Biallelic mutations in


Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
15 12 2021
Historique:
received: 27 07 2021
accepted: 04 12 2021
entrez: 15 12 2021
pubmed: 16 12 2021
medline: 27 1 2022
Statut: epublish

Résumé

CRAC channel regulator 2 A (CRACR2A) is a large Rab GTPase that is expressed abundantly in T cells and acts as a signal transmitter between T cell receptor stimulation and activation of the Ca

Identifiants

pubmed: 34908525
doi: 10.7554/eLife.72559
pii: 72559
pmc: PMC8673834
doi:
pii:

Substances chimiques

Calcium Release Activated Calcium Channels 0
Cytokines 0
Receptors, Antigen, T-Cell 0

Types de publication

Case Reports Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIH HHS
ID : AI147063
Pays : United States
Organisme : NIH HHS
ID : AI146615
Pays : United States
Organisme : NIH HHS
ID : AI149236
Pays : United States
Organisme : NIAID NIH HHS
ID : P30 AI028697
Pays : United States
Organisme : Medical Research Council
ID : MR/T004134/1
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : P30 CA016042
Pays : United States
Organisme : NIH HHS
ID : AI083432
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI146615
Pays : United States

Informations de copyright

© 2021, Wu et al.

Déclaration de conflit d'intérêts

BW, LR, JS, DL, KW, CC, LM, RA, GD, SS, YG No competing interests declared, SS Received research grant funding and payments from CSL Behring for advisory board participation

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Auteurs

Beibei Wu (B)

Department of Physiology, David Geffen School of Medicine, UCLA, Los Angeles, United States.

Laura Rice (L)

Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom.

Jennifer Shrimpton (J)

Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom.

Dylan Lawless (D)

Global Health Institute, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Kieran Walker (K)

Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom.

Clive Carter (C)

Department of Clinical Immunology and Allergy, St James's University Hospital, Leeds, United Kingdom.

Lynn McKeown (L)

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.

Rashida Anwar (R)

Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom.

Gina M Doody (GM)

Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom.

Sonal Srikanth (S)

Department of Physiology, David Geffen School of Medicine, UCLA, Los Angeles, United States.

Yousang Gwack (Y)

Department of Physiology, David Geffen School of Medicine, UCLA, Los Angeles, United States.

Sinisa Savic (S)

Department of Clinical Immunology and Allergy, St James's University Hospital, Leeds, United Kingdom.
National Institute for Health Research-Leeds Biomedical Research Centre and Leeds Institute of Rheumatic and Musculoskeletal Medicine, Wellcome Trust Brenner Building, St James's University Hospital, Leeds, United Kingdom.

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Classifications MeSH