A Case of Hypopharyngeal Cancer Associated With Fanconi Anemia: A Helical Tomotherapy Experience.
aplastic anemia
cetuximab
concomitant chemo-radiation therapy
fanconi anemia
head and neck squamous cell cancer
helical imrt
radiation therapy
tomotherapy
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
accepted:
08
11
2021
entrez:
20
12
2021
pubmed:
21
12
2021
medline:
21
12
2021
Statut:
epublish
Résumé
Fanconi anemia (FA) is a disease that could be accompanied by multiple abnormalities, such as growth retardation, bone marrow abnormalities, and cancer susceptibility. Among the FA patients, head and neck squamous cell cancer (HNSCC) is the most observed solid cancer. The life expectancy of patients with FA has increased with recent medical advances. Furthermore, HNSCC is diagnosed in 3% of FA patients, and half of these patients die because of their HNSCC. The median age of HNSCC patients with FA is 31, and according to the literature HNSCC incidence of FA, patients is more than 700-fold of the normal population. Here, we reported the treatment details and challenges we faced during hypopharyngeal cancer treatment in a FA patient.
Identifiants
pubmed: 34925988
doi: 10.7759/cureus.19386
pmc: PMC8654145
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e19386Informations de copyright
Copyright © 2021, Kavak et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Head Neck. 2019 May;41(5):1418-1426
pubmed: 30633423
Curr Opin Cell Biol. 2015 Dec;37:49-60
pubmed: 26512453
Nature. 2011 Jul 06;475(7354):53-8
pubmed: 21734703
Blood Rev. 2010 May;24(3):101-22
pubmed: 20417588
Am J Pediatr Hematol Oncol. 1992 May;14(2):177-85
pubmed: 1530124
Nature. 2012 Sep 27;489(7417):571-5
pubmed: 22922648
Front Pediatr. 2019 Oct 31;7:443
pubmed: 31737588
Arch Otolaryngol Head Neck Surg. 2003 Jan;129(1):106-12
pubmed: 12525204
J Laryngol Otol. 1991 Feb;105(2):125-7
pubmed: 2013724
Laryngoscope. 2016 Apr;126(4):870-9
pubmed: 26484938
Head Neck. 2013 Oct;35(10):E292-8
pubmed: 22965917
Eur J Cancer B Oral Oncol. 1995 Jan;31B(1):68-72
pubmed: 7627092
Genes Dev. 2012 Jul 1;26(13):1393-408
pubmed: 22751496
Blood. 2003 Feb 15;101(4):1249-56
pubmed: 12393516
Blood. 1995 Oct 1;86(7):2856-62
pubmed: 7670120
Cell Res. 2008 Jan;18(1):99-113
pubmed: 18166982