Electronically integrated microcatheters based on self-assembling polymer films.
Journal
Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440
Informations de publication
Date de publication:
17 Dec 2021
17 Dec 2021
Historique:
entrez:
17
12
2021
pubmed:
18
12
2021
medline:
18
12
2021
Statut:
ppublish
Résumé
Existing electronically integrated catheters rely on the manual assembly of separate components to integrate sensing and actuation capabilities. This strongly impedes their miniaturization and further integration. Here, we report an electronically integrated self-assembled microcatheter. Electronic components for sensing and actuation are embedded into the catheter wall through the self-assembly of photolithographically processed polymer thin films. With a diameter of only about 0.1 mm, the catheter integrates actuated digits for manipulation and a magnetic sensor for navigation and is capable of targeted delivery of liquids. Fundamental functionalities are demonstrated and evaluated with artificial model environments and ex vivo tissue. Using the integrated magnetic sensor, we develop a strategy for the magnetic tracking of medical tools that facilitates basic navigation with a high resolution below 0.1 mm. These highly flexible and microsized integrated catheters might expand the boundary of minimally invasive surgery and lead to new biomedical applications.
Identifiants
pubmed: 34919439
doi: 10.1126/sciadv.abl5408
pmc: PMC8682992
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
eabl5408Références
Rev Sci Instrum. 2011 Sep;82(9):094703
pubmed: 21974608
Adv Mater. 2021 Jul;33(26):e2101272
pubmed: 34028906
Small. 2021 Feb;17(5):e2002549
pubmed: 33448115
Adv Mater. 2016 Nov;28(42):9370-9377
pubmed: 27593972
Adv Sci (Weinh). 2021 Sep;8(18):e2101290
pubmed: 34272935
Rev Sci Instrum. 2017 Jul;88(7):073701
pubmed: 28764508
Sci Rep. 2018 Jun 22;8(1):9492
pubmed: 29934604
AJNR Am J Neuroradiol. 2001 Nov-Dec;22(10):1825-32
pubmed: 11733309
Biosens Bioelectron. 2009 Sep 15;25(1):173-8
pubmed: 19625179
Sci Robot. 2021 Aug 18;6(57):
pubmed: 34408094
Adv Mater. 2020 Apr;32(15):e1902994
pubmed: 31512308
Adv Mater. 2019 May;31(22):e1808210
pubmed: 30907471
Sci Robot. 2019 Aug 28;4(33):
pubmed: 33137788
J Vasc Surg. 2018 Apr;67(4):1274-1281
pubmed: 28583735
Sci Adv. 2021 Feb 10;7(7):
pubmed: 33568482
Int J Cardiol. 2013 Nov 5;169(3):157-65
pubmed: 24063921
Proc Inst Mech Eng H. 2010;224(6):743-9
pubmed: 20608491
Nat Biomed Eng. 2020 Oct;4(10):997-1009
pubmed: 32895515
Small. 2020 Sep;16(35):e2002410
pubmed: 32700453
Br J Radiol. 2011 Feb;84(998):184-7
pubmed: 21257838
Nat Commun. 2019 Sep 9;10(1):4087
pubmed: 31501430
Nat Biomed Eng. 2018 Dec;2(12):907-914
pubmed: 31015727
Science. 2019 Mar 1;363(6430):
pubmed: 30819934
Arch Cardiovasc Dis. 2018 Jun - Jul;111(6-7):456-464
pubmed: 29887403
Talanta. 2020 Oct 1;218:121205
pubmed: 32797931
Nat Biomed Eng. 2018 Mar;2(3):165-172
pubmed: 31015715
Small. 2020 Jun;16(24):e2000213
pubmed: 32431083
Nat Commun. 2015 Nov 30;6:10059
pubmed: 26616435
Sci Adv. 2019 Dec 20;5(12):eaay7459
pubmed: 32064322
Nano Lett. 2016 Jul 13;16(7):4288-96
pubmed: 27266478
Sci Adv. 2020 Jan 22;6(4):eaay6094
pubmed: 32010789
Adv Mater. 2015 Nov 18;27(43):6797-805
pubmed: 26397039
Science. 2000 Jun 30;288(5475):2335-8
pubmed: 10875911
IEEE Rev Biomed Eng. 2020;13:212-232
pubmed: 31484133
Neurointervention. 2014 Feb;9(1):39-44
pubmed: 24643022
Neurosurgery. 2001 May;48(5):1100-7; discussion 1107-8
pubmed: 11334277
Nat Commun. 2019 Jul 8;10(1):3013
pubmed: 31285441
Science. 1995 Jun 23;268(5218):1735-8
pubmed: 17834992
Adv Mater. 2016 Jun;28(21):4084-9
pubmed: 27003908
Surg J (N Y). 2017 Nov 09;3(4):e163-e166
pubmed: 29134202
IEEE Trans Biomed Eng. 2017 Aug;64(8):1972-1979
pubmed: 28362578
Nat Commun. 2021 Aug 23;12(1):4967
pubmed: 34426576
Adv Mater. 2015 Nov;27(42):6582-9
pubmed: 26398863
AJNR Am J Neuroradiol. 2017 Jul;38(7):1377-1382
pubmed: 28522669