Exploring the Effects of In-App Components on Engagement With a Symptom-Tracking Platform Among Participants With Major Depressive Disorder (RADAR-Engage): Protocol for a 2-Armed Randomized Controlled Trial.

app engagement major depressive disorder mobile phone remote measurement technologies research

Journal

JMIR research protocols
ISSN: 1929-0748
Titre abrégé: JMIR Res Protoc
Pays: Canada
ID NLM: 101599504

Informations de publication

Date de publication:
21 Dec 2021
Historique:
received: 05 08 2021
accepted: 14 10 2021
revised: 13 10 2021
entrez: 21 12 2021
pubmed: 22 12 2021
medline: 22 12 2021
Statut: epublish

Résumé

Multi-parametric remote measurement technologies (RMTs) comprise smartphone apps and wearable devices for both active and passive symptom tracking. They hold potential for understanding current depression status and predicting future depression status. However, the promise of using RMTs for relapse prediction is heavily dependent on user engagement, which is defined as both a behavioral and experiential construct. A better understanding of how to promote engagement in RMT research through various in-app components will aid in providing scalable solutions for future remote research, higher quality results, and applications for implementation in clinical practice. The aim of this study is to provide the rationale and protocol for a 2-armed randomized controlled trial to investigate the effect of insightful notifications, progress visualization, and researcher contact details on behavioral and experiential engagement with a multi-parametric mobile health data collection platform, Remote Assessment of Disease and Relapse (RADAR)-base. We aim to recruit 140 participants upon completion of their participation in the RADAR Major Depressive Disorder study in the London site. Data will be collected using 3 weekly tasks through an active smartphone app, a passive (background) data collection app, and a Fitbit device. Participants will be randomly allocated at a 1:1 ratio to receive either an adapted version of the active app that incorporates insightful notifications, progress visualization, and access to researcher contact details or the active app as usual. Statistical tests will be used to assess the hypotheses that participants using the adapted app will complete a higher percentage of weekly tasks (behavioral engagement: primary outcome) and score higher on self-awareness measures (experiential engagement). Recruitment commenced in April 2021. Data collection was completed in September 2021. The results of this study will be communicated via publication in 2022. This study aims to understand how best to promote engagement with RMTs in depression research. The findings will help determine the most effective techniques for implementation in both future rounds of the RADAR Major Depressive Disorder study and, in the long term, clinical practice. ClinicalTrials.gov NCT04972474; http://clinicaltrials.gov/ct2/show/NCT04972474. DERR1-10.2196/32653.

Sections du résumé

BACKGROUND BACKGROUND
Multi-parametric remote measurement technologies (RMTs) comprise smartphone apps and wearable devices for both active and passive symptom tracking. They hold potential for understanding current depression status and predicting future depression status. However, the promise of using RMTs for relapse prediction is heavily dependent on user engagement, which is defined as both a behavioral and experiential construct. A better understanding of how to promote engagement in RMT research through various in-app components will aid in providing scalable solutions for future remote research, higher quality results, and applications for implementation in clinical practice.
OBJECTIVE OBJECTIVE
The aim of this study is to provide the rationale and protocol for a 2-armed randomized controlled trial to investigate the effect of insightful notifications, progress visualization, and researcher contact details on behavioral and experiential engagement with a multi-parametric mobile health data collection platform, Remote Assessment of Disease and Relapse (RADAR)-base.
METHODS METHODS
We aim to recruit 140 participants upon completion of their participation in the RADAR Major Depressive Disorder study in the London site. Data will be collected using 3 weekly tasks through an active smartphone app, a passive (background) data collection app, and a Fitbit device. Participants will be randomly allocated at a 1:1 ratio to receive either an adapted version of the active app that incorporates insightful notifications, progress visualization, and access to researcher contact details or the active app as usual. Statistical tests will be used to assess the hypotheses that participants using the adapted app will complete a higher percentage of weekly tasks (behavioral engagement: primary outcome) and score higher on self-awareness measures (experiential engagement).
RESULTS RESULTS
Recruitment commenced in April 2021. Data collection was completed in September 2021. The results of this study will be communicated via publication in 2022.
CONCLUSIONS CONCLUSIONS
This study aims to understand how best to promote engagement with RMTs in depression research. The findings will help determine the most effective techniques for implementation in both future rounds of the RADAR Major Depressive Disorder study and, in the long term, clinical practice.
TRIAL REGISTRATION BACKGROUND
ClinicalTrials.gov NCT04972474; http://clinicaltrials.gov/ct2/show/NCT04972474.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID) UNASSIGNED
DERR1-10.2196/32653.

Identifiants

pubmed: 34932005
pii: v10i12e32653
doi: 10.2196/32653
pmc: PMC8734922
doi:

Banques de données

ClinicalTrials.gov
['NCT04972474']

Types de publication

Journal Article

Langues

eng

Pagination

e32653

Informations de copyright

©Katie M White, Faith Matcham, Daniel Leightley, Ewan Carr, Pauline Conde, Erin Dawe-Lane, Yatharth Ranjan, Sara Simblett, Claire Henderson, Matthew Hotopf. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 21.12.2021.

Références

Br J Psychiatry. 2002 May;180:461-4
pubmed: 11983645
J Abnorm Psychol. 2012 Feb;121(1):51-60
pubmed: 21842963
PLoS One. 2021 Jan 6;16(1):e0244955
pubmed: 33406120
Rheum Dis Clin North Am. 2019 May;45(2):159-172
pubmed: 30952390
J Affect Disord. 2020 Feb 15;263:413-419
pubmed: 31969272
Physiol Meas. 2020 Nov 10;41(10):10TR01
pubmed: 32947271
J Marital Fam Ther. 2012 Jul;38(3):502-14
pubmed: 22804468
BMJ Innov. 2016 Jan;2(1):14-21
pubmed: 27019745
Transl Behav Med. 2017 Jun;7(2):254-267
pubmed: 27966189
Bipolar Disord. 2020 Mar;22(2):182-190
pubmed: 31610074
JMIR Mhealth Uhealth. 2021 Jul 30;9(7):e29840
pubmed: 34328441
J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
Arch Intern Med. 2006 May 22;166(10):1092-7
pubmed: 16717171
JMIR Mhealth Uhealth. 2019 Jan 30;7(1):e11325
pubmed: 30698535
Prev Med Rep. 2018 Jul 29;11:267-273
pubmed: 30109172
Psychol Med. 1996 May;26(3):477-86
pubmed: 8733206
Syst Rev. 2016 Mar 24;5:48
pubmed: 27012940
BMC Med. 2017 Dec 12;15(1):215
pubmed: 29228943
BMC Psychiatry. 2019 Feb 18;19(1):72
pubmed: 30777041
Chron Respir Dis. 2017 Nov;14(4):407-419
pubmed: 27512084
J Health Serv Res Policy. 2011 Jul;16(3):172-6
pubmed: 21543380
Annu Rev Clin Psychol. 2017 May 8;13:23-47
pubmed: 28375728
JMIR Mhealth Uhealth. 2018 Nov 29;6(11):e10123
pubmed: 30497999
Psychol Med. 2004 Aug;34(6):1001-11
pubmed: 15554571
J Psychosom Res. 2006 Jun;60(6):631-7
pubmed: 16731240
J Ment Health. 2015;24(5):321-32
pubmed: 26017625
Psychol Med. 2017 Jan;47(2):279-289
pubmed: 27702414
Front Psychiatry. 2021 Jan 28;12:625247
pubmed: 33584388
Pharmacoeconomics. 2021 Jun;39(6):653-665
pubmed: 33950419
Lancet Psychiatry. 2020 Jul;7(7):e34
pubmed: 32563310
BMC Med Res Methodol. 2018 Nov 26;18(1):151
pubmed: 30477443
JAMA. 2001 Apr 18;285(15):2006-7
pubmed: 11308440
JMIR Mhealth Uhealth. 2019 Aug 01;7(8):e11734
pubmed: 31373275
J Med Internet Res. 2016 Dec 20;18(12):e330
pubmed: 27998876
J Med Internet Res. 2018 Jul 12;20(7):e10480
pubmed: 30001997
J Drug Assess. 2019 May 24;8(1):97-103
pubmed: 31192030
Am Soc Clin Oncol Educ Book. 2019 Jan;39:115-121
pubmed: 31099626
JMIR Mhealth Uhealth. 2019 Apr 11;7(4):e11500
pubmed: 30973342
Psychol Med. 1985 Feb;15(1):189-94
pubmed: 3991833
J Med Internet Res. 2020 May 29;22(5):e17572
pubmed: 32348255
JMIR Mhealth Uhealth. 2020 May 7;8(5):e16043
pubmed: 32379055
J Affect Disord. 2009 Apr;114(1-3):163-73
pubmed: 18752852
JMIR Mhealth Uhealth. 2020 Jan 3;8(1):e13244
pubmed: 31899454
Front Psychiatry. 2020 Sep 18;11:579934
pubmed: 33061927

Auteurs

Katie M White (KM)

Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Faith Matcham (F)

Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Daniel Leightley (D)

Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Ewan Carr (E)

Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Pauline Conde (P)

Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Erin Dawe-Lane (E)

Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Yatharth Ranjan (Y)

Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Sara Simblett (S)

Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Claire Henderson (C)

Health Service & Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
South London and Maudsley National Health Service Foundation Trust, London, United Kingdom.

Matthew Hotopf (M)

Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Classifications MeSH