Outcomes in Pediatric Post-Cardiotomy ECMO Support With Modification of Systematic Support Strategy.


Journal

World journal for pediatric & congenital heart surgery
ISSN: 2150-136X
Titre abrégé: World J Pediatr Congenit Heart Surg
Pays: United States
ID NLM: 101518415

Informations de publication

Date de publication:
Jan 2022
Historique:
entrez: 17 12 2021
pubmed: 18 12 2021
medline: 19 2 2022
Statut: ppublish

Résumé

Utilization of extracorporeal membrane oxygenation (ECMO) support in the post-cardiotomy setting is vital to successful perioperative outcomes following pediatric cardiac surgery. Specific analysis of protocolized management strategies and staff preparedness is imperative to optimizing institutional ECMO outcomes. All patients requiring post-cardiotomy ECMO support at a single institution from 2013 to 2019 were retrospectively reviewed. In 2015, several modifications were made to the ECMO support paradigm that addressed deficiencies in equipment, critical care protocols, and staff preparedness. Cases were stratified according to era of ECMO support; patients supported prior to paradigm change from 2013 to 2015 (Group EARLY, n = 20), and patients supported following the implementation of systematic modifications from 2016 to 2019 (Group LATE, n = 26). The primary outcomes of interest were survival to decannulation and hospital discharge. Median age at cannulation was 24.5 days (IQR 7-96) and median duration of support was 4 days (IQR 2-8). Overall survival to decannulation was 78.3% (65% EARLY vs. 88.5% LATE, Systematic modifications to ECMO support strategy and staff preparation are associated with a significant increase in perioperative survival for pediatric patients requiring post-cardiotomy ECMO support.

Sections du résumé

BACKGROUND BACKGROUND
Utilization of extracorporeal membrane oxygenation (ECMO) support in the post-cardiotomy setting is vital to successful perioperative outcomes following pediatric cardiac surgery. Specific analysis of protocolized management strategies and staff preparedness is imperative to optimizing institutional ECMO outcomes.
METHODS METHODS
All patients requiring post-cardiotomy ECMO support at a single institution from 2013 to 2019 were retrospectively reviewed. In 2015, several modifications were made to the ECMO support paradigm that addressed deficiencies in equipment, critical care protocols, and staff preparedness. Cases were stratified according to era of ECMO support; patients supported prior to paradigm change from 2013 to 2015 (Group EARLY, n = 20), and patients supported following the implementation of systematic modifications from 2016 to 2019 (Group LATE, n = 26). The primary outcomes of interest were survival to decannulation and hospital discharge.
RESULTS RESULTS
Median age at cannulation was 24.5 days (IQR 7-96) and median duration of support was 4 days (IQR 2-8). Overall survival to decannulation was 78.3% (65% EARLY vs. 88.5% LATE,
CONCLUSION CONCLUSIONS
Systematic modifications to ECMO support strategy and staff preparation are associated with a significant increase in perioperative survival for pediatric patients requiring post-cardiotomy ECMO support.

Identifiants

pubmed: 34919487
doi: 10.1177/21501351211060335
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

46-52

Auteurs

Robert A Sorabella (RA)

9967Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Luz Padilla (L)

9967Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Jonathan W Byrnes (JW)

Division of Pediatric Cardiology, Department of Pediatrics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Joseph Timpa (J)

22078Department of Cardiovascular Perfusion Children's of Alabama, Birmingham, AL, USA.

Carlisle O'Meara (C)

22078Department of Cardiovascular Perfusion Children's of Alabama, Birmingham, AL, USA.

Joseph R Buckman (JR)

9967Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Kathryn Maxwell (K)

9967Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Santiago Borasino (S)

Division of Pediatric Cardiology, Department of Pediatrics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Hayden Zaccagni (H)

Division of Pediatric Cardiology, Department of Pediatrics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Ahmed Asfari (A)

Division of Pediatric Cardiology, Department of Pediatrics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Mark A Law (MA)

Division of Pediatric Cardiology, Department of Pediatrics, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

David C Cleveland (DC)

9967Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Robert J Dabal (RJ)

9967Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

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Classifications MeSH