Pulmonary Artery Pseudoaneurysm in COVID-19-Associated Pulmonary Mucormycosis: Case Series and Systematic Review of the Literature.


Journal

Mycopathologia
ISSN: 1573-0832
Titre abrégé: Mycopathologia
Pays: Netherlands
ID NLM: 7505689

Informations de publication

Date de publication:
Feb 2022
Historique:
received: 11 10 2021
accepted: 06 12 2021
pubmed: 23 12 2021
medline: 4 2 2022
entrez: 22 12 2021
Statut: ppublish

Résumé

Literature on COVID-19-associated pulmonary mucormycosis (CAPM) is sparse. Pulmonary artery pseudoaneurysm (PAP) is an uncommon complication of pulmonary mucormycosis (PM), and rarely reported in CAPM. Herein, we report five cases of CAPM with PAP managed at our center and perform a systematic review of the literature. We diagnosed PM in those with clinico-radiological suspicion and confirmed it by microbiology or histopathology. We encountered five cases of CAPM with PAP (size ranged from 1 × 0.8 cm to ~ 4.9 × 4.8 cm). All subjects had diabetes and were aged 55-62 years (75% men). In two cases, COVID-19 and mucormycosis were diagnosed simultaneously, while in three others, COVID-19 preceded PM. One subject who underwent surgery survived, while all others died (80% mortality). From our systematic review, we identified one additional case of CAPM with PAP in a transplant recipient. CAPM with PAP is rare with high mortality. Early diagnosis and multimodality management are imperative to improve outcomes.

Identifiants

pubmed: 34936060
doi: 10.1007/s11046-021-00610-9
pii: 10.1007/s11046-021-00610-9
pmc: PMC8692820
doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

31-37

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer Nature B.V.

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Auteurs

Himanshu Pruthi (H)

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012, India.

Valliappan Muthu (V)

Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Harish Bhujade (H)

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012, India.

Arun Sharma (A)

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012, India.

Abhiman Baloji (A)

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012, India.

Rao G Ratnakara (RG)

Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Amanjit Bal (A)

Department of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Harkant Singh (H)

Department of Cardiothoracic Vascular Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Manavjit Singh Sandhu (MS)

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012, India.

Sunder Negi (S)

Department of Cardiac Anesthesia, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Arunaloke Chakrabarti (A)

Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Manphool Singhal (M)

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012, India. drmsinghal@yahoo.com.

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