In situ lymphoma imaging in a spontaneous mouse model using the Cerenkov Luminescence of F-18 and Ga-67 isotopes.

Animals Fluorodeoxyglucose F18 / pharmacology Gallium Radioisotopes / pharmacology Luminescent Measurements Lymphoma / diagnostic imaging Mice Mice, Inbred BALB C Neoplasms, Experimental / diagnostic imaging Positron-Emission Tomography

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
14 12 2021
Historique:
received: 01 03 2021
accepted: 12 10 2021
entrez: 15 12 2021
pubmed: 16 12 2021
medline: 28 1 2022
Statut: epublish

Résumé

Cerenkov luminescence imaging (CLI) is a promising approach to image-guided surgery and pathological sampling. It could offer additional advantages when combined to whole-body isotope tomographies. We aimed to obtain evidence of its applicability in lymphoma patho-diagnostics, thus we decided to investigate the radiodiagnostic potential of combined PET or SPECT/CLI in an experimental, novel spontaneous high-grade B-cell lymphoma mouse model (Bc.DLFL1). We monitored the lymphoma dissemination at early stage, and at clinically relevant stages such as advanced stage and terminal stage with in vivo 2-deoxy-2-[

Identifiants

DOI: 10.1038/s41598-021-03505-3 PMID: 34907289 PMC: PMC8671545
pubmed: 34907289
doi: 10.1038/s41598-021-03505-3
pii: 10.1038/s41598-021-03505-3
pmc: PMC8671545
doi:

Substances chimiques

Gallium Radioisotopes 0
Fluorodeoxyglucose F18 0Z5B2CJX4D
Gallium-67 4LJK511Z86

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

24002

Informations de copyright

© 2021. The Author(s).

Références

Eur J Nucl Med Mol Imaging. 2013 Jan;40(1):133-40
pubmed: 23064544
J Nucl Med. 2017 Jan;58(1):175-180
pubmed: 27539844
Semin Nucl Med. 2018 Jul;48(4):359-366
pubmed: 29852945
Eur J Haematol. 1993 Oct;51(4):206-8
pubmed: 8243608
EJNMMI Radiopharm Chem. 2019 Oct 11;4(1):27
pubmed: 31659527
Cancer. 2019 Sep 15;125(18):3111-3120
pubmed: 31287161
Blood Rev. 2016 Nov;30(6):477-491
pubmed: 27596109
J Biophotonics. 2018 Oct;11(10):e201800093
pubmed: 29770603
Eur J Nucl Med Mol Imaging. 2010 Jan;37(1):181-200
pubmed: 19915839
PET Clin. 2019 Jul;14(3):317-329
pubmed: 31084772
Nanomedicine. 2019 Apr;17:62-70
pubmed: 30654183
Eur J Nucl Med Mol Imaging. 2011 Dec;38(12):2136-44
pubmed: 21858528
J Immunol. 2020 Jan 1;204(1):23-36
pubmed: 31767783
Semin Nucl Med. 2018 Jan;48(1):76-81
pubmed: 29195620
Philos Trans A Math Phys Eng Sci. 2011 Nov 28;369(1955):4605-19
pubmed: 22006909
Nature. 2000 Feb 3;403(6769):503-11
pubmed: 10676951
J Nucl Med. 2017 Jun;58(6):891-898
pubmed: 27932562
Cancer Metastasis Rev. 2012 Jun;31(1-2):89-97
pubmed: 22134656
N Engl J Med. 2018 Apr 12;378(15):1396-1407
pubmed: 29641966
Semin Nucl Med. 2018 Jan;48(1):4-16
pubmed: 29195617
Clin Transl Imaging. 2016;4(5):353-366
pubmed: 27738626
Haematologica. 2016 Oct;101(10):1244-1250
pubmed: 27354024
Mol Imaging. 2011 Jun;10(3):177-86, 1-3
pubmed: 21496448
Eur J Nucl Med Mol Imaging. 2003 Jun;30 Suppl 1:S65-81
pubmed: 12644887
J Clin Oncol. 2014 Sep 20;32(27):3059-68
pubmed: 25113753
Int J Hematol. 2018 Feb;107(2):194-200
pubmed: 28994017
Phys Med. 2015 Mar;31(2):120-9
pubmed: 25555905
Eur J Nucl Med Mol Imaging. 2020 Oct;47(11):2624-2632
pubmed: 32242253
J Clin Oncol. 2014 Sep 20;32(27):3048-58
pubmed: 25113771
Theranostics. 2018 Jul 01;8(14):3991-4002
pubmed: 30083276
Br J Cancer. 1995 Dec;72(6):1541-6
pubmed: 8519674
Br J Haematol. 2016 Jul;174(1):43-56
pubmed: 27196701
Blood. 2016 May 19;127(20):2375-90
pubmed: 26980727
Nucl Med Biol. 2014 Jul;41(6):441-9
pubmed: 24776093
J Nucl Med. 2000 Dec;41(12):2089-97
pubmed: 11138697
Pathol Oncol Res. 2016 Apr;22(2):421-30
pubmed: 26584567
Blood. 2011 May 12;117(19):5019-32
pubmed: 21300984
Nucl Med Biol. 2017 Mar;46:12-18
pubmed: 27915165
Nucl Med Biol. 2020 Jan - Feb;80-81:57-64
pubmed: 31889612
Eur J Nucl Med Mol Imaging. 2017 Mar;44(3):517-532
pubmed: 27844106
PLoS One. 2012;7(2):e31402
pubmed: 22363636
Eur J Nucl Med Mol Imaging. 2013 Aug;40(8):1283-91
pubmed: 23674205
Semin Nucl Med. 2018 Jan;48(1):50-66
pubmed: 29195618
J Clin Oncol. 2007 Feb 10;25(5):571-8
pubmed: 17242397
PET Clin. 2016 Jan;11(1):57-64
pubmed: 26590444
Ann Oncol. 2011 Feb;22(2):405-10
pubmed: 20675560
J Biomed Opt. 2016 May 1;21(5):50502
pubmed: 27156713
Crit Rev Oncol Hematol. 2013 Aug;87(2):146-71
pubmed: 23375551
Pathology. 2018 Jan;50(1):74-87
pubmed: 29167021

Auteurs

Zsombor Ritter (Z)

Department of Nuclear Medicine, Medical School, University of Pécs, Pécs, Hungary.

Katalin Zámbó (K)

Department of Nuclear Medicine, Medical School, University of Pécs, Pécs, Hungary.

Péter Balogh (P)

Department of Immunology and Biotechnology, University of Pécs, Pécs, Hungary.

Dávid Szöllősi (D)

Department of Biophysics and Radiation Biology, Semmelweis University Faculty of Medicine, Budapest, Hungary.

Xinkai Jia (X)

Department of Immunology and Biotechnology, University of Pécs, Pécs, Hungary.

Ákos Balázs (Á)

Semmelweis University Faculty of Medicine 1st Department of Surgery, Budapest, Hungary.

Gabriella Taba (G)

Semmelweis University Dosimetry and Medical Physics Service, Budapest, Hungary.

Dániel Dezső (D)

Department of Nuclear Medicine, Medical School, University of Pécs, Pécs, Hungary.

Ildikó Horváth (I)

Department of Biophysics and Radiation Biology, Semmelweis University Faculty of Medicine, Budapest, Hungary.

Hussain Alizadeh (H)

1St Department of Internal Medicine, University of Pécs Medical School, Pécs, Hungary.

David Tuch (D)

Lightpoint Medical Ltd., Rickmansworth, UK.

Kunal Vyas (K)

Lightpoint Medical Ltd., Rickmansworth, UK.

Nikolett Hegedűs (N)

Department of Biophysics and Radiation Biology, Semmelweis University Faculty of Medicine, Budapest, Hungary.
CROmed Ltd., Budapest, Hungary.

Tibor Kovács (T)

Institute of Radiochemistry and Radioecology, University of Pannonia, Veszprém, Hungary.

Krisztián Szigeti (K)

Department of Biophysics and Radiation Biology, Semmelweis University Faculty of Medicine, Budapest, Hungary.

Domokos Máthé (D)

Department of Biophysics and Radiation Biology, Semmelweis University Faculty of Medicine, Budapest, Hungary. domokos.mathe@cromedresearch.com.
CROmed Ltd., Budapest, Hungary. domokos.mathe@cromedresearch.com.
In vivo Imaging Advanced Core Facility, Hungarian Center of Excellence for Molecular Medicine (HCEMM), Budapest, Hungary. domokos.mathe@cromedresearch.com.

Erzsébet Schmidt (E)

Department of Nuclear Medicine, Medical School, University of Pécs, Pécs, Hungary.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › In situ lymphoma imaging in a spontaneous...
questionsmedicales.fr › Glucides › Désoses › Désoxyglucose › Fluorodésoxyglucose F18 › In situ lymphoma imaging in a spontaneous...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Gallium › Isotopes du gallium › Radio-isotopes du gallium › In situ lymphoma imaging in a spontaneous...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Photométrie › Mesures de luminescence › In situ lymphoma imaging in a spontaneous...
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Syndromes lymphoprolifératifs › Lymphomes › In situ lymphoma imaging in a spontaneous...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › In situ lymphoma imaging in a spontaneous...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée BALB C › In situ lymphoma imaging in a spontaneous...
questionsmedicales.fr › Techniques d'investigation › Modèles animaux › Tumeurs expérimentales › In situ lymphoma imaging in a spontaneous...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › In situ lymphoma imaging in a spontaneous...