A First in Human Trial Implanting Microalgae Shows Safety of Photosynthetic Therapy for the Effective Treatment of Full Thickness Skin Wounds.
clinical trial
human photosynthesis
microalgae
photosynthetic biomaterial
photosynthetic therapy
skin regeneration
skin wounds
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2021
2021
Historique:
received:
07
09
2021
accepted:
11
10
2021
entrez:
17
12
2021
pubmed:
18
12
2021
medline:
18
12
2021
Statut:
epublish
Résumé
Insufficient oxygen supply represents a relevant issue in several fields of human physiology and medicine. It has been suggested that the implantation of photosynthetic cells can provide oxygen to tissues in the absence of a vascular supply. This approach has been demonstrated to be successful in several
Identifiants
pubmed: 34917636
doi: 10.3389/fmed.2021.772324
pmc: PMC8669306
doi:
Banques de données
ClinicalTrials.gov
['NCT03960164']
Types de publication
Journal Article
Langues
eng
Pagination
772324Informations de copyright
Copyright © 2021 Obaíd, Camacho, Brenet, Corrales-Orovio, Carvajal, Martorell, Werner, Simón, Varas, Calderón, Guzmán, Bono, San Martín, Eblen-Zajjur and Egaña.
Déclaration de conflit d'intérêts
JTE is co-founder of SymbiOx Inc., a startup company that owns IP for the technology described here. During the conduct of the trial, MB, RC-O and FC were full-time employees of SymbiOx Inc., while AE-Z, XM and CW were part-time employees. All SymbiOx team members were financed with a R&D grant obtained from the Chilean Ministry of Economics (CORFO 18PIDE98887). The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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