Predictors of Lymph Node Metastasis in T1 Colorectal Cancer in Young Patients: Results from a National Cancer Registry.

colorectal cancer gastrointestinal malignancy young-onset

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
25 Nov 2021
Historique:
received: 04 08 2021
revised: 14 11 2021
accepted: 19 11 2021
entrez: 10 12 2021
pubmed: 11 12 2021
medline: 11 12 2021
Statut: epublish

Résumé

The objective of this study is to fill the knowledge gap by examining predictors of lymph node metastasis (LNM) in young patients, less than 45 years, using a national cancer registry. Methods: Patients diagnosed with T1 colorectal cancer were identified in the Surveillance, Epidemiology, and End Results registry. In total, 692 patients with T1 colorectal cancer were identified. Most tumors occurred in white race (77.7%), between 40 and 44 years of age (49.4%), with grade III tumor differentiation (59.8%) and 1 to 1.9 cm size (32.2%), and were left-sided tumors (61.1%). The overall rate of LNM was 22.5% (

Identifiants

pubmed: 34884212
pii: jcm10235511
doi: 10.3390/jcm10235511
pmc: PMC8658610
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Cancer. 2016 Mar 15;122(6):929-34
pubmed: 26808454
Gastroenterology. 2019 Mar;156(4):858-859
pubmed: 30776345
J Am Coll Surg. 2011 Sep;213(3):352-61
pubmed: 21737316
Br J Surg. 2003 Feb;90(2):205-14
pubmed: 12555297
Lancet. 2014 Apr 26;383(9927):1490-1502
pubmed: 24225001
Mayo Clin Proc. 2014 Feb;89(2):216-24
pubmed: 24393412
Tech Coloproctol. 2013 Dec;17(6):653-61
pubmed: 23460362
Oncologist. 2020 Mar;25(3):244-251
pubmed: 32162825
Cancer Causes Control. 2013 Mar;24(3):463-71
pubmed: 23296454
BMC Cancer. 2019 Aug 14;19(1):803
pubmed: 31412872
J Mol Diagn. 2014 Jan;16(1):116-26
pubmed: 24184227
Cancer J. 2011 Nov-Dec;17(6):405-15
pubmed: 22157284
PLoS One. 2012;7(9):e45357
pubmed: 23049789
J Clin Oncol. 2008 Dec 10;26(35):5783-8
pubmed: 18809606
World J Gastroenterol. 2016 Feb 7;22(5):1736-44
pubmed: 26855533
Int J Cancer. 1999 Apr 12;81(2):214-8
pubmed: 10188721
Ann Intern Med. 2002 Jul 16;137(2):129-31
pubmed: 12118971
J Cancer Epidemiol. 2019 Nov 11;2019:9841295
pubmed: 31827515
World J Surg. 2004 Jun;28(6):558-62
pubmed: 15366745
Surg Endosc. 2020 Sep;34(9):4030-4040
pubmed: 31620912
J Clin Gastroenterol. 2021 Jul 1;55(6):534-541
pubmed: 33464029
Anticancer Res. 2009 Jul;29(7):2727-37
pubmed: 19596953
J Gastroenterol. 2015 Jul;50(7):727-34
pubmed: 25725617
Cancer Med. 2020 Jul;9(14):5095-5113
pubmed: 32469151
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
J Clin Oncol. 2007 Dec 20;25(36):5808-14
pubmed: 18089879
J Natl Cancer Inst. 2008 Dec 3;100(23):1734-8
pubmed: 19033568
Gut. 2018 Feb;67(2):284-290
pubmed: 27811313

Auteurs

Daryl Ramai (D)

Division of Gastroenterology and Hepatology, University of Utah, Salt Lake City, UT 84132, USA.

Jameel Singh (J)

Department of Internal Medicine, Mathers Hospital, Port Jefferson, New York, NY 11777, USA.

Antonio Facciorusso (A)

Section of Gastroenterology, Department of Medical Sciences, University of Foggia, 71122 Foggia, Italy.

Saurabh Chandan (S)

Division of Gastroenterology & Hepatology, CHI Health Creighton University Medical Center, Omaha, NE 68124, USA.

Banreet Dhindsa (B)

Division of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE 68198, USA.

Amaninder Dhaliwal (A)

Division of Gastroenterology, Moffitt Cancer Center, University of South Florida, Tampa, FL 33612, USA.

Barbara Galassi (B)

Operative Unit of Medical Oncology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Gianluca Tomasello (G)

Operative Unit of Medical Oncology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Michele Ghidini (M)

Operative Unit of Medical Oncology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Classifications MeSH