Cancer Influences the Elemental Composition of the Myocardium More Strongly than Conjugated Linoleic Acids-Chemometric Approach to Cardio-Oncological Studies.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
25 Nov 2021
Historique:
received: 14 10 2021
revised: 16 11 2021
accepted: 23 11 2021
entrez: 10 12 2021
pubmed: 11 12 2021
medline: 12 2 2022
Statut: epublish

Résumé

The aim of the study was to verify in a cardio-oncological model experiment if conjugated linoleic acids (CLA) fed to rats with mammary tumors affect the content of selected macro- and microelements in their myocardium. The diet of Sprague-Dawley females was supplemented either with CLA isomers or with safflower oil. In hearts of rats suffering from breast cancer, selected elements were analyzed with a quadrupole mass spectrometer with inductively coupled plasma ionization (ICP-MS). In order to better understand the data trends, cluster analysis, principal component analysis and linear discriminant analysis were applied. Mammary tumors influenced macro- and microelements content in the myocardium to a greater extent than applied diet supplementation. Significant influences of diet (

Identifiants

pubmed: 34885709
pii: molecules26237127
doi: 10.3390/molecules26237127
pmc: PMC8659207
pii:
doi:

Substances chimiques

Antioxidants 0
Linoleic Acids, Conjugated 0
Manganese 42Z2K6ZL8P
Copper 789U1901C5
Nickel 7OV03QG267
Selenium H6241UJ22B

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

Indian Heart J. 2016 Apr;68 Suppl 1:S77-85
pubmed: 27056658
Arch Anim Nutr. 2007 Apr;61(2):135-50
pubmed: 17451112
Biol Trace Elem Res. 2011 Jun;141(1-3):96-109
pubmed: 20495889
Nutrients. 2018 Dec 24;11(1):
pubmed: 30586919
Cancer Manag Res. 2018 Jan 10;10:69-79
pubmed: 29391828
Biochem Biophys Res Commun. 1994 Sep 15;203(2):1028-34
pubmed: 8093020
Caspian J Intern Med. 2018 Spring;9(2):134-139
pubmed: 29732030
Appl Spectrosc. 2012 Oct;66(10):1121-7
pubmed: 23031694
J Ayub Med Coll Abbottabad. 2012 Apr-Jun;24(2):62-4
pubmed: 24397055
Postepy Hig Med Dosw (Online). 2013 Jan 11;67:6-14
pubmed: 23475478
Lipids Health Dis. 2010 Nov 02;9:126
pubmed: 21044306
Prostaglandins Other Lipid Mediat. 2015 Jan-Mar;116-117:10-8
pubmed: 25448730
Biol Trace Elem Res. 2005 Feb;103(2):147-53
pubmed: 15772438
Biochim Biophys Acta. 2014 Nov;1842(11):2230-6
pubmed: 25201082
J Trace Elem Med Biol. 2017 Jan;39:36-42
pubmed: 27908421
J Trace Elem Med Biol. 2005;18(3):235-42
pubmed: 15966572
Breast. 2018 Dec;42:142-149
pubmed: 30296647
Eur Heart J. 1993 Jun;14(6):770-4
pubmed: 8325303
Biol Trace Elem Res. 1998 Jul;63(1):51-66
pubmed: 9764570
Bull Exp Biol Med. 2001 Jul;132(1):641-3
pubmed: 11687841
South Med J. 1991 Jul;84(7):891-5
pubmed: 2068634
Indian Heart J. 2017 Jul - Aug;69(4):556-562
pubmed: 28822531
J Physiol Biochem. 2014 Mar;70(1):27-32
pubmed: 23872882
Environ Sci Pollut Res Int. 2015 May;22(10):7930-5
pubmed: 25520207
J Am Coll Cardiol. 2018 Jun 26;71(25):2977-2981
pubmed: 29929621
Prostaglandins Leukot Essent Fatty Acids. 2016 Mar;106:1-10
pubmed: 26926361
Semin Oncol Nurs. 2017 Nov;33(4):384-392
pubmed: 28941563
Acta Pol Pharm. 2016 Mar-Apr;73(2):315-27
pubmed: 27180424
Nutr Cancer. 2015;67(1):145-55
pubmed: 25412117
Lancet Glob Health. 2019 Oct;7(10):e1332-e1345
pubmed: 31488387
Clin Nutr. 2019 Apr;38(2):800-805
pubmed: 29551406
Indian J Cancer. 2015 Jan-Mar;52(1):106-9
pubmed: 26837992
Hum Exp Toxicol. 1998 Apr;17(4):221-4
pubmed: 9617634
J Bone Miner Metab. 2011 May;29(3):268-78
pubmed: 20697754
Int J Clin Exp Med. 2015 Mar 15;8(3):3671-80
pubmed: 26064262
Nutrients. 2019 Aug 30;11(9):
pubmed: 31480307

Auteurs

Agnieszka Białek (A)

Department of Biotechnology and Nutrigenomics, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, Postępu 36A Jastrzębiec, 05-552 Magdalenka, Poland.

Małgorzata Białek (M)

Department of Animal Nutrition, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland.

Tomasz Lepionka (T)

Department of Bioaerosols, The Biological Threats Identification and Countermeasure Center of the General Karol Kaczkowski Military Institute of Hygiene and Epidemiology, Lubelska 4 St, 24-100 Puławy, Poland.

Anna Ruszczyńska (A)

Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Żwirki i Wigury 101, 02-089 Warsaw, Poland.

Ewa Bulska (E)

Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Żwirki i Wigury 101, 02-089 Warsaw, Poland.

Marian Czauderna (M)

Department of Animal Nutrition, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH