An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria.

arab coronavirus disease 2019 (COVID-19) kawasaki disease multisystem inflammatory syndrome in children (MIS-C) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Journal

Avicenna journal of medicine
ISSN: 2231-0770
Titre abrégé: Avicenna J Med
Pays: Germany
ID NLM: 101584155

Informations de publication

Date de publication:
Oct 2021
Historique:
entrez: 9 12 2021
pubmed: 10 12 2021
medline: 10 12 2021
Statut: epublish

Résumé

Multisystem inflammatory syndrome in children (MIS-C) is a rare and critical condition that affects children following exposure to severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, leading to multiorgan dysfunction and shock. MIS-C has been reported from different parts of the world but rarely from Arab countries. In this report, we describe a 15-year-old Arab boy who was admitted to the ICU during the surge of Coronavirus transmission in Syria with a clinical picture consistent with MIS-C, including high-grade fever, gastrointestinal symptoms, rash, multiorgan dysfunction, and shock. Laboratory profile showed significant elevation of inflammatory markers, negative SARS-CoV-2 RT-PCR testing but positive serologic testing for SARS-CoV-2. The patient received intravenous immunoglobulins (IVIG) and glucocorticoids with remarkable cardiac improvement and significant alleviation in inflammatory markers. To our knowledge, this is the first reported case of MIS-C from Syria, which adds to the epidemiological data about this new syndrome.

Identifiants

pubmed: 34881206
doi: 10.1055/s-0041-1734387
pii: 210016
pmc: PMC8648403
doi:

Types de publication

Case Reports

Langues

eng

Pagination

221-224

Informations de copyright

Syrian American Medical Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Déclaration de conflit d'intérêts

Conflict of Interest None declared.

Références

Pediatrics. 2020 Jun;145(6):
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J Pediatric Infect Dis Soc. 2020 Dec 31;9(6):746-751
pubmed: 32924059
Lancet Infect Dis. 2020 Nov;20(11):e276-e288
pubmed: 32818434
JAMA. 2020 Jul 21;324(3):259-269
pubmed: 32511692
N Engl J Med. 2020 Jul 23;383(4):334-346
pubmed: 32598831

Auteurs

Jaafer Zaino (J)

Intensive Care Unit, Syrian Mouassat Association Hospital, Damascus, Syria.

Abdullah Bakri (A)

Intensive Care Unit, Syrian Mouassat Association Hospital, Damascus, Syria.

Amani Al Sayed Ahmad (A)

Intensive Care Unit, Syrian Mouassat Association Hospital, Damascus, Syria.

Ghadeer Hadba (G)

Intensive Care Unit, Syrian Mouassat Association Hospital, Damascus, Syria.

Classifications MeSH