Bipolar Disorder Treatments and Ovarian Cancer: A Systematic Review.
atypical neuroleptics
bipolar disorders
mood stabilizers
ovarian cancer
psychopharmacology
Journal
Clinical neuropsychiatry
ISSN: 2385-0787
Titre abrégé: Clin Neuropsychiatry
Pays: Italy
ID NLM: 101237961
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
entrez:
15
12
2021
pubmed:
1
10
2020
medline:
1
10
2020
Statut:
ppublish
Résumé
We reviewed literature on drugs for bipolar disorders (BD), utilized in ovarian cancer (OC). We adhered to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines in completion of this systematic review. We identified 73 papers. Thirty-two studies were finally included. BD is rarely diagnosed in OC patients. Limited finding from case reports is available. Drugs used to treat BD (mainly lithium and valproic acid) have been extensively studied in add-on to chemotherapy for treatment-resistant OC cells or in animal models, with promising results in vitro but not in vivo. The clinical underestimation of BD in OC has leaded to the almost complete absence of evidences for a soundly based clinical guidance in this field. There is a urgent need for a systematic multi-disciplinary approach to OC.
Identifiants
pubmed: 34909008
doi: 10.36131/cnfioritieditore20200508
pmc: PMC8629050
doi:
Types de publication
Journal Article
Langues
eng
Pagination
300-313Informations de copyright
© 2020 Giovanni Fioriti Editore s.r.l.
Déclaration de conflit d'intérêts
Competing interests: None.
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