Cohort profile: The Swiss Transplant Cohort Study (STCS): A nationwide longitudinal cohort study of all solid organ recipients in Switzerland.
epidemiology
immunology
infectious diseases
oncology
transplant medicine
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
15 12 2021
15 12 2021
Historique:
entrez:
16
12
2021
pubmed:
17
12
2021
medline:
8
3
2022
Statut:
epublish
Résumé
The Swiss Transplant Cohort Study (STCS) is a prospective multicentre cohort study which started to actively enrol study participants in May 2008. It takes advantage of combining data from all transplant programmes in one unique system to perform comprehensive nationwide reporting and to promote translational and clinical post-transplant outcome research in the framework of Swiss transplantation medicine. Over 5500 solid organ transplant recipients have been enrolled in all six Swiss transplant centres by end of 2019, around three-quarter of them for kidney and liver transplants. Ninety-three per cent of all transplanted recipients have consented to study participation, almost all of them (99%) contributed to bio-sampling. The STCS genomic data set includes around 3000 patients. Detailed clinical and laboratory data in high granularity as well as patient-reported outcomes from transplant recipients and activities in Switzerland are available in the last decade. Interdisciplinary contributions in diverse fields of transplantation medicine such as infectious diseases, genomics, oncology, immunology and psychosocial science have resulted in approximately 70 scientific papers getting published in peer-review journals so far. The STCS will deepen its efforts in personalised medicine and digital epidemiology, and will also focus on allocation research and the use of causal inference methods to make complex matters in transplant medicine more understandable and transparent.
Identifiants
pubmed: 34911712
pii: bmjopen-2021-051176
doi: 10.1136/bmjopen-2021-051176
pmc: PMC8679072
doi:
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e051176Investigateurs
Patrizia Amico
(P)
Andres Axel
(A)
John-David Aubert
(JD)
Vanessa Banz
(V)
Beckmann Sonja
(B)
Guido Beldi
(G)
Christoph Berger
(C)
Ekaterine Berishvili
(E)
Annalisa Berzigotti
(A)
Isabelle Binet
(I)
Pierre-Yves Bochud
(PY)
Sanda Branca
(S)
Heiner Bucher
(H)
Thierry Carrel
(T)
Emmanuelle Catana
(E)
Yves Chalandon
(Y)
Sabina De Geest
(S)
Olivier De Rougemont
(O)
Sophie De Seigneux
(S)
Michael Dickenmann
(M)
Joëlle Lynn Dreifuss
(JL)
Michel Duchosal
(M)
Thomas Fehr
(T)
Sylvie Ferrari-Lacraz
(S)
Nicola Franscini
(N)
Christian Garzoni
(C)
Paola Gasche Soccal
(PG)
Christophe Gaudet
(C)
Déla Golshayan
(D)
Nicolas Goossens
(N)
Karine Hadaya
(K)
Jörg Halter
(J)
Dominik Heim
(D)
Christoph Hess
(C)
Sven Hillinger
(S)
Hans Hirsch
(H)
Patricia Hirt
(P)
Günther Hofbauer
(G)
Uyen Huynh-Do
(U)
Franz Immer
(F)
Michael Koller
(M)
Mirjam Laager
(M)
Bettina Laesser
(B)
Roger Lehmann
(R)
Alexander Leichtle
(A)
Christian Lovis
(C)
Oriol Manuel
(O)
Hans-Peter Marti
(HP)
Pierre Yves Martin
(PY)
Michele Martinelli
(M)
Valérie McLin
(V)
Katell Mellac
(K)
Aurélia Merçay
(A)
Karin Mettler
(K)
Nicolas Mueller
(N)
Antonia Müller
(A)
Ulrike Müller-Arndt
(U)
Beat Müllhaupt
(B)
Mirjam Nägeli
(M)
Graziano Oldani
(G)
Manuel Pascual
(M)
Klara Posfay-Barbe
(K)
Juliane Rick
(J)
Anne Rosselet
(A)
Simona Rossi
(S)
Silvia Rothlin
(S)
Frank Ruschitzka
(F)
Thomas Schachtner
(T)
Urs Schanz
(U)
Stefan Schaub
(S)
Aurelia Schnyder
(A)
Macé Schuurmans
(M)
Thierry Sengstag
(T)
Federico Simonetta
(F)
Susanne Stampf
(S)
Jürg Steiger
(J)
Guido Stirniman
(G)
Ueli Stürzinger
(U)
Christian Van Delden
(CV)
Jean-Pierre Venetz
(JP)
Jean Villard
(J)
Julien Vionnet
(J)
Madeleine Wick
(M)
Markus Wilhlem
(M)
Patrick Yerly
(P)
Informations de copyright
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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