Renal Safety Profile of EGFR Targeted Therapies: A Study from VigiBase

adverse drug effect anti-EGFR drugs pharmacovigilance renal toxicity

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
24 Nov 2021
Historique:
received: 21 09 2021
revised: 12 11 2021
accepted: 19 11 2021
entrez: 10 12 2021
pubmed: 11 12 2021
medline: 11 12 2021
Statut: epublish

Résumé

Kidney EGFR expression together with reported cases of glomerular diseases in the context of anti-EGFR drug administration raise concerns about the renal safety profile of these drugs. This issue is addressed in a case/non-case study carried out on VigiBase

Identifiants

pubmed: 34885014
pii: cancers13235907
doi: 10.3390/cancers13235907
pmc: PMC8657199
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Alexandre Crosnier (A)

Department of Pharmacology-Toxicology and Pharmacovigilance, University Hospital of Angers, 4 Rue Larrey, 49100 Angers, France.
Département de Médecine, Faculté de Médecine d'Angers, Université d'Angers, 49035 Angers, France.

Chadi Abbara (C)

Department of Pharmacology-Toxicology and Pharmacovigilance, University Hospital of Angers, 4 Rue Larrey, 49100 Angers, France.

Morgane Cellier (M)

Department of Pharmacology-Toxicology and Pharmacovigilance, University Hospital of Angers, 4 Rue Larrey, 49100 Angers, France.

Laurence Lagarce (L)

Department of Pharmacology-Toxicology and Pharmacovigilance, University Hospital of Angers, 4 Rue Larrey, 49100 Angers, France.

Marina Babin (M)

Department of Pharmacology-Toxicology and Pharmacovigilance, University Hospital of Angers, 4 Rue Larrey, 49100 Angers, France.

Delphine Bourneau-Martin (D)

Department of Pharmacology-Toxicology and Pharmacovigilance, University Hospital of Angers, 4 Rue Larrey, 49100 Angers, France.

Marie Briet (M)

Department of Pharmacology-Toxicology and Pharmacovigilance, University Hospital of Angers, 4 Rue Larrey, 49100 Angers, France.
Département de Médecine, Faculté de Médecine d'Angers, Université d'Angers, 49035 Angers, France.
Research Institute MitoVasc, UMR CNRS 6214 INSERM 1083, University of Angers, 49100 Angers, France.

Classifications MeSH