Clinicopathological features of small T1 colorectal cancers.
Biological phenomena
Colorectal cancers
Colorectal neoplasms
Lymphatic metastasis
Polyps
Journal
World journal of clinical cases
ISSN: 2307-8960
Titre abrégé: World J Clin Cases
Pays: United States
ID NLM: 101618806
Informations de publication
Date de publication:
26 Nov 2021
26 Nov 2021
Historique:
received:
27
04
2021
revised:
14
06
2021
accepted:
11
10
2021
entrez:
14
12
2021
pubmed:
15
12
2021
medline:
15
12
2021
Statut:
ppublish
Résumé
Although small colorectal neoplasms (< 10 mm) are often easily resected endoscopically and are considered to have less malignant potential compared with large neoplasms (≥ 10 mm), some are invasive to the submucosa. To clarify the clinicopathological features of small T1 colorectal cancers. Of 32025 colorectal lesions between April 2001 and March 2018, a total of 1152 T1 colorectal cancers resected endoscopically or surgically were included in this study and were divided into two groups by tumor size: a small group (< 10 mm) and a large group (≥ 10 mm). We compared clinicopathological factors including lymph node metastasis (LNM) between the two groups. The incidence of small T1 cancers was 10.1% (116/1152). The percentage of initial endoscopic treatment in small group was significantly higher than in large group (< 10 mm 74.1% Because there was no significant difference in the rate of LNM between small and large T1 colorectal cancers, the requirement for additional surgical resection should be determined according to pathological findings, regardless of tumor size.
Sections du résumé
BACKGROUND
BACKGROUND
Although small colorectal neoplasms (< 10 mm) are often easily resected endoscopically and are considered to have less malignant potential compared with large neoplasms (≥ 10 mm), some are invasive to the submucosa.
AIM
OBJECTIVE
To clarify the clinicopathological features of small T1 colorectal cancers.
METHODS
METHODS
Of 32025 colorectal lesions between April 2001 and March 2018, a total of 1152 T1 colorectal cancers resected endoscopically or surgically were included in this study and were divided into two groups by tumor size: a small group (< 10 mm) and a large group (≥ 10 mm). We compared clinicopathological factors including lymph node metastasis (LNM) between the two groups.
RESULTS
RESULTS
The incidence of small T1 cancers was 10.1% (116/1152). The percentage of initial endoscopic treatment in small group was significantly higher than in large group (< 10 mm 74.1%
CONCLUSION
CONCLUSIONS
Because there was no significant difference in the rate of LNM between small and large T1 colorectal cancers, the requirement for additional surgical resection should be determined according to pathological findings, regardless of tumor size.
Identifiants
pubmed: 34904078
doi: 10.12998/wjcc.v9.i33.10088
pmc: PMC8638043
doi:
Types de publication
Journal Article
Langues
eng
Pagination
10088-10097Informations de copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: All authors declare no conflict of interest.
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