The protective role of vitamin C in the management of COVID-19: A Review.
COVID-19
Immunity
Pathogenesis of COVID-19
Vitamin C
Journal
The Journal of the Egyptian Public Health Association
ISSN: 0013-2446
Titre abrégé: J Egypt Public Health Assoc
Pays: United States
ID NLM: 7505602
Informations de publication
Date de publication:
11 Dec 2021
11 Dec 2021
Historique:
received:
27
10
2020
accepted:
13
11
2021
entrez:
11
12
2021
pubmed:
12
12
2021
medline:
12
12
2021
Statut:
epublish
Résumé
The outbreak of coronavirus infectious disease-2019 (COVID-19) is globally deemed a significant threat to human life. Researchers are searching for prevention strategies, mitigation interventions, and potential therapeutics that may reduce the infection's severity. One such means that is highly being talked in online and in social media is vitamin C. Vitamin C is a robust antioxidant that boosts the immune system of the human body. It helps in normal neutrophil function, scavenging of oxidative species, regeneration of vitamin E, modulation of signaling pathways, activation of pro-inflammatory transcription factors, activation of the signaling cascade, regulation of inflammatory mediators, and phagocytosis and increases neutrophil motility to the site of infection. All of these immunological functions are required for the prevention of COVID-19 infection. Considering the role of vitamin C, it would be imperative to administrate vitamin C for the management of severe COVID-19. However, there is no specific clinical data available to confirm the use of vitamin C in the current pandemic.
Sections du résumé
BACKGROUND
BACKGROUND
The outbreak of coronavirus infectious disease-2019 (COVID-19) is globally deemed a significant threat to human life. Researchers are searching for prevention strategies, mitigation interventions, and potential therapeutics that may reduce the infection's severity. One such means that is highly being talked in online and in social media is vitamin C.
MAIN TEXT
METHODS
Vitamin C is a robust antioxidant that boosts the immune system of the human body. It helps in normal neutrophil function, scavenging of oxidative species, regeneration of vitamin E, modulation of signaling pathways, activation of pro-inflammatory transcription factors, activation of the signaling cascade, regulation of inflammatory mediators, and phagocytosis and increases neutrophil motility to the site of infection. All of these immunological functions are required for the prevention of COVID-19 infection.
CONCLUSION
CONCLUSIONS
Considering the role of vitamin C, it would be imperative to administrate vitamin C for the management of severe COVID-19. However, there is no specific clinical data available to confirm the use of vitamin C in the current pandemic.
Identifiants
pubmed: 34894332
doi: 10.1186/s42506-021-00095-w
pii: 10.1186/s42506-021-00095-w
pmc: PMC8665316
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
33Informations de copyright
© 2021. The Author(s).
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