Lichen planus flare following COVID-19 vaccination: A case report.
COVID‐19 cutaneous
COVID‐19 vaccination
COVID‐19 vaccine
COVID‐19 skin
lichen planus
Journal
Clinical case reports
ISSN: 2050-0904
Titre abrégé: Clin Case Rep
Pays: England
ID NLM: 101620385
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
23
08
2021
accepted:
03
11
2021
entrez:
22
12
2021
pubmed:
23
12
2021
medline:
23
12
2021
Statut:
epublish
Résumé
We report the third case of cutaneous lichen planus (LP) following COVID-19 BNT162b2 vaccination in a 59-year-old woman with previous LP. The reactivation of LP in patients with dormant LP suggests a possible vaccine-induced immune dysregulation. We suggest that the already described vaccine-induced upregulation of Th1 response may play a relevant role in LP reactivation, through an increase in inflammatory cytokines involved in the pathogenesis of LP. Interestingly, LP has already been associated with vaccinations and viral infections including COVID-19 disease. However, the exact mechanism underlying LP (re)activation after Pfizer-BiotNtech COVID-19 vaccination is still widely unknown and needs to be further investigated.
Identifiants
pubmed: 34934493
doi: 10.1002/ccr3.5092
pii: CCR35092
pmc: PMC8650756
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e05092Informations de copyright
© 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to declare.
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