What Has Changed in the Management of Uterine Serous Carcinomas? Two Decades of Experience.
cancer
endometrial
p53 abnormal expression
survival
Journal
Current oncology (Toronto, Ont.)
ISSN: 1718-7729
Titre abrégé: Curr Oncol
Pays: Switzerland
ID NLM: 9502503
Informations de publication
Date de publication:
20 11 2021
20 11 2021
Historique:
received:
04
09
2021
revised:
09
11
2021
accepted:
17
11
2021
entrez:
13
12
2021
pubmed:
14
12
2021
medline:
24
3
2022
Statut:
epublish
Résumé
Uterine serous carcinoma accounts for 3-10% of endometrial cancers, but it is the most lethal histopathological subtype. The molecular characterization of endometrial carcinomas has allowed novel therapeutic approaches for these patients. We undertook a retrospective analysis of patients with uterine serous carcinomas treated in our hospital within the last two decades to identify possible changes in their management. The patients and their characteristics were evenly distributed across the two decades. Treatment modalities did not change significantly throughout this period. After adjuvant treatment, patients' median disease-free survival was 42.07 months (95% CI: 20.28-63.85), and it did not differ significantly between the two decades (
Identifiants
pubmed: 34898589
pii: curroncol28060410
doi: 10.3390/curroncol28060410
pmc: PMC8628752
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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