Increased serum myonectin and irisin levels with myonectin and FNDC5 expressions in polycystic ovary syndrome: a case control study.
Polycystic ovary syndrome
insulin resistance
irisin
myonectin
Journal
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
ISSN: 1364-6893
Titre abrégé: J Obstet Gynaecol
Pays: England
ID NLM: 8309140
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
pubmed:
16
12
2021
medline:
20
8
2022
entrez:
15
12
2021
Statut:
ppublish
Résumé
The aim of this study is to assess the FNDC5 and myonectin expressions and serum levels of myonectin and irisin in women with PCOS. 90 participants were included in this case-control study. 45 of these participants were with PCOS, and 45 of them were healthy volunteers matched for age and body mass index (BMI). Serum irisin and myonectin levels were measured with commercially available enzyme-linked immune sorbent assay (ELISA) kits. Expression of the myonectin and FNDC5 genes were determined by RT-PCR analysis. It was found out that FSI, HOMA-IR, LH, LH/FSH, TT, serum irisin and serum myonectin levels, myonectin mRNA expression, and FNDC5 mRNA expression were higher in the PCOS group, whereas HDL-C level was lower in the PCOS group (
Identifiants
pubmed: 34907845
doi: 10.1080/01443615.2021.1980516
doi:
Substances chimiques
Biomarkers
0
C1QTNF5 protein, human
0
FNDC5 protein, human
0
Fibronectins
0
RNA, Messenger
0
Collagen
9007-34-5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM