High Prevalence of OXA-23 Carbapenemase-Producing
Acinetobacter
OXA-23
Proteae
carbapenemase
epidemiology
infectious clones
Journal
Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061
Informations de publication
Date de publication:
15 02 2022
15 02 2022
Historique:
pubmed:
22
12
2021
medline:
23
3
2022
entrez:
21
12
2021
Statut:
ppublish
Résumé
In this multicentric study performed in 12 French hospitals, we reported that 26.9% (14/52) of the amoxicillin-clavulanate-resistant Proteus mirabilis isolates produced the OXA-23 carbapenemase. We found that an inhibition zone diameter of <11 mm around the amoxicillin-clavulanate disc was an accurate screening cutoff to detect these OXA-23 producers. We confirmed by whole-genome sequencing that these OXA-23-producers all belonged to the same lineage that has been demonstrated to disseminate OXA-23 or OXA-58 in P. mirabilis.
Identifiants
pubmed: 34930033
doi: 10.1128/AAC.01983-21
pmc: PMC8846483
doi:
Substances chimiques
Anti-Bacterial Agents
0
Bacterial Proteins
0
Amoxicillin-Potassium Clavulanate Combination
74469-00-4
beta-Lactamases
EC 3.5.2.6
carbapenemase
EC 3.5.2.6
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0198321Références
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