmed: 34688174

Auteurs

Lena Maier-Hein (L)

Division of Computer Assisted Medical Interventions (CAMI), German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Mathematics and Computer Science, Heidelberg University, Heidelberg, Germany; Medical Faculty, Heidelberg University, Heidelberg, Germany. Electronic address: l.maier-hein@dkfz-heidelberg.de.

Matthias Eisenmann (M)

Division of Computer Assisted Medical Interventions (CAMI), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Duygu Sarikaya (D)

Department of Computer Engineering, Faculty of Engineering, Gazi University, Ankara, Turkey; LTSI, Inserm UMR 1099, University of Rennes 1, Rennes, France.

Keno März (K)

Division of Computer Assisted Medical Interventions (CAMI), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Toby Collins (T)

IRCAD, Strasbourg, France.

Anand Malpani (A)

The Malone Center for Engineering in Healthcare, The Johns Hopkins University, Baltimore, Maryland, USA.

Johannes Fallert (J)

KARL STORZ SE & Co. KG, Tuttlingen, Germany.

Hubertus Feussner (H)

Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Stamatia Giannarou (S)

The Hamlyn Centre for Robotic Surgery, Imperial College London, London, United Kingdom.

Pietro Mascagni (P)

ICube, University of Strasbourg, CNRS, France; IHU Strasbourg, Strasbourg, France.

Hirenkumar Nakawala (H)

Altair Robotics Lab, University of Verona, Verona, Italy.

Adrian Park (A)

Department of Surgery, Anne Arundel Health System, Annapolis, Maryland, USA; Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Carla Pugh (C)

Department of Surgery, Stanford University School of Medicine, Stanford, California, USA.

Danail Stoyanov (D)

Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, United Kingdom.

Swaroop S Vedula (SS)

The Malone Center for Engineering in Healthcare, The Johns Hopkins University, Baltimore, Maryland, USA.

Kevin Cleary (K)

The Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, D.C., USA.

Gabor Fichtinger (G)

The Perk Lab, Queen's University, Kingston, Ontario, Canada.

Germain Forestier (G)

L'Institut de Recherche en Informatique, Mathématiques, Automatique et Signal (IRIMAS), University of Haute-Alsace, Mulhouse, France; Faculty of Information Technology, Monash University, Clayton, Victoria, Australia.

Bernard Gibaud (B)

LTSI, Inserm UMR 1099, University of Rennes 1, Rennes, France.

Teodor Grantcharov (T)

University of Toronto, Toronto, Ontario, Canada; The Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada.

Makoto Hashizume (M)

Kyushu University, Fukuoka, Japan; Kitakyushu Koga Hospital, Fukuoka, Japan.

Doreen Heckmann-Nötzel (D)

Division of Computer Assisted Medical Interventions (CAMI), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Hannes G Kenngott (HG)

Department for General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.

Ron Kikinis (R)

Department of Radiology, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.

Lars Mündermann (L)

KARL STORZ SE & Co. KG, Tuttlingen, Germany.

Nassir Navab (N)

Computer Aided Medical Procedures, Technical University of Munich, Munich, Germany; Department of Computer Science, The Johns Hopkins University, Baltimore, Maryland, USA.

Sinan Onogur (S)

Division of Computer Assisted Medical Interventions (CAMI), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Tobias Roß (T)

Division of Computer Assisted Medical Interventions (CAMI), German Cancer Research Center (DKFZ), Heidelberg, Germany; Medical Faculty, Heidelberg University, Heidelberg, Germany.

Raphael Sznitman (R)

ARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland.

Russell H Taylor (RH)

Department of Computer Science, The Johns Hopkins University, Baltimore, Maryland, USA.

Minu D Tizabi (MD)

Division of Computer Assisted Medical Interventions (CAMI), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Martin Wagner (M)

Department for General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.

Gregory D Hager (GD)

The Malone Center for Engineering in Healthcare, The Johns Hopkins University, Baltimore, Maryland, USA; Department of Computer Science, The Johns Hopkins University, Baltimore, Maryland, USA.

Thomas Neumuth (T)

Innovation Center Computer Assisted Surgery (ICCAS), University of Leipzig, Leipzig, Germany.

Nicolas Padoy (N)

ICube, University of Strasbourg, CNRS, France; IHU Strasbourg, Strasbourg, France.

Justin Collins (J)

Division of Surgery and Interventional Science, University College London, London, United Kingdom.

Ines Gockel (I)

Department of Visceral, Transplant, Thoracic and Vascular Surgery, Leipzig University Hospital, Leipzig, Germany.

Jan Goedeke (J)

Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany.

Daniel A Hashimoto (DA)

University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, Ohio, USA; Surgical AI and Innovation Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Luc Joyeux (L)

My FetUZ Fetal Research Center, Department of Development and Regeneration, Biomedical Sciences, KU Leuven, Leuven, Belgium; Center for Surgical Technologies, Faculty of Medicine, KU Leuven, Leuven, Belgium; Department of Obstetrics and Gynecology, Division Woman and Child, Fetal Medicine Unit, University Hospitals Leuven, Leuven, Belgium; Michael E. DeBakey Department of Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA.

Kyle Lam (K)

Department of Surgery and Cancer, Imperial College London, London, United Kingdom.

Daniel R Leff (DR)

Department of BioSurgery and Surgical Technology, Imperial College London, London, United Kingdom; Hamlyn Centre for Robotic Surgery, Imperial College London, London, United Kingdom; Breast Unit, Imperial Healthcare NHS Trust, London, United Kingdom.

Amin Madani (A)

Department of Surgery, University Health Network, Toronto, Ontario, Canada.

Hani J Marcus (HJ)

National Hospital for Neurology and Neurosurgery, and UCL Queen Square Institute of Neurology, London, United Kingdom.

Ozanan Meireles (O)

Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, USA.

Alexander Seitel (A)

Division of Computer Assisted Medical Interventions (CAMI), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Dogu Teber (D)

Department of Urology, City Hospital Karlsruhe, Karlsruhe, Germany.

Frank Ückert (F)

Institute for Applied Medical Informatics, Hamburg University Hospital, Hamburg, Germany.

Beat P Müller-Stich (BP)

Department for General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.

Pierre Jannin (P)

LTSI, Inserm UMR 1099, University of Rennes 1, Rennes, France.

Stefanie Speidel (S)

Division of Translational Surgical Oncology, National Center for Tumor Diseases (NCT/UCC) Dresden, Dresden, Germany; Centre for Tactile Internet with Human-in-the-Loop (CeTI), TU Dresden, Dresden, Germany.

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