A link between mitotic defects and mitotic catastrophe: detection and cell fate.
Cancer
Cell death
DNA damage
Mitotic catastrophe
Senescence
Journal
Biology direct
ISSN: 1745-6150
Titre abrégé: Biol Direct
Pays: England
ID NLM: 101258412
Informations de publication
Date de publication:
09 12 2021
09 12 2021
Historique:
received:
06
11
2021
accepted:
14
11
2021
entrez:
10
12
2021
pubmed:
11
12
2021
medline:
14
1
2022
Statut:
epublish
Résumé
Although the phenomenon of mitotic catastrophe was first described more than 80 years ago, only recently has this term been used to explain a mechanism of cell death linked to delayed mitosis. Several mechanisms have been suggested for mitotic catastrophe development and cell fate. Depending on molecular perturbations, mitotic catastrophe can end in three types of cell death, namely apoptosis, necrosis, or autophagy. Moreover, mitotic catastrophe can be associated with different types of cell aging, the development of which negatively affects tumor elimination and, consequently, reduces the therapeutic effect. The effective triggering of mitotic catastrophe in clinical practice requires induction of DNA damage as well as inhibition of the molecular pathways that regulate cell cycle arrest and DNA repair. Here we discuss various methods to detect mitotic catastrophe, the mechanisms of its development, and the attempts to use this phenomenon in cancer treatment.
Identifiants
pubmed: 34886882
doi: 10.1186/s13062-021-00313-7
pii: 10.1186/s13062-021-00313-7
pmc: PMC8656038
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
25Informations de copyright
© 2021. The Author(s).
Références
Int J Biochem Cell Biol. 2018 Sep;102:101-108
pubmed: 30025878
Mol Cancer Ther. 2016 Jun;15(6):1332-43
pubmed: 27196784
Sci Rep. 2017 Nov 6;7(1):14571
pubmed: 29109414
Mol Cell. 2015 Nov 19;60(4):524-36
pubmed: 26590712
Blood. 2016 Feb 4;127(5):582-95
pubmed: 26563132
Cell Cycle. 2011 Aug 15;10(16):2763-9
pubmed: 21775823
Nat Rev Cancer. 2009 Jun;9(6):400-14
pubmed: 19440234
Mol Cancer Res. 2019 Dec;17(12):2457-2468
pubmed: 31551253
Mol Cancer Res. 2009 Mar;7(3):371-82
pubmed: 19276188
Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19108-13
pubmed: 19855003
EMBO J. 2010 Apr 7;29(7):1272-84
pubmed: 20186124
Cancer Cell. 2020 Feb 10;37(2):157-167.e6
pubmed: 32004442
Biochem Pharmacol. 2002 Sep;64(5-6):1007-9
pubmed: 12213599
Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3127-3132
pubmed: 28270606
Cell Stem Cell. 2018 Oct 4;23(4):544-556.e4
pubmed: 30244867
Genes Dev. 2017 Jan 1;31(1):34-45
pubmed: 28130345
EMBO J. 2010 Jul 21;29(14):2407-20
pubmed: 20526282
Br J Haematol. 2014 Jul;166(1):98-108
pubmed: 24684350
Science. 2021 Oct 29;374(6567):eabb3420
pubmed: 34709885
Cancer Res. 2010 May 1;70(9):3657-66
pubmed: 20406977
Oncogene. 2004 Apr 12;23(16):2825-37
pubmed: 15077146
Cell Death Differ. 2002 Dec;9(12):1287-93
pubmed: 12478465
Cancers (Basel). 2021 Jul 22;13(15):
pubmed: 34359573
Int J Radiat Biol. 2019 Sep;95(9):1205-1219
pubmed: 31287365
Am J Pathol. 1995 Apr;146(4):963-71
pubmed: 7717463
Oncotarget. 2017 Feb 21;8(8):12741-12753
pubmed: 28055975
Autophagy. 2008 Oct;4(7):949-51
pubmed: 18769111
Mol Cell. 2015 Mar 5;57(5):860-872
pubmed: 25702873
Drug Resist Updat. 2016 Jan;24:1-12
pubmed: 26830311
Dev Cell. 2020 Feb 10;52(3):335-349.e7
pubmed: 31983631
PLoS One. 2007 Dec 26;2(12):e1337
pubmed: 18159231
Drug Resist Updat. 2001 Oct;4(5):303-13
pubmed: 11991684
Oncogene. 2020 Jan;39(1):1-16
pubmed: 31462710
Interdiscip Top Gerontol. 2013;38:17-27
pubmed: 23503512
Curr Protoc Immunol. 2018 Feb 21;120:5.1.1-5.1.11
pubmed: 29512141
Cell Death Dis. 2010;1:e25
pubmed: 21364633
PLoS One. 2011;6(8):e22946
pubmed: 21853057
Int J Biochem Cell Biol. 2016 Dec;81(Pt A):133-136
pubmed: 27840153
Int J Mol Sci. 2019 Mar 11;20(5):
pubmed: 30862116
Trends Cell Biol. 2021 Sep;31(9):712-720
pubmed: 33752921
Mol Cell Oncol. 2017 Mar 10;4(3):e1299274
pubmed: 28616577
Cancer Cell. 2017 Jan 9;31(1):79-93
pubmed: 28073006
Oncogene. 2004 May 27;23(25):4353-61
pubmed: 15048074
Molecules. 2016 May 19;21(5):
pubmed: 27213315
Cold Spring Harb Perspect Biol. 2012 Jun 01;4(6):
pubmed: 22661635
Nature. 1999 Oct 7;401(6753):616-20
pubmed: 10524633
Cell Death Dis. 2018 Feb 2;9(2):142
pubmed: 29396391
Sci Rep. 2019 Dec 11;9(1):18882
pubmed: 31827119
Cell. 1986 Apr 11;45(1):145-53
pubmed: 3955656
Sci Rep. 2020 Jul 20;10(1):11997
pubmed: 32686724
Biotechniques. 2005 Dec;39(6 Suppl):S2-5
pubmed: 20158500
Oncogene. 2012 Mar 15;31(11):1408-18
pubmed: 21804608
Cell Death Dis. 2013 Apr 18;4:e603
pubmed: 23598415
J Cell Sci. 2016 May 1;129(9):1950
pubmed: 27134241
Front Genet. 2020 Sep 10;11:1036
pubmed: 33133138
Curr Biol. 2015 Oct 19;25(20):R1002-18
pubmed: 26485365
J Cell Sci. 2003 Jul 15;116(Pt 14):2987-98
pubmed: 12783991
Science. 2004 May 7;304(5672):843-6
pubmed: 15073321
Mol Cancer Ther. 2010 Feb;9(2):268-78
pubmed: 20124450
J Cell Biol. 2013 Mar 18;200(6):699-708
pubmed: 23479741
Cell Cycle. 2012 Nov 15;11(22):4147-51
pubmed: 23095636
Nat Rev Mol Cell Biol. 2011 Jun;12(6):385-92
pubmed: 21527953
Cancer Cell. 2017 Sep 11;32(3):342-359.e10
pubmed: 28898696
Cell. 2010 Mar 19;140(6):883-99
pubmed: 20303878
Cell Biol Int. 2005 Dec;29(12):1084-97
pubmed: 16316756
Nat Struct Mol Biol. 2010 Aug;17(8):982-9
pubmed: 20639885
Nat Commun. 2019 Nov 7;10(1):5065
pubmed: 31699977
Br J Radiol. 1952 Mar;25(293):235-44
pubmed: 14916100
J Cell Biol. 1998 Mar 23;140(6):1307-20
pubmed: 9508765
Oncogene. 2005 Jul 14;24(30):4765-77
pubmed: 15870702
Biochem Biophys Res Commun. 2020 Jan 29;522(1):144-150
pubmed: 31757415
Oncogene. 2009 Jan 15;28(2):170-83
pubmed: 18820706
Science. 2003 Jan 10;299(5604):214-5
pubmed: 12522239
Nat Rev Mol Cell Biol. 2007 May;8(5):379-93
pubmed: 17426725
Cancer Cell Int. 2006 Nov 08;6:25
pubmed: 17092342