A comprehensive epidemiological study of rosacea in Germany.


Journal

European journal of dermatology : EJD
ISSN: 1952-4013
Titre abrégé: Eur J Dermatol
Pays: France
ID NLM: 9206420

Informations de publication

Date de publication:
01 Dec 2021
Historique:
pubmed: 23 12 2021
medline: 22 2 2022
entrez: 22 12 2021
Statut: ppublish

Résumé

Rosacea is one of the most common skin diseases causing great distress in affected patients. For optimal patient care, epidemiological studies on disease distribution and clinical aspects are essential. The goal of this study was to provide an updated perspective on the current state of rosacea epidemiology in Germany. A cohort of 777 rosacea patients was assessed based on a detailed online questionnaire. Information regarding patients' demographics, course and clinical presentation of rosacea, trigger factors, dermatological consultations, treatment adherence and satisfaction as well as quality of life were obtained. There was a very high self-reported prevalence of primary and secondary rosacea features (flushing: n = 726, 93.4%; papules/pustules: n = 613, 79.0%; telangiectasia: n = 590, 75.9%; sub jective symptoms: n = 691, 88.9%). However, these clinical findings were often underdiagnosed by the treating physicians, while changes in temperature and ultraviolet radiation were potent triggers across all patients (86.3%, 77.7%, respectively). Disease-related quality of life decreased with the number of drugs prescribed as well as with uncontrolled symptom activity, and was reduced in female patients. This study is the largest German-based assessment exclusively focusing on rosacea patients covering a variety of clinical aspects to optimize patient care.

Sections du résumé

BACKGROUND BACKGROUND
Rosacea is one of the most common skin diseases causing great distress in affected patients. For optimal patient care, epidemiological studies on disease distribution and clinical aspects are essential.
OBJECTIVES OBJECTIVE
The goal of this study was to provide an updated perspective on the current state of rosacea epidemiology in Germany.
MATERIALS & METHODS METHODS
A cohort of 777 rosacea patients was assessed based on a detailed online questionnaire. Information regarding patients' demographics, course and clinical presentation of rosacea, trigger factors, dermatological consultations, treatment adherence and satisfaction as well as quality of life were obtained.
RESULTS RESULTS
There was a very high self-reported prevalence of primary and secondary rosacea features (flushing: n = 726, 93.4%; papules/pustules: n = 613, 79.0%; telangiectasia: n = 590, 75.9%; sub jective symptoms: n = 691, 88.9%). However, these clinical findings were often underdiagnosed by the treating physicians, while changes in temperature and ultraviolet radiation were potent triggers across all patients (86.3%, 77.7%, respectively). Disease-related quality of life decreased with the number of drugs prescribed as well as with uncontrolled symptom activity, and was reduced in female patients.
CONCLUSION CONCLUSIONS
This study is the largest German-based assessment exclusively focusing on rosacea patients covering a variety of clinical aspects to optimize patient care.

Identifiants

pubmed: 34935620
pii: ejd.2021.4165
doi: 10.1684/ejd.2021.4165
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

744-751

Auteurs

Stephan Zierl (S)

Department of Dermatology and Allergy, University Hospital of Munich, LMU, Germany.

Anne Guertler (A)

Department of Dermatology and Allergy, University Hospital of Munich, LMU, Germany.

Johannes A Hildebrand (JA)

Department of Dermatology and Allergy, University Hospital of Munich, LMU, Germany.

Benjamin M Clanner-Engelshofen (BM)

Department of Dermatology and Allergy, University Hospital of Munich, LMU, Germany.

Lars E French (LE)

Department of Dermatology and Allergy, University Hospital of Munich, LMU, Germany, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, USA.

Markus Reinholz (M)

Department of Dermatology and Allergy, University Hospital of Munich, LMU, Germany.

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Classifications MeSH