Mechanisms, Characteristics, and Treatment of Neuropathic Pain and Peripheral Neuropathy Associated with Dinutuximab in Neuroblastoma Patients.
dinutuximab
molecular mechanisms
neuroblastoma
neuropathic pain
pediatric cancer
peripheral neuropathy
treatment
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
23 Nov 2021
23 Nov 2021
Historique:
received:
30
09
2021
revised:
13
11
2021
accepted:
18
11
2021
entrez:
10
12
2021
pubmed:
11
12
2021
medline:
24
12
2021
Statut:
epublish
Résumé
Prognosis of metastatic neuroblastoma is very poor. Its treatment includes induction chemotherapy, surgery, high-dose chemotherapy, radiotherapy, and maintenance with retinoic acid, associated with the anti-GD2 monoclonal antibody (ch14.18) dinutuximab. Immunotherapy determined a significant improvement in survival rate and is also utilized in relapsed and resistant neuroblastoma patients. Five courses of dinutuximab 100 mg/m
Identifiants
pubmed: 34884452
pii: ijms222312648
doi: 10.3390/ijms222312648
pmc: PMC8657961
pii:
doi:
Substances chimiques
Analgesics
0
Antibodies, Monoclonal
0
Gangliosides
0
sialogangliosides
0
Gabapentin
6CW7F3G59X
Morphine
76I7G6D29C
dinutuximab
7SQY4ZUD30
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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