Brazilian network of COVID-19 during pregnancy (REBRACO: a multicentre study protocol).
COVID-19
infection control
maternal medicine
prenatal diagnosis
qualitative research
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
17 12 2021
17 12 2021
Historique:
entrez:
18
12
2021
pubmed:
19
12
2021
medline:
31
12
2021
Statut:
epublish
Résumé
The aim of this study was to evaluate the clinical, epidemiological and laboratory aspects of SARS-CoV-2 infection during pregnancy and postpartum in 16 maternity hospitals. A prospective multicentre study, with five axes. First, the prevalence of SARS-CoV-2 infection among women admitted for childbirth will be described in a cross-sectional study. Second, maternal and perinatal outcomes will be assessed in a prospective cohort study including pregnant or postpartum women with suspected COVID-19. Third, a cohort of positive COVID-19 cases with sampling of a variety of biological material. Histopathological and viral analysis of biological maternal and neonatal samples will be performed, and the assessment of nutritional variables to evaluate the association between vitamin D and severity of infection. Fourth, a monitoring and evaluation committee to collect relevant healthcare information and plan actions in centres facing the pandemic. Furthermore, qualitative studies will be performed to study pregnant women, their families and health professionals. Fifth, an ecological study will monitor the number of live births, stillbirths and other outcomes to explore any trend among the periods before, during and after the pandemic. Data will systematically be collected in an electronic platform following standardised operational procedures. For quantitative study components, an appropriate statistical approach will be used for each analysis. For qualitative data, in-depth interviews recorded in audio will be transcribed, checking the text obtained with the recording. Subsequently, thematic analysis with the aid of the NVivo programme will be performed. Ethical approval was obtained (letters of approval numbers 4.047.168, 4.179.679 and 4.083.988). All women will be fully informed to sign the consent form before enrolment in the study. Findings will be disseminated through peer-reviewed journals and scientific conferences.
Identifiants
pubmed: 34921076
pii: bmjopen-2021-051284
doi: 10.1136/bmjopen-2021-051284
pmc: PMC8685531
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e051284Investigateurs
Sherly Metelus
(S)
Lester Castro
(L)
Stephanie Pabon
(S)
Rachel Soeiro
(R)
Amanda D Silva
(AD)
Paulo S R Junior
(PSR)
Thais G Sardinha
(TG)
Rodolfo R Japenga
(RR)
Erica R F Urquiza
(ERF)
Maíra R Machado
(MR)
Marcela Maria Simões
(MM)
Larissa M Solda
(LM)
Jussara Mayrink
(J)
Sue Yazaki-Sun
(S)
Priscilla Mota
(P)
Arimaza C Soares
(AC)
Ellen Machado
(E)
Anne Bergmann
(A)
Gustavo Raupp Dos Santos
(GRD)
Patrícia B Peres
(PB)
Cristiane L Arbeli
(CL)
Rafael M Quevedo
(RM)
Carolina F Yamashita
(CF)
Julia D Corradin
(JD)
Isabella Bergamini
(I)
José Geraldo L Ramos
(JG)
Maria Lúcia R Oppermann
(ML)
Laisa S Quadro
(LS)
Lina Marins
(L)
Érika V Paniz
(ÉV)
Thaís Vicentini Xavier
(TV)
Bruna E Parreira
(BE)
Aline Tosetto
(A)
Sabrina Savazoni
(S)
Aline C Costa
(AC)
Marina Hl Almeida
(MH)
Bruna Fv Moura
(BF)
Lidiane R França
(LR)
Hanna Vieira
(H)
Rafael B Aquino
(R)
Débora F Leite
(DF)
Isabella Monteiro
(I)
Marcos Nakamura-Pereira
(M)
Bruna O Guerra
(BO)
Gabriela Gorga
(G)
Daisy Pinheiro
(D)
Denise Cordeiro
(D)
Priscila L Miná
(PL)
Carol Dornellas
(C)
Kevin Fa Oliveira
(KF)
Caio Leal
(C)
Rayra Amana
(R)
Cristiane O Santos
(CO)
Marina M Dos Santos
(MM)
Carlos Neto
(C)
Thiago Gomes
(T)
Isabela R Pereira
(IR)
Clélia Andrade Salustrino
(CA)
Valéria B Pontes
(VB)
Roberto Allen da Silva Franco
(RA)
João Paolo Bilibio
(JP)
Gislânia Pf Brito
(GP)
Hana Paula C Pinto
(HP)
Danielle Leal de Oliveira
(DL)
Andrezza A Guerra
(AA)
Andrea O Moura
(AO)
Natasha Pantoja
(N)
Fernanda David
(F)
Alina Silva
(A)
Juliana Vasconcellos Freitas-Jesus
(JV)
Angela M Bacha
(AM)
Anderson Borovac-Pinheiro
(A)
Belmiro G Pereira
(BG)
Eliana M Amaral
(EM)
Elton Carlos Ferreira
(EC)
Helaine Mbpm Milanez
(HM)
Jamil P S Caldas
(JPS)
Luiz F Baccaro
(LF)
Marcelo L Nomura
(ML)
Patrícia M Rehder
(PM)
Renata Z Simone
(RZ)
Renato Passini
(R)
Cristiano Torrezan
(C)
Jose L P Modena
(JLP)
Magnun N Nunes Dos Santos
(MN)
Sergio T M Marba
(STM)
Tabata Z Dias
(TZ)
Mariana Ev
(M)
Informations de copyright
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
BJOG. 2016 May;123(6):946-53
pubmed: 26412586
Int J Gynaecol Obstet. 2020 Oct;151(1):154-156
pubmed: 32644220
J Matern Fetal Neonatal Med. 2020 Jul 16;:1-7
pubmed: 32674646
Nat Med. 2020 Apr;26(4):450-452
pubmed: 32284615
Biomed Res Int. 2019 Jan 16;2019:5476350
pubmed: 30775382
J Korean Med Sci. 2017 Oct;32(10):1717-1720
pubmed: 28875620
Nat Commun. 2020 Jul 14;11(1):3572
pubmed: 32665677
J Infect Dis. 2020 May 11;221(11):1770-1774
pubmed: 32179910
BMC Endocr Disord. 2013 Apr 29;13:14
pubmed: 23627369
Rev Bras Ginecol Obstet. 2021 May;43(5):377-383
pubmed: 34182582
Int J Gynaecol Obstet. 2020 Aug;150(2):260-261
pubmed: 32412120
Arch Pathol Lab Med. 2016 Jul;140(7):698-713
pubmed: 27223167
Lancet. 2020 Jun 6;395(10239):1757-1758
pubmed: 32446324
Am J Obstet Gynecol MFM. 2020 Nov;2(4):100214
pubmed: 32838279
Ultrasound Obstet Gynecol. 2020 May;55(5):586-592
pubmed: 32180292
Anal Biochem. 1977 May 15;80(1):298-305
pubmed: 883638
J Perinat Med. 2020 Nov 26;48(9):950-958
pubmed: 32975205
Eur J Nutr. 2018 Apr;57(3):1059-1072
pubmed: 28353072
BJOG. 2020 Dec;127(13):1618-1626
pubmed: 32799381
Cad Saude Publica. 2010 Nov;26(11):2039-49
pubmed: 21180977
Lancet Child Adolesc Health. 2018 Mar;2(3):223-228
pubmed: 30169257
BMC Infect Dis. 2016 Mar 02;16:105
pubmed: 26936356
ScientificWorldJournal. 2015;2015:719104
pubmed: 25759862
Public Health Nutr. 2013 Aug;16(8):1419-26
pubmed: 22895030