The psychopathological impact of the SARS-CoV-2 epidemic on subjects suffering from different mental disorders: An observational retrospective study.
COVID-19
Obsessive-compulsive symptoms
Outpatients
Pandemic
Personality disorders
Psychotic symptoms
Journal
Psychiatry research
ISSN: 1872-7123
Titre abrégé: Psychiatry Res
Pays: Ireland
ID NLM: 7911385
Informations de publication
Date de publication:
01 2022
01 2022
Historique:
received:
29
04
2021
revised:
22
11
2021
accepted:
05
12
2021
pubmed:
14
12
2021
medline:
11
1
2022
entrez:
13
12
2021
Statut:
ppublish
Résumé
SARS-CoV-2 infection causes a pulmonary disease (COVID-19) which spread worldwide generating fear, anxiety, depression in the general population as well as among subjects affected by mental disorders. Little is known about which different psychopathological changes the pandemic caused among individuals affected by different psychiatric disorders, which represents the aim of the present study. Specific psychometric scales were administered at three time points: T0 as outbreak of pandemic, T1 as lockdown period, T2 as reopening. Descriptive analyses and linear regression models were performed. A total of 166 outpatients were included. Overall, psychometric scores showed a significant worsening at T1 with a mild improvement at T2. Only psychopathology in schizophrenia (SKZ) patients and obsessive-compulsive (OC) symptoms did not significantly improve at T2. Subjects affected by personality disorders (PDs) resulted to be more compromised in terms of general psychopathology than depressed and anxiety/OC ones, and showed more severe anxiety symptoms than SKZ patients. In conclusion, subjects affected by PDs require specific clinical attention during COVID-19 pandemic. Moreover, the worsening of SKZ and OC symptoms should be strictly monitored by clinicians, as these aspects did not improve with the end of lockdown measures. Further studies on larger samples are needed to confirm our results. ClinicalTrials.gov Identifier: NCT04694482.
Identifiants
pubmed: 34902818
pii: S0165-1781(21)00629-6
doi: 10.1016/j.psychres.2021.114334
pmc: PMC8664498
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT04694482']
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
114334Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.
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