A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties.
2H-chromen-2-one
biological activity
coumarin
fluorescent properties
metal complexes
Journal
Frontiers in chemistry
ISSN: 2296-2646
Titre abrégé: Front Chem
Pays: Switzerland
ID NLM: 101627988
Informations de publication
Date de publication:
2021
2021
Historique:
received:
23
09
2021
accepted:
08
11
2021
entrez:
20
12
2021
pubmed:
21
12
2021
medline:
21
12
2021
Statut:
epublish
Résumé
The coumarin nucleus is a recurring motif in both natural and synthetic compounds that exhibit a broad spectrum of biological properties including anticoagulant, anti-inflammatory, antioxidant, antiviral, antimicrobial and anticancer agents as well as enzyme inhibitors. On the other hand, it has been reported that the incorporation of a metal ion into coumarin derivatives can increase the activity of such complexes compared to coumarin-based ligands. Accordingly, some of them have been found to display promising antioxidant, antitumor or antibacterial activities. This mini-review briefly summarizes the recent development of coumarin-metal complexes with proven biological properties. The attention is also paid to agents for which practical applications in the detection of biologically important species may be found.
Identifiants
pubmed: 34926402
doi: 10.3389/fchem.2021.781779
pii: 781779
pmc: PMC8671816
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
781779Informations de copyright
Copyright © 2021 Balewski, Szulta, Jalińska and Kornicka.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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