Enantioselective Fluorination of α-Substituted β-Diketones Using β,β-Diaryl Serines.
Journal
Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393
Informations de publication
Date de publication:
14 01 2022
14 01 2022
Historique:
pubmed:
22
12
2021
medline:
22
12
2021
entrez:
21
12
2021
Statut:
ppublish
Résumé
We report the enantioselective fluorination of α-substituted β-diketones using β,β-diaryl serines as a primary amine organocatalyst. The reaction affords the corresponding fluorinated products in yields of 74 to 99% with excellent enantioselectivity (75-95%
Identifiants
pubmed: 34931846
doi: 10.1021/acs.orglett.1c04104
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM