Berry anthocyanidins inhibit intestinal polyps and colon tumors by modulation of Src, EGFR and the colon inflammatory environment.
PD-L1
anthocyanidins
bilberry
colorectal cancer
familial adenomatous polyposis
Journal
Oncoscience
ISSN: 2331-4737
Titre abrégé: Oncoscience
Pays: United States
ID NLM: 101636666
Informations de publication
Date de publication:
2021
2021
Historique:
received:
03
06
2021
accepted:
01
12
2021
entrez:
20
12
2021
pubmed:
21
12
2021
medline:
21
12
2021
Statut:
epublish
Résumé
Colorectal cancer is the third most common form of cancer diagnosed and the third leading class for cancer-related deaths. Given the prevalence of colon cancer worldwide, further insight into developing novel and effective prevention and treatment strategies are warranted. The family of plant pigments known as the anthocyanins has been identified with a variety of health benefits including chemopreventive and therapeutic effects. A limitation to current clinical applications of anthocyanins is the high doses that are required. In order to overcome this limitation, we tested the active moiety, anthocyanidins for chemopreventive and therapeutic effects against colorectal cancer
Identifiants
pubmed: 34926717
doi: 10.18632/oncoscience.548
pii: 548
pmc: PMC8664094
doi:
Types de publication
Journal Article
Langues
eng
Pagination
120-133Déclaration de conflit d'intérêts
CONFLICTS OF INTEREST The authors have no conflicts of interest to declare.
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