Neurosyphilis Mimicking Autoimmune Encephalitis: A Case Report and Review of the Literature.
autoimmune encephalitis
epilepsy
neurosyphilis
Journal
Clinical neuropsychiatry
ISSN: 2385-0787
Titre abrégé: Clin Neuropsychiatry
Pays: Italy
ID NLM: 101237961
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
entrez:
15
12
2021
pubmed:
1
6
2020
medline:
1
6
2020
Statut:
ppublish
Résumé
Neurosyphilis may imitate a wide range of neurological and psychiatric diseases, including autoimmune encephalitis. To avoid further cognitive decline and morbidity, early recognition and adequate treatment are of particular importance in both neurosyphilis and autoimmune encephalitis. In case of a strong clinical suspicion of a diagnosis of autoimmune encephalitis, guidelines recommend initiating immunotherapy even in the absence of immunological confirmation. Here, a case of neurosyphilis is reported in which the potential overlap in clinical presentation of autoimmune encephalitis and parenchymatous neurosyphilis is discussed. The here reported data suggest that, in cases presenting with new onset focal epilepsy, slowing of electroencephalographic activity over the temporal regions and magnetic resonance imaging suggestive of swelling of the amygdala, neurosyphilis should be excluded prior to initiation of immunotherapy for suspected autoimmune encephalitis.
Identifiants
pubmed: 34908989
doi: 10.36131/cnfioritieditore20200305
pmc: PMC8650208
doi:
Types de publication
Case Reports
Langues
eng
Pagination
175-180Informations de copyright
© 2020 Giovanni Fioriti Editore s.r.l.
Déclaration de conflit d'intérêts
Competing interests: none.
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