Severe Acute Motor Axonal Neuropathy associated with Influenza-A (H1N1) Infection and Prolonged Respiratory Failure - A Case Report.

Guillain-Barre syndrome acute motor axonal neuropathy influenza virus A H1N1 nodopathy prolonged respiratory failure tetraplegia

Journal

Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)
ISSN: 2393-1809
Titre abrégé: J Crit Care Med (Targu Mures)
Pays: Poland
ID NLM: 101706934

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 26 02 2021
accepted: 29 07 2021
entrez: 22 12 2021
pubmed: 23 12 2021
medline: 23 12 2021
Statut: epublish

Résumé

Acute Motor Axonal Neuropathy (AMAN) is an immune-mediated disorder of the peripheral nervous system, part of the spectrum of the Guillain-Barre syndrome (GBS). An infectious event most often triggers it reported a few weeks before the onset. The reported case is of a 56 years-old woman who developed acute motor axonal neuropathy three weeks after respiratory infection with influenza A virus subtype H1N1. Despite early treatment with plasmapheresis and intravenous immunoglobulins, the patient remained tetraplegic, mechanically ventilated for five months, with repetitive unsuccessful weaning trails. The probable cause was considered to be phrenic nerve palsy in the context of acute motor axonal neuropathy. This case highlights that acute motor axonal neuropathy is a severe and life-threatening form of Guillain-Barre syndrome associated with significant mortality and morbidity. Neurological and physical recovery strongly depend on the inter-professional effort in an intensive care unit and neurology professionals.

Identifiants

pubmed: 34934821
doi: 10.2478/jccm-2021-0030
pii: jccm-2021-0030
pmc: PMC8647670
doi:

Types de publication

Journal Article

Langues

eng

Pagination

302-307

Informations de copyright

© 2021 Oana Mosora, Laura Barcutean, Rodica Balasa, Raluca Fodor, Smaranda Maier, Zoltan Bajko, Adina Stoian, Anca Motataianu, published by Sciendo.

Déclaration de conflit d'intérêts

Conflict of interest None to declare.

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Auteurs

Oana Mosora (O)

Neurology 1 Clinic, Emergency County Hospital Targu-Mures, Targu-Mures Romania.

Laura Barcutean (L)

Neurology 1 Clinic, Emergency County Hospital Targu-Mures, Targu-Mures Romania.
Neurology Department, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, Romania.

Rodica Balasa (R)

Neurology 1 Clinic, Emergency County Hospital Targu-Mures, Targu-Mures Romania.
Neurology Department, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, Romania.

Raluca Fodor (R)

Anaesthesiology Department, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, Romania.

Smaranda Maier (S)

Neurology 1 Clinic, Emergency County Hospital Targu-Mures, Targu-Mures Romania.
Neurology Department, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, Romania.

Zoltan Bajko (Z)

Neurology 1 Clinic, Emergency County Hospital Targu-Mures, Targu-Mures Romania.
Neurology Department, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, Romania.

Adina Stoian (A)

Neurology 1 Clinic, Emergency County Hospital Targu-Mures, Targu-Mures Romania.
Pathophysiology Department, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, Romania.

Anca Motataianu (A)

Neurology 1 Clinic, Emergency County Hospital Targu-Mures, Targu-Mures Romania.
Neurology Department, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, Romania.

Classifications MeSH