Revisiting the role of pulmonary surfactant in chronic inflammatory lung diseases and environmental exposure.
Journal
European respiratory review : an official journal of the European Respiratory Society
ISSN: 1600-0617
Titre abrégé: Eur Respir Rev
Pays: England
ID NLM: 9111391
Informations de publication
Date de publication:
31 Dec 2021
31 Dec 2021
Historique:
received:
17
03
2021
accepted:
05
08
2021
entrez:
16
12
2021
pubmed:
17
12
2021
medline:
18
12
2021
Statut:
epublish
Résumé
Pulmonary surfactant is a crucial and dynamic lung structure whose primary functions are to reduce alveolar surface tension and facilitate breathing. Though disruptions in surfactant homeostasis are typically thought of in the context of respiratory distress and premature infants, many lung diseases have been noted to have significant surfactant abnormalities. Nevertheless, preclinical and clinical studies of pulmonary disease too often overlook the potential contribution of surfactant alterations - whether in quantity, quality or composition - to disease pathogenesis and symptoms. In inflammatory lung diseases, whether these changes are cause or consequence remains a subject of debate. This review will outline 1) the importance of pulmonary surfactant in the maintenance of respiratory health, 2) the diseases associated with primary surfactant dysregulation, 3) the surfactant abnormalities observed in inflammatory pulmonary diseases and, finally, 4) the available research on the interplay between surfactant homeostasis and smoking-associated lung disease. From these published studies, we posit that changes in surfactant integrity and composition contribute more considerably to chronic inflammatory pulmonary diseases and that more work is required to determine the mechanisms underlying these alterations and their potential treatability.
Identifiants
pubmed: 34911693
pii: 30/162/210077
doi: 10.1183/16000617.0077-2021
pmc: PMC9489000
pii:
doi:
Substances chimiques
Pulmonary Surfactants
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright ©The authors 2021.
Déclaration de conflit d'intérêts
Provenance: Submitted article, peer reviewed. Conflict of interest: N. Milad has nothing to disclose. Conflict of interest: M.C. Morissette has nothing to disclose.
Références
Commun Biol. 2019 Dec 16;2:470
pubmed: 31872075
BMC Pulm Med. 2008 Apr 11;8:6
pubmed: 18405368
Breathe (Sheff). 2020 Jun;16(2):200018
pubmed: 32684997
Eur Respir J. 1994 Nov;7(11):1944-9
pubmed: 7875263
Am J Physiol Lung Cell Mol Physiol. 2002 Oct;283(4):L755-65
pubmed: 12225952
Arerugi. 1991 Feb;40(2):160-3
pubmed: 2069516
Am J Respir Crit Care Med. 1997 Apr;155(4):1254-9
pubmed: 9105063
PLoS One. 2020 Feb 6;15(2):e0228279
pubmed: 32027677
Lancet Respir Med. 2019 Dec;7(12):1017-1026
pubmed: 31711871
Pediatr Res. 2006 Jun;59(6):801-5
pubmed: 16641205
Chest. 1996 Apr;109(4):1006-9
pubmed: 8635323
Am J Physiol Lung Cell Mol Physiol. 2001 Sep;281(3):L697-703
pubmed: 11504698
J Immunol. 2001 Nov 15;167(10):5868-73
pubmed: 11698462
Lancet. 2017 May 13;389(10082):1931-1940
pubmed: 28513453
J Appl Toxicol. 2019 Apr;39(4):658-671
pubmed: 30565269
Eur Respir J. 1999 Jun;13(6):1455-76
pubmed: 10445627
Pediatrics. 2017 Aug;140(2):
pubmed: 28771412
Clin Exp Allergy. 1997 Mar;27(3):337-42
pubmed: 9088661
N Engl J Med. 2019 Sep 5;381(10):923-932
pubmed: 31483963
Infect Immun. 2001 Feb;69(2):758-64
pubmed: 11159965
Chest. 2010 Jan;137(1):37-45
pubmed: 19741063
Am J Physiol Lung Cell Mol Physiol. 2000 Feb;278(2):L305-11
pubmed: 10666114
Am Rev Respir Dis. 1978 Nov;118(5):863-75
pubmed: 736357
Chest. 2009 Aug;136(2):571-577
pubmed: 19666756
Am Rev Respir Dis. 1990 Apr;141(4 Pt 1):1006-13
pubmed: 1691603
Am J Respir Cell Mol Biol. 2002 Mar;26(3):257-60
pubmed: 11867330
J Immunol. 2021 Apr 15;206(8):1923-1931
pubmed: 33722877
Science. 1994 Apr 29;264(5159):713-6
pubmed: 8171324
Biol Neonate. 1995;68(4):229-45
pubmed: 8580214
J Immunol. 2002 Oct 1;169(7):3978-86
pubmed: 12244199
J Histochem Cytochem. 1983 Nov;31(11):1298-304
pubmed: 6688627
Biochim Biophys Acta. 2013 Feb;1831(2):448-58
pubmed: 23200861
J Biol Chem. 1997 Apr 11;272(15):9640-7
pubmed: 9092492
Am J Respir Cell Mol Biol. 1998 Oct;19(4):700-8
pubmed: 9761768
Am J Respir Crit Care Med. 1999 Apr;159(4 Pt 1):1115-8
pubmed: 10194154
Biochim Biophys Acta. 2008 Jul-Aug;1778(7-8):1676-95
pubmed: 18515069
Chest. 1989 Jan;95(1):82-9
pubmed: 2909359
Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1260-71
pubmed: 27106287
J Pediatr. 1983 Mar;102(3):443-7
pubmed: 6687477
Am J Respir Crit Care Med. 2010 May 15;181(10):1098-105
pubmed: 20133924
Lancet. 1999 Apr 10;353(9160):1232-7
pubmed: 10217084
Respir Res. 2018 Aug 31;19(1):163
pubmed: 30165864
Infect Immun. 2002 Nov;70(11):6129-39
pubmed: 12379690
Am J Respir Crit Care Med. 1999 Jun;159(6):1803-9
pubmed: 10351922
Am Rev Respir Dis. 1988 Sep;138(3):709-13
pubmed: 2462382
Nat Rev Dis Primers. 2019 Mar 7;5(1):16
pubmed: 30846703
Lung. 2012 Apr;190(2):169-82
pubmed: 21986851
Eur Respir J. 1990 Nov;3(10):1128-39
pubmed: 2090475
Am J Physiol Lung Cell Mol Physiol. 2002 Mar;282(3):L563-72
pubmed: 11839553
Microbes Infect. 2001 Feb;3(2):161-6
pubmed: 11251302
Eur Respir J. 2015 Nov;46(5):1451-60
pubmed: 26113683
Microbes Infect. 2012 Jan;14(1):17-25
pubmed: 21945366
N Engl J Med. 1972 Feb 3;286(5):223-7
pubmed: 5066599
J Perinatol. 2000 Oct-Nov;20(7):414-20
pubmed: 11076324
Anat Rec. 1969 Apr;163(4):497-507
pubmed: 5776878
J Clin Invest. 1982 Sep;70(3):673-83
pubmed: 6896715
Am J Respir Crit Care Med. 1996 Oct;154(4 Pt 1):1002-5
pubmed: 8887598
Am J Respir Cell Mol Biol. 2015 Jul;53(1):74-86
pubmed: 25409201
Am J Respir Crit Care Med. 1998 Feb;157(2):658-64
pubmed: 9476887
Eur Respir J. 1993 Jul;6(7):971-7
pubmed: 8370446
Pediatr Pulmonol. 2020 Jan;55(1):226-228
pubmed: 31746559
Arch Dis Child Fetal Neonatal Ed. 1997 Sep;77(2):F147-50
pubmed: 9377142
Ann Med. 1993 Jun;25(3):285-8
pubmed: 8333929
Chem Res Toxicol. 2020 Sep 21;33(9):2432-2440
pubmed: 32842741
Am J Respir Crit Care Med. 1995 Dec;152(6 Pt 1):1860-6
pubmed: 8520747
J Huazhong Univ Sci Technolog Med Sci. 2008 Apr;28(2):128-31
pubmed: 18480979
Respir Res. 2011 Mar 11;12:29
pubmed: 21396106
Biomed Res Int. 2015;2015:639543
pubmed: 26495308
Am J Respir Cell Mol Biol. 1999 Feb;20(2):279-86
pubmed: 9922219
N Engl J Med. 2019 Oct 31;381(18):1780-1781
pubmed: 31577870
Thorax. 1992 Aug;47(8):603-8
pubmed: 1412116
JAMA. 1997 Nov 5;278(17):1426-31
pubmed: 9356001
Am J Respir Crit Care Med. 1995 Sep;152(3):1050-4
pubmed: 7663782
J Appl Physiol (1985). 1987 Feb;62(2):429-37
pubmed: 3558203
Am Rev Respir Dis. 1988 Mar;137(3):585-91
pubmed: 3345040
Eur J Pediatr. 1992 Aug;151(8):596-600
pubmed: 1505580
Ann Thorac Surg. 1966 May;2(3):327-33
pubmed: 5954467
J Infect Dis. 2001 Mar 15;183(6):943-52
pubmed: 11237812
Front Immunol. 2019 Mar 18;10:458
pubmed: 30936871
J Immunol. 2008 Mar 1;180(5):3305-12
pubmed: 18292555
J Appl Physiol (1985). 1985 Jun;58(6):1866-73
pubmed: 2989240
Thorax. 1993 Aug;48(8):840-4
pubmed: 8211875
Am Rev Respir Dis. 1991 Jul;144(1):160-6
pubmed: 2064123
Nat Commun. 2013;4:2563
pubmed: 24113622
Am J Respir Crit Care Med. 1999 Jul;160(1):336-41
pubmed: 10390421
Lancet. 2019 Dec 7;394(10214):2073-2083
pubmed: 31711629
Biochim Biophys Acta. 1995 Dec 7;1259(3):235-44
pubmed: 8541330
Biochim Biophys Acta. 2009 Feb;1788(2):358-70
pubmed: 19118518
Respir Res. 2017 Nov 17;18(1):193
pubmed: 29149889
Open Respir Med J. 2012;6:44-53
pubmed: 22859930
Am J Respir Crit Care Med. 2008 Jul 15;178(2):158-67
pubmed: 18420961
Cell. 2003 Oct 3;115(1):13-23
pubmed: 14531999
Sci Rep. 2021 Feb 18;11(1):4106
pubmed: 33602992
Am J Physiol. 1997 Oct;273(4):L709-14
pubmed: 9357844
Am J Respir Crit Care Med. 1997 Aug;156(2 Pt 1):445-53
pubmed: 9279222
Viral Immunol. 2002;15(2):357-63
pubmed: 12081017
Eur Respir J. 2011 Aug;38(2):277-84
pubmed: 21273386
Clin Chim Acta. 1989 Apr 28;181(1):11-8
pubmed: 2721003
Clin Drug Investig. 2014 Aug;34(8):553-64
pubmed: 24890235
Am J Physiol. 1996 Apr;270(4 Pt 1):L650-8
pubmed: 8928826
Am J Respir Crit Care Med. 2000 Oct;162(4 Pt 1):1251-6
pubmed: 11029326
Clin Exp Allergy. 1997 Jul;27(7):802-7
pubmed: 9249273
Lung. 1993;171(5):277-91
pubmed: 8412308
Respir Res. 2017 Feb 28;18(1):41
pubmed: 28241820
Ann Am Thorac Soc. 2015 May;12(5):765-74
pubmed: 25742123
J Immunol. 1997 May 1;158(9):4336-40
pubmed: 9126996
Fundam Appl Toxicol. 1995 Aug;27(1):63-9
pubmed: 7589929
J Appl Physiol (1985). 2000 Oct;89(4):1283-92
pubmed: 11007560
Cell Tissue Res. 2017 Mar;367(3):721-735
pubmed: 27783217
Lancet Respir Med. 2017 Sep;5(9):691-706
pubmed: 28822787
Am J Physiol Lung Cell Mol Physiol. 2019 Apr 1;316(4):L669-L678
pubmed: 30702343
Biochim Biophys Acta. 2010 Jun;1798(6):1281-4
pubmed: 20227386
Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7794-8
pubmed: 7644495
Pediatr Res. 1986 Dec;20(12):1228-35
pubmed: 3797115
Eur Respir J. 2017 Sep 9;50(3):
pubmed: 28889112
Phys Chem Chem Phys. 2018 Oct 3;20(38):24968-24978
pubmed: 30239547
Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L259-71
pubmed: 17496061
Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L313-L327
pubmed: 28450283
Biochim Biophys Acta. 1996 May 31;1301(1-2):90-6
pubmed: 8652656
Clin Exp Allergy. 1995 Nov;25(11):1053-60
pubmed: 8581837
Sci Rep. 2017 Aug 16;7(1):8304
pubmed: 28814727
Am Rev Respir Dis. 1987 Jul;136(1):113-8
pubmed: 2440355
Inhal Toxicol. 2018 Mar - Apr;30(4-5):159-168
pubmed: 29932004
J Immunol. 2000 Oct 1;165(7):3934-40
pubmed: 11034401
Am J Respir Cell Mol Biol. 2004 Feb;30(2):228-32
pubmed: 12920056
Am J Respir Cell Mol Biol. 2001 Dec;25(6):668-72
pubmed: 11726390
J Immunol. 2001 Feb 15;166(4):2727-33
pubmed: 11160338
PLoS One. 2015 Dec 11;10(12):e0144463
pubmed: 26656890
Clin Chim Acta. 1995 Mar 31;235(2):229-34
pubmed: 7554277
Crit Care Med. 1996 Jun;24(6):1062-7
pubmed: 8681574
PLoS One. 2019 Jan 28;14(1):e0210979
pubmed: 30689633
Toxicol Appl Pharmacol. 1996 Oct;140(2):274-80
pubmed: 8887443
Eur Respir J. 2003 Jun;21(6):1046-9
pubmed: 12797502
Pediatr Pulmonol. 1998 Mar;25(3):196-204
pubmed: 9556012
BMC Pulm Med. 2020 Jun 23;20(1):179
pubmed: 32576172
BMC Pulm Med. 2010 Oct 25;10:53
pubmed: 20973980
Am J Med. 1968 Oct;45(4):502-12
pubmed: 5678094
Clin Exp Allergy. 1996 Mar;26(3):270-5
pubmed: 8729663
Clin Physiol. 1991 Sep;11(5):431-8
pubmed: 1934939
MMWR Morb Mortal Wkly Rep. 2019 Nov 15;68(45):1040-1041
pubmed: 31725707
Am J Physiol Lung Cell Mol Physiol. 2002 Nov;283(5):L1002-10
pubmed: 12376353
Am J Respir Crit Care Med. 2006 Jun 15;173(12):1342-7
pubmed: 16556693
Am J Physiol Lung Cell Mol Physiol. 2002 Feb;282(2):L330-9
pubmed: 11792638
J Clin Invest. 1999 Apr;103(7):1015-21
pubmed: 10194474
Lung. 1988;166(5):293-301
pubmed: 3146676
Am J Respir Cell Mol Biol. 2002 Dec;27(6):714-21
pubmed: 12444031
Annu Rev Physiol. 2004;66:601-23
pubmed: 14977415
Blood. 2009 Mar 12;113(11):2547-56
pubmed: 19282464
Annu Rev Physiol. 2002;64:775-802
pubmed: 11826288
Am J Respir Cell Mol Biol. 2002 Mar;26(3):277-82
pubmed: 11867335
Am J Respir Cell Mol Biol. 2018 Aug;59(2):225-236
pubmed: 29465261
Pediatr Res. 1998 May;43(5):666-73
pubmed: 9585014
J Infect Dis. 2004 Apr 15;189(8):1528-39
pubmed: 15073692
Am J Respir Crit Care Med. 1996 Mar;153(3):1148-52
pubmed: 8630559
Biochim Biophys Acta. 1998 Nov 19;1408(2-3):226-40
pubmed: 9813343
Respiration. 1992;59 Suppl 1:28-32
pubmed: 1579729
Curr Opin Immunol. 2009 Oct;21(5):514-21
pubmed: 19796925
Chest. 2003 Mar;123(3 Suppl):355S
pubmed: 12628972
Pediatr Res. 1997 Aug;42(2):169-73
pubmed: 9262218
Drug Des Devel Ther. 2013;7:139-48
pubmed: 23507973
Eur Respir J. 2004 Sep;24(3):426-35
pubmed: 15358702
J Clin Invest. 2019 Oct 1;129(10):4290-4304
pubmed: 31483291
J Biol Chem. 2004 Jun 25;279(26):27688-98
pubmed: 15078883