The Vaginal Microbiome: III. The Vaginal Microbiome in Various Urogenital Disorders.
Journal
Journal of lower genital tract disease
ISSN: 1526-0976
Titre abrégé: J Low Genit Tract Dis
Pays: United States
ID NLM: 9704963
Informations de publication
Date de publication:
01 Jan 2022
01 Jan 2022
Historique:
entrez:
20
12
2021
pubmed:
21
12
2021
medline:
24
12
2021
Statut:
ppublish
Résumé
This series of articles, titled The Vaginal Microbiome (VMB), written on behalf of the International Society for the Study of Vulvovaginal Disease, aims to summarize the recent findings and understanding of the vaginal bacterial microbiota, mainly regarding areas relevant to clinicians specializing in vulvovaginal disorders. A search of PubMed database was performed, using the search terms "vaginal microbiome" with "Candida," "vaginitis," "urinary microbiome," "recurrent urinary tract infections," "sexually transmitted infections," "human immunodeficiency virus," "human papillomavirus," "nonspecific vaginitis," "vulvodynia," and "vulvovaginal symptoms." Full article texts were reviewed. Reference lists were screened for additional articles. The third article in this series describes VMB in various urogenital disorders. Variable patterns of the VMB are found in patients with vulvovaginal candidiasis, challenging the idea of a protective role of lactobacilli. Highly similar strains of health-associated commensal bacteria are shared in both the bladder and vagina of the same individual and may provide protection against urinary tract infections. Dysbiotic VMB increases the risk of urinary tract infection. Loss of vaginal lactic acid-producing bacteria combined with elevated pH, increase the risk for sexually transmitted infections, although the exact protective mechanisms of the VMB against sexually transmitted infections are still unknown. The VMB may constitute a biological barrier to pathogenic microorganisms. When the predominance of lactobacilli community is disrupted, there is an increased risk for the acquisition of various vaginal pathogents. Longitudinal studies are needed to describe the association between the host, bacterial, and fungal components of the VMB.
Identifiants
pubmed: 34928258
doi: 10.1097/LGT.0000000000000645
pii: 00128360-202201000-00017
pmc: PMC8719503
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
85-92Informations de copyright
Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the ASCCP.
Déclaration de conflit d'intérêts
The authors have declared they have no conflicts of interest.
Références
PLoS One. 2013 Nov 12;8(11):e79812
pubmed: 24265786
Sci Rep. 2017 Aug 31;7(1):10200
pubmed: 28860468
Obstet Gynecol. 2003 Sep;102(3):527-34
pubmed: 12962937
J Med Virol. 1994 Jun;43(2):194-200
pubmed: 8083669
Sex Transm Dis. 2020 Apr;47(4):269-274
pubmed: 32044865
Microb Cell. 2019 Nov 25;7(1):1-14
pubmed: 31921929
Virulence. 2017 Apr 3;8(3):342-351
pubmed: 27657355
Cell. 2015 Oct 8;163(2):367-80
pubmed: 26411289
AIDS. 2013 Oct;27 Suppl 1:S5-15
pubmed: 24088684
Sex Transm Dis. 2008 Apr;35(4):363-7
pubmed: 18360319
J Leukoc Biol. 1999 Aug;66(2):252-62
pubmed: 10449163
Ann Clin Microbiol Antimicrob. 2020 Jan 28;19(1):5
pubmed: 31992328
J Infect Dis. 2005 Apr 1;191(7):1129-39
pubmed: 15747249
J Infect Dis. 1999 Dec;180(6):1950-6
pubmed: 10558952
Pathog Dis. 2014 Dec;72(3):161-6
pubmed: 24961922
J Urol. 1994 Sep;152(3):831-3
pubmed: 8051730
Eur J Clin Microbiol Infect Dis. 2009 Mar;28(3):281-5
pubmed: 18762999
Curr Opin Microbiol. 2017 Dec;40:58-64
pubmed: 29132066
J Infect Dis. 2010 Dec 15;202(12):1907-15
pubmed: 21067371
Contraception. 2000 Sep;62(3):107-12
pubmed: 11124356
Int J STD AIDS. 2003 Jan;14(1):30-6
pubmed: 12590790
Am J Obstet Gynecol. 2019 Jan;220(1):91.e1-91.e8
pubmed: 30595144
AIDS Res Ther. 2007 Oct 22;4:25
pubmed: 17953761
Infect Dis Obstet Gynecol. 2012;2012:287849
pubmed: 22675241
Am J Epidemiol. 2000 Jun 15;151(12):1194-205
pubmed: 10905532
mBio. 2019 Oct 15;10(5):
pubmed: 31615961
J Infect Dis. 2009 Aug 15;200(4):528-36
pubmed: 19586416
Mycoses. 2009 Jan;52(1):1-10
pubmed: 18983434
PLoS One. 2015 Jun 16;10(6):e0129795
pubmed: 26079509
Sci Rep. 2019 Oct 1;9(1):14095
pubmed: 31575935
Am J Obstet Gynecol. 2020 Sep;223(3):406.e1-406.e16
pubmed: 32135142
Sex Transm Dis. 2008 Jan;35(1):78-83
pubmed: 17989585
Microbiol Spectr. 2016 Dec;4(6):
pubmed: 28087949
Histol Histopathol. 2014 May;29(5):567-87
pubmed: 24327088
Rev Infect Dis. 1990 Sep-Oct;12(5):856-72
pubmed: 2237129
Lancet. 1997 Aug 23;350(9077):546-50
pubmed: 9284776
J Urol. 1981 Nov;126(5):630-4
pubmed: 7029007
J Sex Med. 2016 Apr;13(4):607-12
pubmed: 27045260
Clin Infect Dis. 2018 Aug 31;67(6):e1-e94
pubmed: 29955859
J Fungi (Basel). 2020 Jan 17;6(1):
pubmed: 31963458
BJOG. 2021 Mar;128(4):768
pubmed: 33241645
Immunity. 2017 Jan 17;46(1):29-37
pubmed: 28087240
J Low Genit Tract Dis. 2017 Apr;21(2):150-156
pubmed: 27984345
Am J Obstet Gynecol. 2016 Jan;214(1):15-21
pubmed: 26164695
Curr Infect Dis Rep. 2000 Dec;2(6):513-517
pubmed: 11095901
Genome Biol. 2012 Jun 14;13(6):R42
pubmed: 22698087
Virulence. 2013 Feb 15;4(2):119-28
pubmed: 23302789
Clin Vaccine Immunol. 2009 Jan;16(1):29-36
pubmed: 19020112
J Low Genit Tract Dis. 2020 Jul;24(3):290-294
pubmed: 32205761
Infect Immun. 2009 Sep;77(9):4130-5
pubmed: 19528218
JAMA. 1991 Jan 2;265(1):64-9
pubmed: 1859519
Front Immunol. 2017 Jun 07;8:629
pubmed: 28638380
Clin Infect Dis. 2003 Aug 1;37(3):319-25
pubmed: 12884154
J Infect Dis. 2005 Jan 1;191(1):25-32
pubmed: 15592999
J Infect Dis. 2003 Oct 1;188(7):1054-8
pubmed: 14513427
Curr Issues Mol Biol. 2011;13(2):25-36
pubmed: 21220789
Clin Infect Dis. 2015 Jul 15;61(2):260-9
pubmed: 25900168
BJOG. 2020 Jan;127(2):171-180
pubmed: 31237400
PLoS One. 2013;8(1):e54379
pubmed: 23372716
mBio. 2015 Oct 06;6(5):e01084-15
pubmed: 26443453
J Lab Physicians. 2016 Jan-Jun;8(1):5-18
pubmed: 27013807
Trends Microbiol. 2018 Apr;26(4):284-295
pubmed: 29452950
J Infect Dis. 2016 Nov 1;214(9):1361-1369
pubmed: 27521363
Am J Obstet Gynecol. 2020 May;222(5):471.e1-471.e9
pubmed: 31654610
AIDS Res Hum Retroviruses. 2019 Mar;35(3):219-228
pubmed: 30638028
World J Clin Oncol. 2014 Oct 10;5(4):753-63
pubmed: 25302175
Sci Rep. 2015 Nov 17;5:16865
pubmed: 26574055
BJOG. 2015 Jan;122(2):213-8
pubmed: 25316066
Front Microbiol. 2019 Jan 08;9:3265
pubmed: 30671051
J Infect Dis. 2000 Feb;181(2):595-601
pubmed: 10669343
PLoS One. 2014 Aug 22;9(8):e105998
pubmed: 25148517
Med Hypotheses. 2013 Aug;81(2):228-30
pubmed: 23707510
J Infect Dis. 2007 Dec 1;196(11):1692-7
pubmed: 18008255
Microorganisms. 2020 Jan 21;8(2):
pubmed: 31972980
Cell. 2018 Aug 9;174(4):785-790
pubmed: 30096310
J Infect Dis. 1999 Dec;180(6):1863-8
pubmed: 10558942
Clin Infect Dis. 2005 May 15;40(10):1422-8
pubmed: 15844064
PLoS One. 2016 Apr 26;11(4):e0153274
pubmed: 27115350
J Acquir Immune Defic Syndr. 2005 Jul 1;39(3):340-6
pubmed: 15980696
Acta Derm Venereol. 2007;87(4):350-4
pubmed: 17598040
Int Urogynecol J. 2018 Dec;29(12):1775-1782
pubmed: 29946828
Nat Commun. 2018 Apr 19;9(1):1557
pubmed: 29674608
J Clin Med Res. 2018 Sep;10(9):688-692
pubmed: 30116438
Obstet Gynecol. 2017 Apr;129(4):643-654
pubmed: 28277350
Lancet Infect Dis. 2017 Dec;17(12):1303-1316
pubmed: 28843576
Lancet Infect Dis. 2008 Aug;8(8):490-7
pubmed: 18652995
J Fungi (Basel). 2020 Feb 25;6(1):
pubmed: 32106438
Clin Infect Dis. 2019 Jan 18;68(3):375-381
pubmed: 30084883
Nat Microbiol. 2016 Dec 12;2:16238
pubmed: 27941860
J Fungi (Basel). 2021 Feb 06;7(2):
pubmed: 33562068
PLoS Pathog. 2017 May 22;13(5):e1006403
pubmed: 28542528
J Infect Dis. 2009 Jun 15;199(12):1883-90
pubmed: 19456235
JAMA. 2004 Mar 17;291(11):1368-79
pubmed: 15026404
Biochim Biophys Acta Mol Basis Dis. 2020 Jan 1;1866(1):165534
pubmed: 31634534
Infect Dis Clin North Am. 1997 Sep;11(3):531-49
pubmed: 9378922
J Womens Health (Larchmt). 2017 Oct;26(10):1069-1076
pubmed: 28686502
PLoS Pathog. 2017 Mar 30;13(3):e1006238
pubmed: 28358889
Maturitas. 2016 Sep;91:42-50
pubmed: 27451320
Microorganisms. 2019 Oct 16;7(10):
pubmed: 31623187
J Fungi (Basel). 2018 Sep 18;4(3):
pubmed: 30231476
World J Urol. 2020 Nov;38(11):2721-2731
pubmed: 32006175
Popul Health Manag. 2020 Oct;23(S1):S3-S12
pubmed: 32997581
Curr Infect Dis Rep. 2019 Nov 9;21(11):44
pubmed: 31707496
J Infect Dis. 2015 Dec 15;212(12):1856-61
pubmed: 26080369
Viral Immunol. 2006 Summer;19(3):481-91
pubmed: 16987066
Am J Obstet Gynecol. 2007 Jun;196(6):517.e1-6
pubmed: 17547876
Mol Urol. 2001 Spring;5(1):31-6
pubmed: 11689149
Mucosal Immunol. 2017 Nov;10(6):1480-1490
pubmed: 28401934
J Clin Microbiol. 1989 Feb;27(2):251-6
pubmed: 2915019
Nucleic Acids Res. 2012 Apr;40(8):3548-62
pubmed: 22187158
AIDS. 1995 Sep;9(9):1093-7
pubmed: 8527084
Sci Rep. 2018 Feb 2;8(1):2307
pubmed: 29396486
Infect Immun. 2013 Jan;81(1):238-48
pubmed: 23115042