Endostatin in Renal and Cardiovascular Diseases.

Angiogenesis Cardiovascular diseases Collagen XVIII Endostatin Renal diseases

Journal

Kidney diseases (Basel, Switzerland)
ISSN: 2296-9381
Titre abrégé: Kidney Dis (Basel)
Pays: Switzerland
ID NLM: 101658365

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 01 03 2021
accepted: 29 06 2021
entrez: 13 12 2021
pubmed: 14 12 2021
medline: 14 12 2021
Statut: epublish

Résumé

Endostatin, a protein derived from the cleavage of collagen XVIII by the action of proteases, is an endogenous inhibitor known for its ability to inhibit proliferation and migration of endothelial cells, angiogenesis, and tumor growth. Angiogenesis is defined as the formation of new blood vessels from pre-existing vasculature, which is crucial in many physiological processes, such as embryogenesis, tissue regeneration, and neoplasia. Increasing evidence shows that dysregulation of angiogenesis is crucial for the pathogenesis of renal and cardiovascular diseases. Endostatin plays a pivotal role in the regulation of angiogenesis. Recent studies have provided evidence that circulating endostatin increases significantly in patients with kidney and heart failure and may also contribute to disease progression. In the current review, we summarize the latest findings on preclinical and clinical studies analyzing the impact of endostatin on renal and cardiovascular diseases.

Identifiants

pubmed: 34901193
doi: 10.1159/000518221
pii: kdd-0007-0468
pmc: PMC8613550
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

468-481

Informations de copyright

Copyright © 2021 by S. Karger AG, Basel.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

Ann Thorac Surg. 2012 Nov;94(5):1509-17
pubmed: 22795062
J Nephrol. 2008 Sep-Oct;21(5):753-60
pubmed: 18949731
Adv Clin Exp Med. 2015 Nov-Dec;24(6):987-94
pubmed: 26771970
Am J Nephrol. 2012;35(4):335-40
pubmed: 22456114
Cell. 1997 Jan 24;88(2):277-85
pubmed: 9008168
Am J Respir Crit Care Med. 2015 Jan 15;191(2):208-18
pubmed: 25489667
Adv Med Sci. 2009;54(2):199-202
pubmed: 19758969
J Mol Biol. 2000 Sep 1;301(5):1179-90
pubmed: 10966814
Kidney Int. 2016 Jun;89(6):1281-92
pubmed: 27165830
J Int Med Res. 2020 Jul;48(7):300060520940856
pubmed: 32691651
Am J Physiol Heart Circ Physiol. 2014 Jun 15;306(12):H1692-9
pubmed: 24727495
Int J Mol Sci. 2018 Jun 24;19(7):
pubmed: 29937525
J Am Soc Nephrol. 2010 Sep;21(9):1445-55
pubmed: 20616167
J Zhejiang Univ Sci B. 2017 Nov.;18(11):994-1001
pubmed: 29119737
Cancer Lett. 2011 Feb 28;301(2):212-20
pubmed: 21216091
Arterioscler Thromb Vasc Biol. 2003 Feb 1;23(2):168-75
pubmed: 12588755
Mol Cell. 2001 Apr;7(4):811-22
pubmed: 11336704
J Atheroscler Thromb. 2015;22(10):1100-12
pubmed: 26016418
EMBO J. 1999 Aug 16;18(16):4414-23
pubmed: 10449407
Br J Cancer. 2005 Jan 17;92(1):89-93
pubmed: 15545970
J Biol Chem. 1995 Mar 3;270(9):4705-11
pubmed: 7876242
Arch Dermatol Res. 2006 Apr;297(10):433-8
pubmed: 16528552
EMBO J. 1999 Nov 15;18(22):6240-8
pubmed: 10562536
Afr Health Sci. 2016 Jun;16(2):542-53
pubmed: 27605970
EMBO J. 1998 Aug 3;17(15):4249-56
pubmed: 9687493
Am J Nephrol. 2020;51(5):373-380
pubmed: 32320989
Eur J Clin Invest. 2014 Feb;44(2):125-35
pubmed: 24188329
PLoS One. 2019 Aug 12;14(8):e0220935
pubmed: 31404120
EMBO J. 2002 Apr 2;21(7):1535-44
pubmed: 11927538
Eur J Intern Med. 2016 Sep;33:81-7
pubmed: 27394925
Acta Anaesthesiol Scand. 2017 Nov;61(10):1286-1295
pubmed: 28857121
Respir Res. 2013 May 20;14(1):56
pubmed: 23688086
Exp Cell Res. 2005 Jul 15;307(2):292-304
pubmed: 15950618
Int J Nanomedicine. 2015 May 28;10:3791-802
pubmed: 26060399
Braz J Med Biol Res. 2009 Dec;42(12):1150-5
pubmed: 19893988
FEBS Lett. 2000 Dec 15;486(3):247-51
pubmed: 11119712
Medicine (Baltimore). 2016 Aug;95(33):e4524
pubmed: 27537575
Int J Mol Sci. 2018 Mar 06;19(3):
pubmed: 29509663
Nan Fang Yi Ke Da Xue Xue Bao. 2008 Jun;28(6):930-2
pubmed: 18583230
Int J Cancer. 2018 May 15;142(10):2130-2138
pubmed: 29238974
Br J Cancer. 2014 Oct 14;111(8):1605-13
pubmed: 25137019
Am J Cardiol. 2007 Feb 15;99(4):494-8
pubmed: 17293192
Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4766-71
pubmed: 12682293
Kidney Int. 2007 Feb;71(3):227-38
pubmed: 17191085
J Biol Chem. 1994 May 13;269(19):13929-35
pubmed: 8188673
Cancer Res. 2002 Oct 1;62(19):5580-9
pubmed: 12359771
Curr Opin Nephrol Hypertens. 2009 Mar;18(2):160-5
pubmed: 19430335
Eur Heart J. 2015 Oct 7;36(38):2555-64
pubmed: 26142467
Matrix Biol. 2011 Mar;30(2):83-92
pubmed: 21163348
Biomed Res Int. 2017;2017:5724069
pubmed: 28835895
Am J Nephrol. 2014;40(5):417-24
pubmed: 25401956
Protein Pept Lett. 2012 Sep;19(9):969-74
pubmed: 22512651
Ren Fail. 2008;30(2):215-7
pubmed: 18300124
PLoS One. 2014 Apr 23;9(4):e96117
pubmed: 24759991
Cancer Lett. 2015 Apr 1;359(1):148-54
pubmed: 25597785
Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1024-9
pubmed: 11158588
FASEB J. 2002 Nov;16(13):1802-4
pubmed: 12354694
J Biol Chem. 1999 Apr 23;274(17):11721-6
pubmed: 10206987
Blood. 2007 Oct 15;110(8):2899-906
pubmed: 17615292
Diabetes Metab. 2016 Nov;42(5):351-357
pubmed: 27080454
Arq Bras Cardiol. 2017 Nov;109(5):448-456
pubmed: 28977054
Br J Cancer. 2005 Oct 31;93(9):1024-8
pubmed: 16234817
Pharmacol Rev. 2000 Jun;52(2):237-68
pubmed: 10835101
Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8763-7
pubmed: 7568013
Int J Cardiol. 2016 Jun 1;212:364-8
pubmed: 27057957
Zhonghua Yi Xue Za Zhi. 2001 Jun 25;81(12):726-9
pubmed: 11798955
FEBS Lett. 2008 Jul 23;582(17):2515-20
pubmed: 18570894
Clin Oncol (R Coll Radiol). 2013 May;25(5):308-17
pubmed: 23290342
Arch Physiol Biochem. 2010 May;116(2):63-72
pubmed: 20230216
J Biol Chem. 2009 Aug 14;284(33):22029-22040
pubmed: 19502598
Pol Arch Med Wewn. 2011 Sep;121(9):296-301
pubmed: 21909059
Clin Sci (Lond). 2020 Jun 26;134(12):1333-1356
pubmed: 32542397
Scand Cardiovasc J. 2018 Oct;52(5):244-249
pubmed: 29893146
Clin Oncol (R Coll Radiol). 2008 Apr;20(3):268
pubmed: 18261890
J Am Soc Nephrol. 2001 Jul;12(7):1434-1447
pubmed: 11423572
FASEB J. 2005 May;19(7):716-28
pubmed: 15857886
EMBO J. 2000 Mar 15;19(6):1187-94
pubmed: 10716919
Biomark Med. 2014;8(6):777-89
pubmed: 25224934
Nephrology (Carlton). 2007 Oct;12(5):459-65
pubmed: 17803469
J Am Soc Nephrol. 2001 Jul;12(7):1448-1457
pubmed: 11423573
Hypertension. 2013 Dec;62(6):1146-51
pubmed: 24082055
Proc Natl Acad Sci U S A. 1994 May 10;91(10):4234-8
pubmed: 8183894
J Pathol. 2007 Jan;211(1):95-108
pubmed: 17136757
Fibrogenesis Tissue Repair. 2010 Aug 05;3:13
pubmed: 20687922
Circulation. 1999 Apr 6;99(13):1726-32
pubmed: 10190883
Pflugers Arch. 2016 Jul;468(7):1259-1270
pubmed: 27023352
Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12509-14
pubmed: 11606725
Circ J. 2010 Jan;74(1):45-6
pubmed: 20035088
Cardiology. 2015;130(1):17-22
pubmed: 25428583
Exp Biol Med (Maywood). 2014 May 28;239(8):998-1006
pubmed: 24872431
Cancer Lett. 2014 May 28;347(1):105-13
pubmed: 24530229
Mod Pathol. 2005 May;18(5):663-72
pubmed: 15605080
J Formos Med Assoc. 2006 May;105(5):377-83
pubmed: 16638647
Exp Cell Res. 2006 Mar 10;312(5):594-607
pubmed: 16376330
J Cell Sci. 1999 Mar;112 ( Pt 6):761-72
pubmed: 10036227
Int J Biol Sci. 2012;8(4):430-41
pubmed: 22419888
Circ J. 2010 Jan;74(1):109-19
pubmed: 19966499
J Zhejiang Univ Sci B. 2010 Aug;11(8):599-607
pubmed: 20669350
J Lipid Res. 2005 Sep;46(9):1849-59
pubmed: 15995169
Eur Rev Med Pharmacol Sci. 2019 Mar;23(6):2563-2569
pubmed: 30964184
Chin Med J (Engl). 2019 Nov 20;132(22):2716-2723
pubmed: 31725448
Sci Transl Med. 2012 May 30;4(136):136ra71
pubmed: 22649092
J Vet Med Sci. 2015 Oct;77(10):1289-91
pubmed: 25947888
J Biol Chem. 2004 Jan 23;279(4):2927-36
pubmed: 14585835
J Biol Chem. 2002 Aug 2;277(31):27872-9
pubmed: 12029087
EMBO J. 1998 Mar 16;17(6):1656-64
pubmed: 9501087
Kidney Int. 2019 Feb;95(2):439-446
pubmed: 30591223
Anticancer Res. 2011 Aug;31(8):2651-5
pubmed: 21778318
Cancer Res. 1999 Dec 15;59(24):6052-6
pubmed: 10626789
J Am Coll Cardiol. 2004 Apr 21;43(8):1383-7
pubmed: 15093871

Auteurs

Mei Li (M)

Fifth Department of Medicine (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, University of Heidelberg, Heidelberg, Germany.

Zoran Popovic (Z)

Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg, Heidelberg, Germany.

Chang Chu (C)

Fifth Department of Medicine (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, University of Heidelberg, Heidelberg, Germany.
Department of Nephrology, Charité, Universitätsmedizin Berlin, Berlin, Germany.

Bernhard K Krämer (BK)

Fifth Department of Medicine (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, University of Heidelberg, Heidelberg, Germany.
European Center for Angioscience, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany.
Center for Innate Immunoscience, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany.

Berthold Hocher (B)

Fifth Department of Medicine (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, University of Heidelberg, Heidelberg, Germany.
Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, School of Medicine, Hunan Normal University, Changsha, China.
Institute of Medical Diagnostics, IMD Berlin, Berlin, Germany.

Classifications MeSH