Dynamic interaction network involving the conserved intrinsically disordered regions in human eIF5.

Dynamic interactions Intrinsically disordered region (IDR) NMR Protein-protein interactions Translation initiation eIF5

Journal

Biophysical chemistry
ISSN: 1873-4200
Titre abrégé: Biophys Chem
Pays: Netherlands
ID NLM: 0403171

Informations de publication

Date de publication:
02 2022
Historique:
received: 01 10 2021
revised: 05 12 2021
accepted: 06 12 2021
pubmed: 20 12 2021
medline: 19 4 2022
entrez: 19 12 2021
Statut: ppublish

Résumé

Translation initiation in eukaryotes requires multiple eukaryotic translation initiation factors (eIFs) and involves continuous remodeling of the ribosomal preinitiation complex (PIC). The GTPase eIF2 brings the initiator Met-tRNA

Identifiants

pubmed: 34923394
pii: S0301-4622(21)00223-4
doi: 10.1016/j.bpc.2021.106740
pmc: PMC8741751
mid: NIHMS1765042
pii:
doi:

Substances chimiques

Eukaryotic Initiation Factor-2 0
Eukaryotic Initiation Factor-5 0
Eukaryotic Initiation Factors 0
eukaryotic initiation factor-5B 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

106740

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM134113
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

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Auteurs

Eleanor Elise Paul (EE)

Department of Physiology & Biophysics, Boston University School of Medicine, 700 Albany St. W336, Boston, MA 02118, USA.

Kay Ying Lin (KY)

Department of Physiology & Biophysics, Boston University School of Medicine, 700 Albany St. W336, Boston, MA 02118, USA.

Nathan Gamble (N)

Department of Physiology & Biophysics, Boston University School of Medicine, 700 Albany St. W336, Boston, MA 02118, USA.

Amy Wei-Lun Tsai (AW)

Department of Physiology & Biophysics, Boston University School of Medicine, 700 Albany St. W336, Boston, MA 02118, USA.

Simon H K Swan (SHK)

Department of Physiology & Biophysics, Boston University School of Medicine, 700 Albany St. W336, Boston, MA 02118, USA.

Yu Yang (Y)

Department of Physiology & Biophysics, Boston University School of Medicine, 700 Albany St. W336, Boston, MA 02118, USA.

Matthew Doran (M)

Department of Physiology & Biophysics, Boston University School of Medicine, 700 Albany St. W336, Boston, MA 02118, USA.

Assen Marintchev (A)

Department of Physiology & Biophysics, Boston University School of Medicine, 700 Albany St. W336, Boston, MA 02118, USA. Electronic address: amarint@bu.edu.

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Classifications MeSH