Late Effects After Haematopoietic Stem Cell Transplantation in ALL, Long-Term Follow-Up and Transition: A Step Into Adult Life.
ALL
adolescence
haematopoietic stem cell transplantation
late effects
long-term survivors
paediatric
quality of life
Journal
Frontiers in pediatrics
ISSN: 2296-2360
Titre abrégé: Front Pediatr
Pays: Switzerland
ID NLM: 101615492
Informations de publication
Date de publication:
2021
2021
Historique:
received:
10
09
2021
accepted:
19
10
2021
entrez:
13
12
2021
pubmed:
14
12
2021
medline:
14
12
2021
Statut:
epublish
Résumé
Haematopoietic stem cell transplant (HSCT) can be a curative treatment for children and adolescents with very-high-risk acute lymphoblastic leukaemia (ALL). Improvements in supportive care and transplant techniques have led to increasing numbers of long-term survivors worldwide. However, conditioning regimens as well as transplant-related complications are associated with severe sequelae, impacting patients' quality of life. It is widely recognised that paediatric HSCT survivors must have timely access to life-long care and surveillance in order to prevent, ameliorate and manage all possible adverse late effects of HSCT. This is fundamentally important because it can both prevent ill health and optimise the quality and experience of survival following HSCT. Furthermore, it reduces the impact of preventable chronic illness on already under-resourced health services. In addition to late effects, survivors of paediatric ALL also have to deal with unique challenges associated with transition to adult services. In this review, we: (1) provide an overview of the potential late effects following HSCT for ALL in childhood and adolescence; (2) focus on the unique challenges of transition from paediatric care to adult services; and (3) provide a framework for long-term surveillance and medical care for survivors of paediatric ALL who have undergone HSCT.
Identifiants
pubmed: 34900873
doi: 10.3389/fped.2021.773895
pmc: PMC8652149
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
773895Informations de copyright
Copyright © 2021 Diesch-Furlanetto, Gabriel, Zajac-Spychala, Cattoni, Hoeben and Balduzzi.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer GL declared a past collaboration with one of the authors TD-F to the handling Editor.
Références
J Androl. 1994 Nov-Dec;15(6):608-13
pubmed: 7721664
Bone Marrow Transplant. 2018 Jul;53(7):863-872
pubmed: 29382955
Front Biosci. 2001 Aug 01;6:G17-22
pubmed: 11487479
Br J Cancer. 2000 May;82(10):1636-45
pubmed: 10817497
Gen Comp Endocrinol. 2008 May 1;156(3):613-21
pubmed: 18358475
Child Care Health Dev. 2015 Jul;41(4):547-58
pubmed: 25351414
Biol Blood Marrow Transplant. 2017 Sep;23(9):1422-1428
pubmed: 28533057
Med Pediatr Oncol. 1999 Jul;33(1):2-8
pubmed: 10401490
Biol Blood Marrow Transplant. 2014 Apr;20(4):587-92
pubmed: 24388803
J Adolesc Health. 1995 Jul;17(1):3-5
pubmed: 7578159
Pediatr Blood Cancer. 2007 Aug;49(2):117-26
pubmed: 17029246
Am J Hematol. 1993 Jan;42(1):81-5
pubmed: 8416302
Cancer Nurs. 2014 Sep-Oct;37(5):E23-31
pubmed: 24145251
J Ocul Pharmacol Ther. 2016 Jun;32(5):296-303
pubmed: 27008099
Child Care Health Dev. 2011 Nov;37(6):883-95
pubmed: 22007989
J Pediatr Psychol. 2017 Oct 1;42(9):983-994
pubmed: 29046041
Biol Blood Marrow Transplant. 2011 Nov;17(11):1573-84
pubmed: 21963877
Expert Rev Pharmacoecon Outcomes Res. 2013 Apr;13(2):217-25
pubmed: 23570432
Bone Marrow Transplant. 2009 Sep;44(6):339-43
pubmed: 19308039
Int J Hematol. 2016 Jul;104(1):110-6
pubmed: 27084256
Blood. 2009 Jul 2;114(1):181-6
pubmed: 19414861
Blood. 2010 Oct 28;116(17):3129-39; quiz 3377
pubmed: 20656930
J Clin Oncol. 2018 Jan 1;36(1):44-52
pubmed: 29095680
J Adolesc Health. 2003 Oct;33(4):309-11
pubmed: 14519573
J Psychiatry Neurosci. 2015 Sep;40(5):291-3
pubmed: 26290063
Biol Blood Marrow Transplant. 2012 Mar;18(3):348-71
pubmed: 22178693
Bone Marrow Transplant. 2002 Mar;29(5):425-34
pubmed: 11919733
Paediatr Respir Rev. 2010 Jun;11(2):115-22
pubmed: 20416548
Semin Hematol. 2005 Apr;42(2 Suppl 1):S14-8
pubmed: 15846580
Ann Intern Med. 1991 Dec 15;115(12):925-30
pubmed: 1952488
Biol Blood Marrow Transplant. 2007 Jun;13(6):683-90
pubmed: 17531778
N Engl J Med. 2006 Apr 27;354(17):1813-26
pubmed: 16641398
J Clin Oncol. 1990 Feb;8(2):304-12
pubmed: 2299373
Mol Clin Oncol. 2020 Jun;12(6):574-580
pubmed: 32337040
Clin Infect Dis. 2001 Jan 15;32(2):214-9
pubmed: 11170910
J Pediatr. 1997 Feb;130(2):210-6
pubmed: 9042122
Haematologica. 2014 Oct;99(10):1632-7
pubmed: 24997153
Blood. 1997 Aug 1;90(3):994-8
pubmed: 9242528
Bone Marrow Transplant. 2005 May;35(10):991-5
pubmed: 15806126
J Adolesc Young Adult Oncol. 2013 Sep;2(3):104-11
pubmed: 26812188
J Clin Endocrinol Metab. 2018 Aug 1;103(8):2761-2784
pubmed: 29982476
Biol Blood Marrow Transplant. 2018 Jul;24(7):1415-1423
pubmed: 29496562
Blood. 2003 Nov 15;102(10):3822-8
pubmed: 12869516
Blood. 1996 Apr 1;87(7):3045-52
pubmed: 8639928
Bone Marrow Transplant. 2008 Oct;42(7):461-7
pubmed: 18604240
Bone Marrow Transplant. 1996 Jan;17(1):5-11
pubmed: 8673055
Blood. 2011 Apr 28;117(17):4442-8
pubmed: 21278355
Am J Kidney Dis. 2005 Apr;45(4):780-5
pubmed: 15806483
Int J Cancer. 2001;96 Suppl:117-24
pubmed: 11992395
Klin Padiatr. 2013 May;225(3):120-6
pubmed: 23716272
Biol Blood Marrow Transplant. 2014 Jun;20(6):794-800
pubmed: 24565992
Bone Marrow Transplant. 1995 Jun;15(6):873-7
pubmed: 7581084
Arch Ophthalmol. 1994 Mar;112(3):372-9
pubmed: 8129664
Bone Marrow Transplant. 2001 Feb;27(3):319-27
pubmed: 11277181
Curr Diabetes Rev. 2015;11(3):144-54
pubmed: 25824238
J Clin Oncol. 2009 May 10;27(14):2374-81
pubmed: 19364956
Biol Blood Marrow Transplant. 2016 May;22(5):782-95
pubmed: 26802323
J Pediatr. 1996 Oct;129(4):544-50
pubmed: 8859261
Biol Blood Marrow Transplant. 2019 Sep;25(9):1786-1791
pubmed: 31082473
Clin Endocrinol (Oxf). 2015 Jan;82(1):59-67
pubmed: 25132503
Pediatr Blood Cancer. 2017 Oct;64(10):
pubmed: 28383822
J Cancer Surviv. 2012 Sep;6(3):260-9
pubmed: 22547096
Health Expect. 2015 Dec;18(6):1941-55
pubmed: 25052198
Am J Ophthalmol. 1991 Dec 15;112(6):635-46
pubmed: 1957898
Pediatr Blood Cancer. 2017 Feb;64(2):346-352
pubmed: 27463688
Lancet Oncol. 2019 Mar;20(3):e155-e166
pubmed: 30842059
Pediatr Clin North Am. 2015 Feb;62(1):275-300
pubmed: 25435123
Biol Blood Marrow Transplant. 2009 Jul;15(7):817-26
pubmed: 19539213
Ophthalmology. 1991 Aug;98(8):1294-301
pubmed: 1923369
Bone Marrow Transplant. 2000 Jan;25(2):191-6
pubmed: 10673679
Bone Marrow Transplant. 2008 Jan;41(2):97
pubmed: 18231112
Clin Endocrinol (Oxf). 2019 Nov;91(5):624-632
pubmed: 31295360
Best Pract Res Clin Obstet Gynaecol. 2018 Apr;48:147-157
pubmed: 29221705
Blood. 2014 Jul 17;124(3):374-84
pubmed: 24914139
Free Radic Biol Med. 1997;22(7):1159-63
pubmed: 9098089
Biol Blood Marrow Transplant. 2008 Nov;14(11):1217-25
pubmed: 18940675
Cancer. 2014 Feb 15;120(4):469-79
pubmed: 24166350
Hum Reprod. 2018 Jul 1;33(7):1281-1290
pubmed: 29912328
Bone Marrow Transplant. 1996 Jan;17(1):63-6
pubmed: 8673057
PLoS One. 2018 Oct 16;13(10):e0204914
pubmed: 30325953
Cancer. 1992 Dec 1;70(11):2703-12
pubmed: 1423201
Bone Marrow Transplant. 2010 Jan;45(1):79-85
pubmed: 19421172
J Adolesc Young Adult Oncol. 2017 Mar;6(1):111-119
pubmed: 27486707
J Adolesc Health. 2017 Feb;60(2):147-153
pubmed: 28270337
Magn Reson Med. 2017 Jul;78(1):264-270
pubmed: 27509836
Biol Blood Marrow Transplant. 2008 Jul;14(7):790-4
pubmed: 18541198
Diabetes Care. 2012 Aug;35(8):1716-22
pubmed: 22699289
Bone Marrow Transplant. 2004 Jan;33(2):205-10
pubmed: 14628079
Pediatr Nephrol. 2002 Dec;17(12):1032-7
pubmed: 12478353
Bone Marrow Transplant. 2012 Aug;47(8):1067-74
pubmed: 22158389
Cancer Treat Rev. 2003 Oct;29(5):417-30
pubmed: 12972360
Haematologica. 1995 Jul-Aug;80(4):300-4
pubmed: 7590497
Medicine (Baltimore). 2007 Jul;86(4):215-224
pubmed: 17632263
Cancer. 2002 Sep 1;95(5):1076-84
pubmed: 12209694
J Cancer Surviv. 2021 Feb;15(1):151-162
pubmed: 32676793
Bone Marrow Transplant. 1996 Dec;18(6):1049-55
pubmed: 8971372
Int J Radiat Oncol Biol Phys. 2019 Jun 1;104(2):415-424
pubmed: 30769174
Biol Blood Marrow Transplant. 2015 Feb;21(2):225-32
pubmed: 24999225
Bone Marrow Transplant. 2012 Nov;47(11):1470-3
pubmed: 22484321
Haematologica. 2016 Jun;101(6):747-56
pubmed: 26969082
Blood. 1999 Jun 15;93(12):4109-15
pubmed: 10361107
Bone Marrow Transplant. 2006 Dec;38(12):799-805
pubmed: 17075568
Med Pediatr Oncol. 1985;13(4):165-72
pubmed: 3892260
J Adolesc Health. 1993 Nov;14(7):570-6
pubmed: 8312295
Bone Marrow Transplant. 1997 May;19(10):1019-22
pubmed: 9169646
Pediatrics. 2002 Dec;110(6 Pt 2):1304-6
pubmed: 12456949
Br J Haematol. 1997 Aug;98(2):453-7
pubmed: 9266950
Ann Hematol. 2013 Aug;92(8):1121-8
pubmed: 23604429
Biol Blood Marrow Transplant. 2010 Aug;16(8):1138-44
pubmed: 20197101
Sci Rep. 2020 Jul 30;10(1):12892
pubmed: 32733066
Pediatr Blood Cancer. 2020 Apr;67(4):e28137
pubmed: 31889398
Lancet Haematol. 2018 May;5(5):e184-e185
pubmed: 29628398
N Engl J Med. 2015 Oct 15;373(16):1541-52
pubmed: 26465987
Bone Marrow Transplant. 2016 Jan;51(1):89-95
pubmed: 26367238
Psychooncology. 2010 Sep;19(9):982-90
pubmed: 20017115
Brain Cogn. 2010 Feb;72(1):160-4
pubmed: 19963311
J Clin Oncol. 1997 Jun;15(6):2238-46
pubmed: 9196136
Cancer. 2009 Sep 15;115(18):4127-35
pubmed: 19536905
Fertil Steril. 2019 Dec;112(6):1022-1033
pubmed: 31843073
Biol Blood Marrow Transplant. 2017 Feb;23(2):201-210
pubmed: 27590105
Acta Endocrinol (Copenh). 1993 Jun;128(6):508-12
pubmed: 8337919
Bone Marrow Transplant. 2016 Nov;51(11):1482-1489
pubmed: 27348540
J Clin Oncol. 2007 Jun 10;25(17):2449-54
pubmed: 17557958
Bone Marrow Transplant. 2002 Oct;30(7):447-51
pubmed: 12368957
Asia Pac J Clin Oncol. 2017 Dec;13(6):407-415
pubmed: 28670761
JAMA. 2009 Jul 15;302(3):306-14
pubmed: 19602690
Haematologica. 2013 Jul;98(7):1089-97
pubmed: 23645686
J Clin Oncol. 2021 Feb 1;39(4):295-307
pubmed: 33332189
Bone Marrow Transplant. 2014 May;49(5):709-16
pubmed: 24535128
Blood. 2005 Feb 1;105(3):1348-54
pubmed: 15454481
Haematologica. 2006 Aug;91(8):1096-9
pubmed: 16885050
Biol Blood Marrow Transplant. 2017 Aug;23(8):1327-1334
pubmed: 28461213
Biol Blood Marrow Transplant. 2006 Feb;12(2):138-51
pubmed: 16443512
J Pediatr Oncol Nurs. 2017 Jan/Feb;34(1):20-27
pubmed: 26968661
Psychooncology. 2013 Sep;22(9):2039-45
pubmed: 23401266
Ophthalmology. 2009 Sep;116(9):1624-9
pubmed: 19729097
Pediatr Hematol Oncol. 2019 Nov;36(8):494-503
pubmed: 31633441
Support Care Cancer. 2018 Aug;26(8):2743-2750
pubmed: 29500581
J Clin Oncol. 2015 Sep 20;33(27):2938-48
pubmed: 26304874
Graefes Arch Clin Exp Ophthalmol. 2015 Aug;253(8):1397-402
pubmed: 25708560
Pediatr Blood Cancer. 2009 Jul;52(7):838-41
pubmed: 19229973
J Pediatr Hematol Oncol. 2017 Oct;39(7):e377-e380
pubmed: 28085750
Bone Marrow Transplant. 1997 Dec;20(12):1069-74
pubmed: 9466280
Free Radic Biol Med. 1995 Mar;18(3):383-9
pubmed: 9101228
Cornea. 2015 Mar;34(3):243-7
pubmed: 25603230
Bone Marrow Transplant. 2006 Sep;38(6):427-32
pubmed: 16878146
Semin Oncol Nurs. 2020 Feb;36(1):150983
pubmed: 31959510
Biol Blood Marrow Transplant. 2010 Jan;16(1):115-22
pubmed: 19766730
J Pediatr Psychol. 2012 Jan-Feb;37(1):85-96
pubmed: 21878430
Bone Marrow Transplant. 2007 Jun;39(11):667-75
pubmed: 17401396
Bone Marrow Transplant. 2012 May;47(5):684-93
pubmed: 21725370
Pediatr Blood Cancer. 2007 Dec;49(7):958-63
pubmed: 17474113
Blood. 2012 Nov 29;120(23):4505-12
pubmed: 23034279
Cornea. 2007 Sep;26(8):903-6
pubmed: 17721285
Bone Marrow Transplant. 2004 May;33(9):949-53
pubmed: 15004542
Blood. 2009 Jan 8;113(2):306-8
pubmed: 18838614
JAMA. 2002 Dec 4;288(21):2709-16
pubmed: 12460094
Pediatr Blood Cancer. 2019 Aug;66(8):e27793
pubmed: 31099145
Int J Infect Dis. 2010 Sep;14 Suppl 3:e104-7
pubmed: 20307998
Cancer Metastasis Rev. 2020 Mar;39(1):69-78
pubmed: 31980968
Pediatr Res. 2006 Feb;59(2):259-64
pubmed: 16439589
Am J Med. 1982 Nov;73(5):688-94
pubmed: 6753576
N Engl J Med. 2003 Jul 31;349(5):423-6
pubmed: 12890840
Acta Paediatr. 2000 Jul;89(7):814-9
pubmed: 10943964
Pediatrics. 2008 Mar;121(3):e705-13
pubmed: 18310191
Transplantation. 2003 Aug 27;76(4):673-8
pubmed: 12973107
Bone Marrow Transplant. 1996 Jun;17(6):1105-11
pubmed: 8807122
Cancer. 1981 Jun 1;47(11):2704-11
pubmed: 7260863
Int J Radiat Oncol Biol Phys. 2008 Apr 1;70(5):1343-9
pubmed: 18164830
N Engl J Med. 1983 May 5;308(18):1101
pubmed: 6339934
Bone Marrow Transplant. 2003 Jun;31(12):1151-6
pubmed: 12796795
Br J Haematol. 2018 Oct;183(1):104-109
pubmed: 30028016
Eye (Lond). 2017 Oct;31(10):1417-1426
pubmed: 28524885
Int J Radiat Oncol Biol Phys. 1998 Jun 1;41(3):659-68
pubmed: 9635717
Cancer Biol Ther. 2008 Oct;7(10):1533-9
pubmed: 18927494
N Engl J Med. 1997 Jul 3;337(1):8-14
pubmed: 9203425
Med Pediatr Oncol. 2001 Feb;36(2):295-304
pubmed: 11452938
Curr Treat Options Oncol. 2016 Sep;17(9):50
pubmed: 27476159
Blood Rev. 2021 Jan;45:100730
pubmed: 32654893
Int J Radiat Oncol Biol Phys. 2015 Jan 1;91(1):22-9
pubmed: 25227496
J Endocrinol Invest. 2020 Feb;43(2):209-217
pubmed: 31452114
Hemasphere. 2021 Mar 09;5(4):e544
pubmed: 33718802
Br J Haematol. 2015 Feb;168(4):518-25
pubmed: 25284463
Biol Blood Marrow Transplant. 2015 Mar;21(3):389-401.e1
pubmed: 25529383
Biol Blood Marrow Transplant. 2000;6(2A):165-74
pubmed: 10816024
Biol Blood Marrow Transplant. 2015 Oct;21(10):1707-13
pubmed: 26172477
Bone Marrow Transplant. 2004 Feb;33(4):435-41
pubmed: 14716354
JAMA Pediatr. 2013 Oct;167(10):939-46
pubmed: 23959392
Biol Blood Marrow Transplant. 2006 May;12(5):506-10
pubmed: 16635785
Bone Marrow Transplant. 2012 Feb;47(2):271-6
pubmed: 21478918
Biol Blood Marrow Transplant. 2011 Dec;17(12):1725-38
pubmed: 22005649
Biol Blood Marrow Transplant. 2008 Nov;14(11):1239-44
pubmed: 18940678
Fertil Steril. 2011 Jul;96(1):126-133.e3
pubmed: 21550046
J AAPOS. 2005 Oct;9(5):426-32
pubmed: 16213391
Diabetes Metab Res Rev. 2018 Oct;34(7):e3042
pubmed: 29931823
Int J Radiat Oncol Biol Phys. 2006 Jul 15;65(4):1228-32
pubmed: 16682132
Bone Marrow Transplant. 2020 Oct;55(10):1918-1927
pubmed: 31996791
Horm Res. 2003;59 Suppl 1:1-11
pubmed: 12566714
Am J Kidney Dis. 2002 Feb;39(2 Suppl 1):S1-266
pubmed: 11904577
Bone Marrow Transplant. 2008 Jun;41(12):997-1003
pubmed: 18438425
Clin Exp Ophthalmol. 2001 Aug;29(4):225-9
pubmed: 11545420
Semin Hematol. 2012 Jan;49(1):73-82
pubmed: 22221787
N Engl J Med. 2011 Feb 17;364(7):689-90
pubmed: 21323563
Bone Marrow Transplant. 2007 Jul;40(1):29-35
pubmed: 17468769
Bone Marrow Transplant. 1998 Jul;22(1):87-90
pubmed: 9678801
Bone Marrow Transplant. 2016 Feb;51(2):176-81
pubmed: 26642340
Blood. 2007 Feb 15;109(4):1765-72
pubmed: 17047152
Clin Infect Dis. 2014 Jun;58(12):1700-6
pubmed: 24700657
Pediatr Clin North Am. 2010 Feb;57(1):297-322
pubmed: 20307722
Cancer. 2018 Apr 1;124(7):1507-1515
pubmed: 29315507
Leukemia. 2018 Oct;32(10):2167-2177
pubmed: 29550834
Pediatr Blood Cancer. 2009 Aug;53(2):197-202
pubmed: 19353620
Blood. 2009 Aug 6;114(6):1270-5
pubmed: 19401560
J Pediatr Oncol Nurs. 2016 Mar-Apr;33(2):111-8
pubmed: 26206471
Pediatr Blood Cancer. 2018 Apr;65(4):
pubmed: 29286549
Pediatr Blood Cancer. 2017 Nov;64(11):
pubmed: 28557375
Biol Blood Marrow Transplant. 2010 Jan;16(1 Suppl):S90-6
pubmed: 19782145
Bone Marrow Transplant. 2012 May;47(5):619-25
pubmed: 21643022
Bone Marrow Transplant. 2021 Jun;56(6):1422-1425
pubmed: 33454725