Diagnostic assessment program for prostate cancer: Lessons learned after 2 years and degree of compliance to Canadian guidelines.


Journal

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
ISSN: 2282-4197
Titre abrégé: Arch Ital Urol Androl
Pays: Italy
ID NLM: 9308247

Informations de publication

Date de publication:
20 Dec 2021
Historique:
received: 21 09 2021
accepted: 17 10 2021
entrez: 22 12 2021
pubmed: 23 12 2021
medline: 24 12 2021
Statut: epublish

Résumé

In 2018, our Institute launched the Diagnostic Assessment Program (DAP) for prostate cancer. It enabled quick access to a urologist for patients presented to family physician with elevated PSA and allowed fast multidisciplinary patient care. We aim to document our data over 2 years in comparison to data before implementation of DAP and its impact on the degree of adherence to Canadian guidelines. From April 2016 to April 2020, 880 patients who were evaluated for prostate cancer at Thunder Bay Regional Health Sciences Centre (TBRHSC) were included in this study. Patients' characteristics, clinical data, waiting times and line of treatment before and after implementation of DAP were calculated and statistically analysed. The median waiting time to urology consultation was significantly reduced from 68 (IQR 27-168) days to 34 (23-44) days (p < 0.001). The time from patient's referral to prostate biopsy decreased substantially from 34 (20-66) days to 18(11- 25) days after DAP (p < 0.001). After DAP, the percentage of Gleason 6 detected prostate cancers were significantly increased (19.7% to 30%) (p = 0.02). After DAP, rate for intermediate-risk patients elected for external beam radiotherapy (from 53.5% to 57.9%, p = 0.53) and radical prostatectomy (from 34.5% to 39.4%, p = 0.47) increased. More compliance to Canadian guidelines was observed in intermediate risk patients (88% vs 97.3%, p =.008). Implementation of DAP has led to a notable reduction of waiting time to urology consult and prostate biopsy. There is significant increase in Gleason 6 detected prostate cancer. Increased compliance to Canadian guidelines was detected in intermediate risk patients.

Sections du résumé

BACKGROUND BACKGROUND
In 2018, our Institute launched the Diagnostic Assessment Program (DAP) for prostate cancer. It enabled quick access to a urologist for patients presented to family physician with elevated PSA and allowed fast multidisciplinary patient care. We aim to document our data over 2 years in comparison to data before implementation of DAP and its impact on the degree of adherence to Canadian guidelines.
METHODS METHODS
From April 2016 to April 2020, 880 patients who were evaluated for prostate cancer at Thunder Bay Regional Health Sciences Centre (TBRHSC) were included in this study. Patients' characteristics, clinical data, waiting times and line of treatment before and after implementation of DAP were calculated and statistically analysed.
RESULTS RESULTS
The median waiting time to urology consultation was significantly reduced from 68 (IQR 27-168) days to 34 (23-44) days (p < 0.001). The time from patient's referral to prostate biopsy decreased substantially from 34 (20-66) days to 18(11- 25) days after DAP (p < 0.001). After DAP, the percentage of Gleason 6 detected prostate cancers were significantly increased (19.7% to 30%) (p = 0.02). After DAP, rate for intermediate-risk patients elected for external beam radiotherapy (from 53.5% to 57.9%, p = 0.53) and radical prostatectomy (from 34.5% to 39.4%, p = 0.47) increased. More compliance to Canadian guidelines was observed in intermediate risk patients (88% vs 97.3%, p =.008).
CONCLUSIONS CONCLUSIONS
Implementation of DAP has led to a notable reduction of waiting time to urology consult and prostate biopsy. There is significant increase in Gleason 6 detected prostate cancer. Increased compliance to Canadian guidelines was detected in intermediate risk patients.

Identifiants

pubmed: 34933523
doi: 10.4081/aiua.2021.4.389
doi:

Substances chimiques

Prostate-Specific Antigen EC 3.4.21.77

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

389-392

Auteurs

Waleed Shabana (W)

Northern Ontario School of Medicine, Thunder Bay, Ontario. waleed.shabana@gmail.com.

Ahmed Kotb (A)

Northern Ontario School of Medicine, Thunder Bay, Ontario. kotba@tbh.net.

Daniel Tesolin (D)

Northern Ontario School of Medicine, Thunder Bay, Ontario. dtesoln@nosm.ca.

Mohammed F K Ibrahim (MFK)

Northern Ontario School of Medicine, Thunder Bay, Ontario. ibrahimm@tbh.net.

Kristi Dolcetti (K)

Northern Ontario School of Medicine, Thunder Bay, Ontario. dolcetk@tbh.net.

Amy Boucher (A)

Northern Ontario School of Medicine, Thunder Bay, Ontario. bouchra@tbh.net.

Mohammed Bassuony (M)

Northern Ontario School of Medicine, Thunder Bay, Ontario. Bassunm@tbh.net.

Kevin Ramchandar (K)

Northern Ontario School of Medicine, Thunder Bay, Ontario. ramchnk@tbh.net.

Ahmed S Zakaria (AS)

Northern Ontario School of Medicine, Thunder Bay, Ontario. aszakari81@yahoo.com.

Hazem Elmansy (H)

Northern Ontario School of Medicine, Thunder Bay, Ontario. elmancyh@tbh.net.

Walid Shahrour (W)

Northern Ontario School of Medicine, Thunder Bay, Ontario. walid.shahrou@gmail.com.

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Classifications MeSH