Clinical performance in ERN eUROGEN for penile, testicular, adrenal and soft tissue cancers.

Adrenal tumours ERN eUROGEN European reference network Penile cancer Soft tissue cancer Testicular cancer

Journal

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
ISSN: 1532-2157
Titre abrégé: Eur J Surg Oncol
Pays: England
ID NLM: 8504356

Informations de publication

Date de publication:
Mar 2022
Historique:
received: 06 10 2021
accepted: 14 11 2021
pubmed: 12 12 2021
medline: 6 5 2022
entrez: 11 12 2021
Statut: ppublish

Résumé

European Reference Network (ERN) eUROGEN is a cross-border collaboration set up by the European Commission in 2017 aimed at tackling rare urogenital conditions, including cancers. This report aims to assess ERN eUROGEN's operational activity with a focus on rare urogenital cancers. Data for descriptive analyses were collected retrospectively between 2013 and 2017, and prospectively between 2018 and 2020. Operational indicators were set by the European Commission from 2018. Additionally, in 2019/20 centres self-assessed clinical service provision and provided clinical metrics for rare cancer specialist centres as established by experts. Results revealed that the cumulative rare urogenital cancer population increased 519.8% from 1,631 in 2013 to 10,109 in 2020. This may provide opportunities for research and creation of a large cancer registry. In total, ten centres met the clinical requirements for rare cancer specialist centres providing evidence of high-volume. Differences in data collection methods between centres limit further analyses. Other rare cancer data identified 39 panel discussions, three webinars, and eight publications. Whilst limitations to data analysis remain, ERN eUROGEN has demonstrated excellent operational performance with promising opportunities for rare cancer research.

Sections du résumé

BACKGROUND BACKGROUND
European Reference Network (ERN) eUROGEN is a cross-border collaboration set up by the European Commission in 2017 aimed at tackling rare urogenital conditions, including cancers.
OBJECTIVE OBJECTIVE
This report aims to assess ERN eUROGEN's operational activity with a focus on rare urogenital cancers.
DESIGN, SETTING AND PARTICIPANTS METHODS
Data for descriptive analyses were collected retrospectively between 2013 and 2017, and prospectively between 2018 and 2020.
OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS METHODS
Operational indicators were set by the European Commission from 2018. Additionally, in 2019/20 centres self-assessed clinical service provision and provided clinical metrics for rare cancer specialist centres as established by experts.
RESULTS AND LIMITATIONS CONCLUSIONS
Results revealed that the cumulative rare urogenital cancer population increased 519.8% from 1,631 in 2013 to 10,109 in 2020. This may provide opportunities for research and creation of a large cancer registry. In total, ten centres met the clinical requirements for rare cancer specialist centres providing evidence of high-volume. Differences in data collection methods between centres limit further analyses. Other rare cancer data identified 39 panel discussions, three webinars, and eight publications.
CONCLUSIONS CONCLUSIONS
Whilst limitations to data analysis remain, ERN eUROGEN has demonstrated excellent operational performance with promising opportunities for rare cancer research.

Identifiants

pubmed: 34893364
pii: S0748-7983(21)00819-2
doi: 10.1016/j.ejso.2021.11.014
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

680-686

Informations de copyright

Copyright © 2021 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Darren E. Shilhan, Michelle Battye, Hans Langenhuijsen and Wout F.J. Feitz report to be under employment of the European Union Connection Europe Facility grant permitted for the ERN eUROGEN coordination team and ERN eUROGEN Direct Grant.

Auteurs

Sophie Ashley (S)

Department of Urology, The Christie NHS Foundation Trust, Manchester, UK. Electronic address: sophie.ashley1@nhs.net.

Darren Shilhan (D)

Radboudumc, Nijmegen, the Netherlands.

Michelle Battye (M)

Radboudumc, Nijmegen, the Netherlands.

Christian Meyer (C)

University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Urology, Ruhr University Bochum, Klinikum, Herford, Germany.

Mariangela Mancini (M)

Urological Clinic Department of Surgical Oncological and Gastroenterological Sciences, University Hospital of Padova, Padova, Italy.

Benjamin Ayres (B)

Department of Urology, St George's University Hospitals NHS Trust, London, UK.

Asif Muneer (A)

NIHR Biomedical Research Centre UCLH and Division of Surgery and Interventional Science UCL, London, United Kingdom.

Maarten Albersen (M)

Universitair Ziekenhuis Leuven, Leuven, Belgium.

Wout Feitz (W)

Division of Pediatric Urology, Department of Urology, Radboudumc Amalia Children's Hospital, Nijmegen, the Netherlands.

Johan Ferdinand Langenhuijsen (JF)

Radboudumc, Nijmegen, the Netherlands.

Vijay Sangar (V)

Department of Urology, The Christie NHS Foundation Trust, Manchester, UK.

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