Evaluation of Inflammasome Activation in Peripheral Blood Mononuclear Cells of Hemodialysis Treated Patients with Glomerulonephritis.

Glomerulonephritis Hemodialysis Inflammasomes NLRC4 NLRP3

Journal

Iranian journal of pharmaceutical research : IJPR
ISSN: 1735-0328
Titre abrégé: Iran J Pharm Res
Pays: Netherlands
ID NLM: 101208407

Informations de publication

Date de publication:
2021
Historique:
entrez: 14 12 2021
pubmed: 15 12 2021
medline: 15 12 2021
Statut: ppublish

Résumé

Recently, it has been found that abnormal activation of inflammasomes, the intracellular multiprotein complexes, plays an important role in the pathogenesis and the development of inflammatory diseases. To determine whether the NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is involved in chronic inflammatory condition reported in glomerulonephritic- hemodialysis (HD) patients, we investigated the mRNA levels of

Identifiants

pubmed: 34904012
doi: 10.22037/ijpr.2020.114260.14757
pmc: PMC8653650
doi:

Types de publication

Journal Article

Langues

eng

Pagination

609-617

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Auteurs

Atieh Hashemi (A)

Department of Pharmaceutical Biotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Razieh Bigdeli (R)

Research and Development Laboratory, Javid Biotechnology Institute, Tehran, Iran.

Masoumeh Shahnazari (M)

Research and Development Laboratory, Javid Biotechnology Institute, Tehran, Iran.

Farshid Oruji (F)

Department of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.

Somayeh Fattahi (S)

Department of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.

Erfan Panahnejad (E)

Research and Development Laboratory, Javid Biotechnology Institute, Tehran, Iran.

Ayda Ghadri (A)

Department of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.

Elmira Movahedi-Asl (E)

Department of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.

Masoumeh Mahdavi-Ourtakand (M)

Department of Biology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.

Vahid Asgary (V)

Research and Development Laboratory, Javid Biotechnology Institute, Tehran, Iran.

Fahimeh Baghbani-Arani (F)

Department of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.

Classifications MeSH