An Exquisite Case of Giant Occipital Meningocele Following Aplasia of Occipital Bone.

Cephaloceles are the neural tube defects occurring at a rate of one per 5 000 live births worldwide. It indicates herniation of meninges or meninges with brain tissue through defect in the cranium. We describe an interesting case report of a one-day old male neonate with giant occipital meningocele with aplasia of occipital bone. This is the first case with a history of consanguinity reported in the literature so far. The size of the meningocele sac was greater than the that of the head. A plain computed tomography of the brain showed a 136 mm x 129 mm well defined cerebrospinal fluid attenuated hypodense lesion herniating through calvaria defect on occipital region, with no neural elements, suggestive of giant occipital meningocele. All efforts should be made to diagnose cranial or spinal dysraphism during antenatal screening meticulously following a careful history taking, clinical examination and ultrasonography scan in the first trimester, followed by folic acid supplementation, mandatory through legislation.