An Integrated Model to Improve Medication Reconciliation in Oncology: Prospective Interventional Study.

IT platform community pharmacies drug incompatibility drug interactions healthcare transitions information technology medication recognition medication reconciliation oncology pharmacy

Journal

Journal of medical Internet research
ISSN: 1438-8871
Titre abrégé: J Med Internet Res
Pays: Canada
ID NLM: 100959882

Informations de publication

Date de publication:
20 12 2021
Historique:
received: 29 06 2021
accepted: 29 10 2021
revised: 21 09 2021
entrez: 21 12 2021
pubmed: 22 12 2021
medline: 28 12 2021
Statut: epublish

Résumé

Accurate medication reconciliation reduces the risk of drug incompatibilities and adverse events that can occur during transitions in care. Community pharmacies (CPs) are a crucial part of the health care system and could be involved in collecting essential information on conventional and supplementary drugs used at home. The aim of this paper was to establish an alliance between our cancer institute, Istituto Romagnolo per lo Studio dei Tumori (IRST), and CPs, the latter entrusted with the completion of a pharmacological recognition survey. We also aimed to integrate the national information technology (IT) platform of CPs with the electronic medical records of IRST. Cancer patients undergoing antiblastic treatments were invited to select a CP taking part in the study and to complete the pharmacological recognition step. The information collected by the pharmacist was sent to the electronic medical records of IRST through the new IT platform, after which the oncologist performed the reconciliation process. A total of 66 CPs completed surveys for 134 patients. An average of 5.9 drugs per patient was used at home, with 12 or more used in the most advanced age groups. Moreover, 60% (80/134) of the patients used nonconventional products or critical foods. Some potential interactions between nonconventional medications and cancer treatments were reported. In the PROF-1 (Progetto di Rete in Oncologia con le Farmacie di comunità della Romagna) study, an alliance was created between our cancer center and CPs to improve medication reconciliation, and a new integrated IT platform was validated. ClinicalTrials.gov NCT04796142; https://clinicaltrials.gov/ct2/show/NCT04796142.

Sections du résumé

BACKGROUND
Accurate medication reconciliation reduces the risk of drug incompatibilities and adverse events that can occur during transitions in care. Community pharmacies (CPs) are a crucial part of the health care system and could be involved in collecting essential information on conventional and supplementary drugs used at home.
OBJECTIVE
The aim of this paper was to establish an alliance between our cancer institute, Istituto Romagnolo per lo Studio dei Tumori (IRST), and CPs, the latter entrusted with the completion of a pharmacological recognition survey. We also aimed to integrate the national information technology (IT) platform of CPs with the electronic medical records of IRST.
METHODS
Cancer patients undergoing antiblastic treatments were invited to select a CP taking part in the study and to complete the pharmacological recognition step. The information collected by the pharmacist was sent to the electronic medical records of IRST through the new IT platform, after which the oncologist performed the reconciliation process.
RESULTS
A total of 66 CPs completed surveys for 134 patients. An average of 5.9 drugs per patient was used at home, with 12 or more used in the most advanced age groups. Moreover, 60% (80/134) of the patients used nonconventional products or critical foods. Some potential interactions between nonconventional medications and cancer treatments were reported.
CONCLUSIONS
In the PROF-1 (Progetto di Rete in Oncologia con le Farmacie di comunità della Romagna) study, an alliance was created between our cancer center and CPs to improve medication reconciliation, and a new integrated IT platform was validated.
TRIAL REGISTRATION
ClinicalTrials.gov NCT04796142; https://clinicaltrials.gov/ct2/show/NCT04796142.

Identifiants

pubmed: 34932001
pii: v23i12e31321
doi: 10.2196/31321
pmc: PMC8726040
doi:

Banques de données

ClinicalTrials.gov
['NCT04796142']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e31321

Informations de copyright

©Alessandro Passardi, Patrizia Serra, Caterina Donati, Federica Fiori, Sabrina Prati, Roberto Vespignani, Gabriele Taglioni, Patrizia Farfaneti Ghetti, Giovanni Martinelli, Oriana Nanni, Mattia Altini, Giovanni Luca Frassineti, Martina Vittoria Minguzzi. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 20.12.2021.

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Auteurs

Alessandro Passardi (A)

Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

Patrizia Serra (P)

Unit of Biostatistics and Clinical Trials, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

Caterina Donati (C)

Oncology Pharmacy Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

Federica Fiori (F)

Oncology Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

Sabrina Prati (S)

Oncology Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

Roberto Vespignani (R)

IT Service, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

Gabriele Taglioni (G)

A.S.SO.FARM Community Pharmacy, Ravenna, Italy.

Patrizia Farfaneti Ghetti (P)

Federfarma Community Pharmacy, Rimini, Italy.

Giovanni Martinelli (G)

Hematology Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

Oriana Nanni (O)

Unit of Biostatistics and Clinical Trials, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

Mattia Altini (M)

Healthcare Administration, Azienda Unità Sanitaria Locale (AUSL) Romagna, Ravenna, Italy.

Giovanni Luca Frassineti (GL)

Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

Martina Vittoria Minguzzi (MV)

Healthcare Administration, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy.

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