Choroidal neovascularization complicating sclerochoroidal calcifications.
Choroidal neovascularization
FAF
Multimodal imaging
OCT
OCTA
Sclerochoroidal calcification
Journal
American journal of ophthalmology case reports
ISSN: 2451-9936
Titre abrégé: Am J Ophthalmol Case Rep
Pays: United States
ID NLM: 101679941
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
29
03
2021
revised:
25
09
2021
accepted:
18
11
2021
entrez:
13
12
2021
pubmed:
14
12
2021
medline:
14
12
2021
Statut:
epublish
Résumé
Sclerochoroidal calcifications (SCC) are rare conditions characterized by unifocal or multifocal well-defined scleral deposits of calcium. The present study describes two cases of SCC complicated by the onset of choroidal neovascularization (CNV). Five patients affected by SCC were enrolled in the study and two cases were complicated by CNV. Both patients underwent complete ophthalmic examination with multimodal imaging including optical coherence tomography angiography (OCTA). In the two patients with CNV (1 male), BCVA was 20/40 and 20/50 in the affected eyes. Fundus examination revealed an irregular yellow-white lesion close to the superotemporal arcade in both patients, with exudation. The diagnosis of CNV was performed by means of fluorescein angiography in one patient and OCTA in the other patient. The patients received a total of 3 and 9 ranibizumab injections respectively over a six-year follow-up, reaching a final BCVA of 20/25 in both patients with stabilization of the CNV. SCC may be complicated by CNV, with good management obtained by intravitreal anti-VEGF injections.
Identifiants
pubmed: 34901522
doi: 10.1016/j.ajoc.2021.101235
pii: S2451-9936(21)00244-9
pmc: PMC8640104
doi:
Types de publication
Case Reports
Langues
eng
Pagination
101235Informations de copyright
© 2021 The Authors. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
All the authors have no conflict of interest.
Références
Klin Monbl Augenheilkd. 2008 May;225(5):473-5
pubmed: 18454402
JAMA Ophthalmol. 2019 Jan 1;137(1):111-112
pubmed: 30326002
Arch Ophthalmol. 2000 Jun;118(6):854-7
pubmed: 10865331
Middle East Afr J Ophthalmol. 2014 Jul-Sep;21(3):244-50
pubmed: 25100910
Am J Ophthalmol. 1998 Aug;126(2):320-2
pubmed: 9727535
BMC Ophthalmol. 2020 Jun 22;20(1):248
pubmed: 32571266
Ophthalmology. 1991 May;98(5):720-4
pubmed: 2062507
Arch Ophthalmol. 2001 Jun;119(6):833-40
pubmed: 11405834
Retina. 2002 Jun;22(3):251-61
pubmed: 12055456
Retina. 2015 Mar;35(3):547-54
pubmed: 25574788
Can J Ophthalmol. 2021 Jun;56(3):e98-e101
pubmed: 33249112
J Ophthalmol. 2014;2014:210458
pubmed: 25147732
Retina. 2015 Jul;35(7):1407-14
pubmed: 25658177
Ocul Oncol Pathol. 2016 Oct;2(4):234-238
pubmed: 27843902
Retin Cases Brief Rep. 2007 Summer;1(3):141-4
pubmed: 25390777